Pfiesteria toxin and learning performance

Neurotoxicology and Teratology

Volumn 21, Issue 3, 1999, Pages 215-221

  Levin, E D ^a   Simon, B B ^a   Schmechel, D E ^a,b   Glasgow Jr , H B ^b   Deamer Melia, N J ^b   Burkholder, J M ^b   Moser, V C ^c   Jensen, K ^c   Harry, G J ^d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Activity; Figure 8 maze; Learning; Pfiesteria piscicida; Radial arm maze

Indexed keywords

MARINE TOXIN;

ACCURACY; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DINOFLAGELLATE; FEMALE; INTOXICATION; LEARNING DISORDER; LOCOMOTION; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; SOUND; TRAINING;

ANIMALS; FEMALE; HUMANS; MAZE LEARNING; MOTOR ACTIVITY; PFIESTERIA PISCICIDA; PROTOZOAN INFECTIONS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

ANIMALIA; DINOPHYCEAE; PFIESTERIA; PFIESTERIA PISCICIDA;

EID: 0032966117     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0892-0362(98)00041-5     Document Type: Article

References (13)

1. Burkholder J.M., Glasgow H.B. Jr. Interactions of a toxic estuarine dinoflagellate with microbial predators and prey. Archiv. Protistenk. 145:1995;177-188.
2. Burkholder J.M., Glasgow H.B. Jr. Pfiesteria piscicida and Pfiesteria-like dinoflagellates. Behavioral impacts and environmental controls Limnol. Oceanogr. 42:1997;1052-1075.
3. Burkholder J.M., Glasgow H.B. Jr., Noga E.J., Hobbs C.W. The role of a new toxic dinoflagellate in finfish and shellfish kills in the Neuse and Pamlico Estuaries. Ablemarle-Pamlico estuarine study. 1993;1-58 North Carolina Department of Environmental health and Natural Resourses and EPA National Estuarine Program, Raleigh, NC.
4. Burkholder J.M., Noga E.J., Hobbs C.W., Glasgow H.B. Jr., Smith S.A. New "phantom" dinoflagellate is the cusative agent of major estuarine fish kills. Nature. 358:1992;407-410.
5. Creason J. Data evaluation and statistical analysis of functional observational battery data using a linear models approach. J. Am. Coll. Toxicol. 8:1989;157-170.
6. Crofton K.M., Howard J.L., Moser V.C., Gill M.W., Reiter L.W., Tilson H.A., MacPhail R.C. Interlaboratory comparisons of motor activity experiments. Implications for neurotoxicological assessments Neurotoxicol. Teratol. 13:1991;599-609.
7. Glasgow H.B. Jr., Burkholder J.M., Schmechel D.E., Tester P.A., Rublee P.A. Insidious effects of a toxic estuarine dinoflagellate on fish survival and human health. J. Toxicol. Environ. Health. 46:1995;501-522.
8. Grattan L., Oldach D., Perl T., Lowitt M., Matuszak D., Dickson C., Parrott C., Shoemaker R., Kauffman C., Wasserman M., Hebel J., Charache P., Morris J.J. Learning and memory difficulties after environmental exposure to waterways containing toxin-producing Pfiesteria or Pfiesteria-like dinoflagellates. Lancet. 352:1998;532-539.
9. Levin E.D., Schmechel D.E., Burkholder J.M., Glasgow H.B. Jr., Deamer-Melia N., Moser V.C., Harry J.G. Persisting learning deficits in rats after exposure to Pfiesteria piscicida. Environ. Health Perspect. 105:1997;1320-1325.
10. McCellan-Green P.D., Noga E., Baden D., Jaykus L.A., Green D.P. Cytotoxicity of a putative toxin from the Pfiesteria piscicida dinoflagellate. Toxicologist. 36:1997;276.
11. McDaniel K.L., Moser V.C. Utility of a neurobehavioral screening battery for differentiating the effects of two pyrethroids, permethrin and cypermethrin. Neurotoxicol. Teratol. 15:1993;71-83.
12. Moser V.C., McCormick J.P., Creason J.P., MacPhail R.C. Comparison of chlordimeform and carbaryl using a functional observational battery. Fundam. Appl. Toxicol. 11:1988;189-206.
13. SAS Institute: SAS/STAT user's guide, version 6. Cary, NC: SAS Institute Inc.; 1990.