Three-dimensional quantitative structure activity relationships (3-D-QSAR) of antihyperglycemic agents

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 7, 1999, Pages 1475-1485

  Kulkarni, Santosh S ^a   Gediya, Lalji K ^a   Kulkarni, Vithal M ^a  

^a INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

3 D QSAR; CoMFA; Receptor model; Thiazolidinedione antihyperglycemics

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT;

ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; ENERGY; MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS;

ANIMALS; COMPUTER SIMULATION; HYPOGLYCEMIC AGENTS; MICE; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032970182     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00063-2     Document Type: Article

References (30)

1. DeFronzo, R. A.; Bonadonna, R. C.; Ferrannini, E. Diabetes Care, 1992, 15, 318.
2. Reaven, G. M. Metabolism, 1980, 29, 445.
3. DeFronzo, R. A.; Ferrannini, E.; Koivisto, V. P. Am. J. Med., 1983, 74(Suppl. 1A), 52.
4. Olefsky, J. M.; Kolterman, O. G. Am. J. Med., 1981, 70, 151.
5. Reaven, G. Diabetes, 1988, 37, 1595.
6. Sohda, T.; Mizuno, K.; Imamiya, E.; Sugiyama, Y.; Fujita, T.; Kawamatsu, Y. Chem. Pharm. Bull., 1982, 30, 3580.
7. Fujita, T.; Sugiyama, Y.; Taketomi, S.; Sohda, T.; Kawamatsu, Y.; Iwatsuka, H.; Suzuoki, Z. Diabetes, 1983, 32, 804.
8. Lehmann, J. M.; Moore, L. B.; Smith-Oliver, T. A.; Wilkinson, W. O.; Willson, T. M.; Kliewer, S. A. J. Biol. Chem., 1995, 270, 12953.
9. Willson, T. M.; Cobb, J. E.; Cowan, D. J.; Wiethe, R. W.; Correa, I. D.; Prakash, S. R.; Beck, K. D.; Moore, L. B.; Kliewer, S. A.; Lehmann, J. M. J. Med. Chem., 1996, 39, 665.
10. Dow, R. L.; Bechle, B. M.; Chou, T. T.; Clark, D. A.; Hulin, B.; Stevenson, R. W. J. Med. Chem., 1991, 34, 1538.
11. Kees, K. L.; Cheeseman, R. S.; Prozialeck, D. H.; Steiner, K. E. J. Med. Chem., 1989, 32, 11.
12. Ellingboe, J. W.; Alessi, T. R.; Dolak, J. M.; Nguyen, T. T.; Tomer, J. D.; Guzzo, F.; Bagli, J. F.; McCaleb, M. L. J. Med. Chem., 1992, 35, 1176.
13. Hulin, B.; Newton, L. S.; Lewis, D. M.; Genereux, P. E.; Gibbs, E. M.; Clark, D. A. J. Med. Chem., 1996, 39, 3897.
14. Hulin, B.; Clark, D. A.; Goldstein, S. W.; McDermott, R. E.; Dambek, P. J.; Kappeler, W. H.; Lamphere, C. H.; Lewis, D. M.; Rizzi, J. D. J. Med. Chem., 1992, 35, 1853.
15. Zask, A.; Jirkvosky, I.; Nowicki, J. W.; McCaleb, M. L. J. Med. Chem., 1990, 33, 1418.
16. Arakawa, K.; Inamasu, M.; Matsumoto, M.; Okumura, K.; Yasuda, K.; Akatsuka, H.; Kawanami, S.; Watanabe, A.; Homma, K.; Saiga, Y.; Ozeki, M.; Iijima, I. Chem. Pharm. Bull. 1997, 45, 1984.
17. Sohda, T.; Mizuno, K.; Tawada, H.; Sugiyama, Y.; Fujita, T.; Kawamatsu, Y.; Chem. Pharm. Bull., 1982, 30, 3563.
18. Sohda, T.; Momose, Y.; Meguro, K.; Kawamatsu, Y.; Sugiyama, Y.; Ikeda, H. Arzeim-Forsch/Drug Des., 1990, 40, 37.
19. Sohda, T.; Mizuna, K.; Imamiya, E.; Sugiyama, Y.; Fujita, T.; Kawamatsu, T. Chem. Pharm. Bull., 1982, 30, 3580.
20. Cantello, B. C. C.; Cawthorne, M. A.; Cottam, G. P.; Duff, P. T.; Haigh, D.; Hindley, R. M.; Lister, C. A.; Smith, S. A.; Thurlby, P. L. J. Med. Chem., 1994, 37, 3977.
21. Sohda, T.; Mizuno, K.; Momose, Y.; Ikeda, H.; Fujita, T.; Meguro, K. J. Med. Chem., 1992, 35, 2617.
22. Cramer, R. D. III; Patterson, D. E.; Bunce, J. D. J. Am. Chem. Soc., 1988, 110, 5959.
23. Hariprasad, V.; Kulkarni, V. M. J. Comput. -Aided Mol. Design, 1996, 10, 284.
24. Kulkarni, S. S.; Kulkarni, V. M. J. Med. Chem. 1999, 42, 373.
25. Gokhale, V. M.; Kulkarni, V. M., J. Med. Chem. Communicated.
26. Nolte, R. T.; Wisely, G. B.; Westin, S.; Cobb, J. E.; Lambert, M. H.; Kurokawa, R.; Rosenfeld, M. G.; Willson, T. M.; Glass, C. K.; Milburn, M. V. Nature, 1998, 395, 137.
27. Tripos Associates, 1699, S. Hanley Road, Suite 303, St. Louis, Missouri, MO 63144-2913, USA.
28. Clark, M.; Cramer, R. D. III; Van Opdenbosh, N. J. Comput. Chem., 1989, 10, 982.
29. Wold, S.; Ruhe, A.; Wold, H.; Dunn W. J. III; SIAM J. Sci. Stat. Comput., 1984, 5, 735.
30. Cramer, R. D. III; Bunce, J. D.; Patterson, D. E. Quant. Struct. Act. Relat., 1988, 7, 18.