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Volumn 7, Issue 2, 1996, Pages 121-128

Tumour heterogeneity and clonality - An old theme revisited

Author keywords

Clonal evolution; Clonality; Molecular tumour markers; Tumour heterogeneity

Indexed keywords

TUMOR MARKER;

EID: 0029963179     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.annonc.a010537     Document Type: Review
Times cited : (24)

References (88)
  • 1
    • 0022600767 scopus 로고
    • Mechanisms of tumor progression
    • Nowell P.C. Mechanisms of tumor progression Cancer Res 46 1986 2203 2207
    • (1986) Cancer Res , vol.46 , pp. 2203-2207
    • Nowell, P.C.1
  • 2
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbitts T.H. Chromosomal translocations in human cancer Nature 372 1994 143 149
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbitts, T.H.1
  • 3
    • 0025343444 scopus 로고
    • Assessment of clonality in human tumours: A review
    • Wainscoat J.S. Fey M.F. Assessment of clonality in human tumours: A review Cancer Res 50 1990 1355 1360
    • (1990) Cancer Res , vol.50 , pp. 1355-1360
    • Wainscoat, J.S.1    Fey, M.F.2
  • 4
    • 0019941487 scopus 로고
    • Biological diversity in metastatic neoplasms: Origins and implications
    • Fidler I.J. Hart I.R. Biological diversity in metastatic neoplasms: Origins and implications Science 217 1982 998 1003
    • (1982) Science , vol.217 , pp. 998-1003
    • Fidler, I.J.1    Hart, I.R.2
  • 5
    • 0019983407 scopus 로고
    • Evidence for the clonal origin of spontaneous metastases
    • Talmadge J.E. Wolman S.R. Fidler I.J. Evidence for the clonal origin of spontaneous metastases Science 217 1982 361 363
    • (1982) Science , vol.217 , pp. 361-363
    • Talmadge, J.E.1    Wolman, S.R.2    Fidler, I.J.3
  • 6
    • 0025301851 scopus 로고
    • The cellular basis of site-specific tumor metastases
    • Zetter B.R. The cellular basis of site-specific tumor metastases N Engl J Med 322 1990 605 612
    • (1990) N Engl J Med , vol.322 , pp. 605-612
    • Zetter, B.R.1
  • 7
    • 0017704436 scopus 로고
    • Metastasis results from preexisting variant cells within a malignant tumor
    • Fidler I.J. Kripke M.L. Metastasis results from preexisting variant cells within a malignant tumor Science 197 1977 893 895
    • (1977) Science , vol.197 , pp. 893-895
    • Fidler, I.J.1    Kripke, M.L.2
  • 8
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the p210bcr/abl gene of the Philadelphia chromosome
    • bcr/abl gene of the Philadelphia chromosome Science 247 1990 824 830
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    van Etten, R.A.2    Baltimore, D.3
  • 9
    • 0026556689 scopus 로고
    • Clonal development and karyotype evolution during leukemogenesis of BCR/ABL transgenic mice
    • Voncken J.W. Morris C. Pattengale P. Clonal development and karyotype evolution during leukemogenesis of BCR/ABL transgenic mice Blood 79 1992 1029 1036
    • (1992) Blood , vol.79 , pp. 1029-1036
    • Voncken, J.W.1    Morris, C.2    Pattengale, P.3
  • 10
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B. Fearon E.R. Hamilton S.R. Genetic alterations during colorectal-tumor development N Engl J Med 319 1988 525 532
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 11
    • 0026457950 scopus 로고
    • Multistep carcinogenesis: A 1992 perspective
    • Sugimura T. Multistep carcinogenesis: A 1992 perspective Science 258 1992 603 607
    • (1992) Science , vol.258 , pp. 603-607
    • Sugimura, T.1
  • 12
    • 0027354561 scopus 로고
    • Genomic instability and tumor progression: Mechanistic considerations
    • Cheng K.C. Loeb L.A. Genomic instability and tumor progression: Mechanistic considerations Adv Cancer Res 60 1993 121 155
    • (1993) Adv Cancer Res , vol.60 , pp. 121-155
    • Cheng, K.C.1    Loeb, L.A.2
  • 14
    • 0023705310 scopus 로고
    • Tumor clonality and its biological significance
    • Woodruff M.F.A. Tumor clonality and its biological significance Adv Cancer Res 50 1988 197 229
    • (1988) Adv Cancer Res , vol.50 , pp. 197-229
    • Woodruff, M.F.A.1
  • 15
    • 0024390277 scopus 로고
    • Clonal allele loss in gastrointestinal cancers
    • Fey M.F. Hesketh C. Wainscoat J.S. Clonal allele loss in gastrointestinal cancers Br J Cancer 59 1989 750 754
    • (1989) Br J Cancer , vol.59 , pp. 750-754
    • Fey, M.F.1    Hesketh, C.2    Wainscoat, J.S.3
  • 17
    • 0027183353 scopus 로고
    • Role of chromosome 9 in human bladder cancer
    • Miyao N. Tsai Y.C. Lerner S.P. Role of chromosome 9 in human bladder cancer Cancer Res 53 1993 4066 4070
    • (1993) Cancer Res , vol.53 , pp. 4066-4070
    • Miyao, N.1    Tsai, Y.C.2    Lerner, S.P.3
  • 18
    • 0026786662 scopus 로고
    • Unifocal origin of advanced human epithelial ovarian cancers
    • Mok C.-H. Tsao S.W. Knapp R.C. Unifocal origin of advanced human epithelial ovarian cancers Cancer Res 52 1992 5119 5122
    • (1992) Cancer Res , vol.52 , pp. 5119-5122
    • Mok, C.-H.1    Tsao, S.W.2    Knapp, R.C.3
  • 19
    • 0027476142 scopus 로고
    • Molecular genetic evidence of a unifocal origin for human serous ovarian carcinomas
    • Tsao S. Mok S.C.H. Knapp R.C. Molecular genetic evidence of a unifocal origin for human serous ovarian carcinomas Gynecol Oncol 48 1993 5 10
    • (1993) Gynecol Oncol , vol.48 , pp. 5-10
    • Tsao, S.1    Mok, S.C.H.2    Knapp, R.C.3
  • 20
    • 0024204608 scopus 로고
    • Assessment of clonality in gastrointestinal cancer by DNA fingerprinting
    • Fey M.F. Wells R.A. Wainscoat J.S. Assessment of clonality in gastrointestinal cancer by DNA fingerprinting J Clin Invest 82 1988 1532 1537
    • (1988) J Clin Invest , vol.82 , pp. 1532-1537
    • Fey, M.F.1    Wells, R.A.2    Wainscoat, J.S.3
  • 21
    • 0025282062 scopus 로고
    • Demonstration of somatic rearrangements and genomic heterogeneity in human ovarian cancer by DNA fingerprinting
    • Boltz E.M. Hamett P. Leary J. Demonstration of somatic rearrangements and genomic heterogeneity in human ovarian cancer by DNA fingerprinting Br J Cancer 62 1990 23 27
    • (1990) Br J Cancer , vol.62 , pp. 23-27
    • Boltz, E.M.1    Hamett, P.2    Leary, J.3
  • 22
    • 0028954509 scopus 로고
    • Evidence for a multifocal origin of papillary serous carcinoma of the peritoneum
    • Muto M.G. Welch W.R. Mok S.C.H. Evidence for a multifocal origin of papillary serous carcinoma of the peritoneum Cancer Res 55 1995 490 492
    • (1995) Cancer Res , vol.55 , pp. 490-492
    • Muto, M.G.1    Welch, W.R.2    Mok, S.C.H.3
  • 23
    • 0026632451 scopus 로고
    • Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma
    • Oda T. Tsuda H. Scarpa A. Mutation pattern of the p53 gene as a diagnostic marker for multiple hepatocellular carcinoma Cancer Res 52 1992 3674 3678
    • (1992) Cancer Res , vol.52 , pp. 3674-3678
    • Oda, T.1    Tsuda, H.2    Scarpa, A.3
  • 24
    • 0027358775 scopus 로고
    • Multiple hepatocellular carcinomas at the early stage have different clonality
    • Sheu J.C. Huang G.T. Chou H.C. Multiple hepatocellular carcinomas at the early stage have different clonality Gastro-enterology 105 1993 1471 1476
    • (1993) Gastro-enterology , vol.105 , pp. 1471-1476
    • Sheu, J.C.1    Huang, G.T.2    Chou, H.C.3
  • 25
    • 0028792410 scopus 로고
    • Allelic loss and the progression of breast cancer
    • Radford D.M. Philips N.J. Fair K.L. Allelic loss and the progression of breast cancer Cancer Res 55 1995 5180 5183
    • (1995) Cancer Res , vol.55 , pp. 5180-5183
    • Radford, D.M.1    Philips, N.J.2    Fair, K.L.3
  • 26
    • 0029144461 scopus 로고
    • Identification of multiple breast cancers of multicentric origin by histological observations and distribution of allele loss on chromosome 16q
    • Tsuda H. Hirohashi S. Identification of multiple breast cancers of multicentric origin by histological observations and distribution of allele loss on chromosome 16q Cancer Res 55 1995 3395 3398
    • (1995) Cancer Res , vol.55 , pp. 3395-3398
    • Tsuda, H.1    Hirohashi, S.2
  • 27
    • 0028129767 scopus 로고
    • Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysis
    • Noguchi S. Aihara T. Koyama H. Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysis Cancer 74 1994 872 877
    • (1994) Cancer , vol.74 , pp. 872-877
    • Noguchi, S.1    Aihara, T.2    Koyama, H.3
  • 28
    • 0026708851 scopus 로고
    • Clonal analysis of human tumours with M27ß, a highly informative polymorphic X-chromosomal probe
    • Fey M.F. Peter H.J. Hinds H.L. Clonal analysis of human tumours with M27ß, a highly informative polymorphic X-chromosomal probe J Clin Invest 89 1992 1438 1444
    • (1992) J Clin Invest , vol.89 , pp. 1438-1444
    • Fey, M.F.1    Peter, H.J.2    Hinds, H.L.3
  • 29
    • 0028928694 scopus 로고
    • Identical allelic loss on chromosome 11q13 in micro-dissected in situ and invasive human breast cancer
    • Zhuang Z. Merino M.J. Chuaqui R. Identical allelic loss on chromosome 11q13 in micro-dissected in situ and invasive human breast cancer Cancer Res 55 1995 467 471
    • (1995) Cancer Res , vol.55 , pp. 467-471
    • Zhuang, Z.1    Merino, M.J.2    Chuaqui, R.3
  • 30
    • 0029038556 scopus 로고
    • Molecular genetic analysis demonstrates that multiple posttransplantation lymphoproliferative disorders occurring in one anatomic site in a single patient represent distinct primary lymphoid neoplasms
    • Chadburn A. Cesarman E. Liu Y.F. Molecular genetic analysis demonstrates that multiple posttransplantation lymphoproliferative disorders occurring in one anatomic site in a single patient represent distinct primary lymphoid neoplasms Cancer 75 1995 2747 2756
    • (1995) Cancer , vol.75 , pp. 2747-2756
    • Chadburn, A.1    Cesarman, E.2    Liu, Y.F.3
  • 31
    • 0021833639 scopus 로고
    • Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency
    • Shearer W.T. Ritz J. Finegold M.J. Epstein-Barr virus-associated B-cell proliferations of diverse clonal origins after bone marrow transplantation in a 12-year-old patient with severe combined immunodeficiency N Engl J Med 312 1985 1151 1159
    • (1985) N Engl J Med , vol.312 , pp. 1151-1159
    • Shearer, W.T.1    Ritz, J.2    Finegold, M.J.3
  • 32
    • 0028275952 scopus 로고
    • Clonal analysis of posttransplant lymphoproliferative disorders, using both episomal Epstein-Barr virus and immunoglobulin genes as markers
    • Kaplan M.A. Ferry J A. Harris N.L. Jacobson J.O. Clonal analysis of posttransplant lymphoproliferative disorders, using both episomal Epstein-Barr virus and immunoglobulin genes as markers Am J Clin Pathol 101 1994 590 596
    • (1994) Am J Clin Pathol , vol.101 , pp. 590-596
    • Kaplan, M.A.1    Ferry J, A.2    Harris, N.L.3    Jacobson, J.O.4
  • 33
    • 0021138830 scopus 로고
    • Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphomas
    • Cleary M.L. Sklar J. Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphomas Lancet 11 1984 489 493
    • (1984) Lancet , vol.11 , pp. 489-493
    • Cleary, M.L.1    Sklar, J.2
  • 34
    • 0023707382 scopus 로고
    • Clonal analysis of transplant-associated lymphoproliferations based on the structure on the genomic termini of the Epstein-Barr virus
    • Cleary M.L. Nalesnik M.A. Shearer W.T. Sklar J. Clonal analysis of transplant-associated lymphoproliferations based on the structure on the genomic termini of the Epstein-Barr virus Blood 72 1988 349 352
    • (1988) Blood , vol.72 , pp. 349-352
    • Cleary, M.L.1    Nalesnik, M.A.2    Shearer, W.T.3    Sklar, J.4
  • 35
    • 0026757057 scopus 로고
    • Epstein-Barr virus-associated anaplastic large cell lymphoma in renal transplant patients
    • Borisch B. Gatter K.C. Tobler A. Epstein-Barr virus-associated anaplastic large cell lymphoma in renal transplant patients Am J Clin Pathol 98 1992 312 318
    • (1992) Am J Clin Pathol , vol.98 , pp. 312-318
    • Borisch, B.1    Gatter, K.C.2    Tobler, A.3
  • 36
    • 0022895276 scopus 로고
    • The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation
    • Raab-Traub N. Flynn K. The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation Cell 47 1986 883 889
    • (1986) Cell , vol.47 , pp. 883-889
    • Raab-Traub, N.1    Flynn, K.2
  • 37
    • 0029134785 scopus 로고
    • Hodgkin's disease with monoclonal and polyclonal populations of Reed-Stern-berg cells
    • Hummel M. Ziemann K. Lammert H. Hodgkin's disease with monoclonal and polyclonal populations of Reed-Stern-berg cells N Engl J Med 333 1995 901 906
    • (1995) N Engl J Med , vol.333 , pp. 901-906
    • Hummel, M.1    Ziemann, K.2    Lammert, H.3
  • 38
    • 0028321495 scopus 로고
    • Allelic loss of chromosome 18q and prognosis in colorectal cancer
    • Jen J. Kim H. Piantadosi S. Allelic loss of chromosome 18q and prognosis in colorectal cancer N Engl J Med 331 1994 213 221
    • (1994) N Engl J Med , vol.331 , pp. 213-221
    • Jen, J.1    Kim, H.2    Piantadosi, S.3
  • 39
    • 0029031158 scopus 로고
    • Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intra-tumor heterogeneity in gastrointestinal cancers
    • Nagel S. Borisch B. Thein S.L. Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intra-tumor heterogeneity in gastrointestinal cancers Cancer Res 55 1995 2866 2870
    • (1995) Cancer Res , vol.55 , pp. 2866-2870
    • Nagel, S.1    Borisch, B.2    Thein, S.L.3
  • 40
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
    • Bronner C.E. Baker S.M. Morrison P.T. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer Nature 368 1994 258 261
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1    Baker, S.M.2    Morrison, P.T.3
  • 41
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R. Lescoe M.X. Rao M.R.S. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer Cell 75 1993 1027 1038
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.X.2    Rao, M.R.S.3
  • 42
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach F.S. Nicolaides N.C. Papdopoulos N. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer Cell 75 1993 1215 1225
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papdopoulos, N.3
  • 43
    • 0027933070 scopus 로고
    • Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
    • Nicoloides N.C. Papdopoulos N. Liu B. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer Nature 371 1994 75 80
    • (1994) Nature , vol.371 , pp. 75-80
    • Nicoloides, N.C.1    Papdopoulos, N.2    Liu, B.3
  • 44
    • 0028138341 scopus 로고
    • Microsatellite alterations as clonal markers for the detection of human cancer
    • Mao L. Lee D.J. Tockman M.S. Microsatellite alterations as clonal markers for the detection of human cancer Proc Natl Acad Sci 91 1994 9871 9875
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 9871-9875
    • Mao, L.1    Lee, D.J.2    Tockman, M.S.3
  • 46
    • 0027474820 scopus 로고
    • Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma
    • Ookawa K. Sakamoto M. Hirohashi S. Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma Int J Cancer 53 1993 382 387
    • (1993) Int J Cancer , vol.53 , pp. 382-387
    • Ookawa, K.1    Sakamoto, M.2    Hirohashi, S.3
  • 47
    • 0028243778 scopus 로고
    • Allelic loss in locally metastatic, multisampled prostate cancer
    • Sakr W.A. Macoska J.A. Benson P. Allelic loss in locally metastatic, multisampled prostate cancer Cancer Res 54 1994 3273 3277
    • (1994) Cancer Res , vol.54 , pp. 3273-3277
    • Sakr, W.A.1    Macoska, J.A.2    Benson, P.3
  • 48
    • 0029067371 scopus 로고
    • Allelic loss on chromosome 8pl2–21 in microdissected prostatic intra-epithelial neoplasia
    • Emmert-Buck M.R. Vocke C.D. Pozzatti R.O. Allelic loss on chromosome 8pl2–21 in microdissected prostatic intra-epithelial neoplasia Cancer Res 55 1995 2959 2962
    • (1995) Cancer Res , vol.55 , pp. 2959-2962
    • Emmert-Buck, M.R.1    Vocke, C.D.2    Pozzatti, R.O.3
  • 49
    • 0028997479 scopus 로고
    • Genomic instability of microsatellite repeats in prostate cancer Relationship to clini-copathological variables
    • Egawa S. Uchida T. Suyama K. Genomic instability of microsatellite repeats in prostate cancer Relationship to clini-copathological variables Cancer Res 55 1995 2418 2421
    • (1995) Cancer Res , vol.55 , pp. 2418-2421
    • Egawa, S.1    Uchida, T.2    Suyama, K.3
  • 50
    • 0025012831 scopus 로고
    • Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction
    • Sawyers C.L. Timson L. Kawasaki E. Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction Proc Natl Acad Sci USA 87 1990 563 567
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 563-567
    • Sawyers, C.L.1    Timson, L.2    Kawasaki, E.3
  • 51
    • 0024551067 scopus 로고
    • Polymerase chain reaction for detection of residual leukaemia
    • Morgan G.J. Hughes T. Janssen J.W.G. Polymerase chain reaction for detection of residual leukaemia Lancet I 1989 928 929
    • (1989) Lancet , vol.I , pp. 928-929
    • Morgan, G.J.1    Hughes, T.2    Janssen, J.W.G.3
  • 52
    • 0026446190 scopus 로고
    • Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia
    • Lo Coco F. Diverio D. pandolfi P.P. Molecular evaluation of residual disease as a predictor of relapse in acute promyelocytic leukaemia Lancet 340 1992 1437 1438
    • (1992) Lancet , vol.340 , pp. 1437-1438
    • Lo Coco, F.1    Diverio, D.2    pandolfi, P.P.3
  • 53
    • 0027133214 scopus 로고
    • Absence of reverse transcription-polymerase chain reaction detectable residual disease in patients with acute promyelocytic leukemia in long term remission
    • Diverio D. Pandolfi P.P. Biondi A. Absence of reverse transcription-polymerase chain reaction detectable residual disease in patients with acute promyelocytic leukemia in long term remission Blood 82 1993 3556 3559
    • (1993) Blood , vol.82 , pp. 3556-3559
    • Diverio, D.1    Pandolfi, P.P.2    Biondi, A.3
  • 55
    • 0027194394 scopus 로고
    • Acute promyelocytic leukemia: Clinical relevance of two major PML-RARα isoforms and detection of minimal residual disease by retrotranscriptase/ polymerase chain reaction to predict relapse
    • Huang W. Sun Gl Li X.S. Acute promyelocytic leukemia: Clinical relevance of two major PML-RARα isoforms and detection of minimal residual disease by retrotranscriptase/ polymerase chain reaction to predict relapse Blood 82 1993 1264 1269
    • (1993) Blood , vol.82 , pp. 1264-1269
    • Huang, W.1    Sun, Gl2    Li, X.S.3
  • 56
    • 0026071619 scopus 로고
    • Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients
    • Yokota S. Hansen-Hagge T.E. Ludwig W.D. Use of polymerase chain reactions to monitor minimal residual disease in acute lymphoblastic leukemia patients Blood 77 1991 331 339
    • (1991) Blood , vol.77 , pp. 331-339
    • Yokota, S.1    Hansen-Hagge, T.E.2    Ludwig, W.D.3
  • 57
    • 0025365924 scopus 로고
    • Minimal residual disease in childhood B-lineage lymphoblastic leukemia. Persistence of leukemic cells during the first 18 months of treatment
    • Yamada M. Wasserman R. Lange B. Minimal residual disease in childhood B-lineage lymphoblastic leukemia. Persistence of leukemic cells during the first 18 months of treatment N Engl J Med 323 1990 448 455
    • (1990) N Engl J Med , vol.323 , pp. 448-455
    • Yamada, M.1    Wasserman, R.2    Lange, B.3
  • 58
    • 0026011458 scopus 로고
    • Detection of minimal residual disease in childhood leukemia with the polymerase chain reaction
    • Beishuizen A. Hählen K. van Wering E.R. van Dongen J.J.M. Detection of minimal residual disease in childhood leukemia with the polymerase chain reaction N Engl J Med 324 1991 772 775
    • (1991) N Engl J Med , vol.324 , pp. 772-775
    • Beishuizen, A.1    Hählen, K.2    van Wering, E.R.3    van Dongen, J.J.M.4
  • 59
    • 0026327554 scopus 로고
    • Extensive junctional diversity of γδ T-cell receptors expressed by T-cell acute lymphoblastic leukemias: Implication for the detection of minimal residual disease
    • Breit T. Wolvers-Tettero I.L.M. Hählen K. Extensive junctional diversity of γδ T-cell receptors expressed by T-cell acute lymphoblastic leukemias: Implication for the detection of minimal residual disease Leukemia 5 1991 1076 1086
    • (1991) Leukemia , vol.5 , pp. 1076-1086
    • Breit, T.1    Wolvers-Tettero, I.L.M.2    Hählen, K.3
  • 60
    • 0024438573 scopus 로고
    • Detection of minimal residual disease in acute lymphoblastic leukemia by in vitro amplification of rearranged T-cell receptor δ chain sequences
    • Hansen-Hagge T.E. Yokota S. Bartram C.R. Detection of minimal residual disease in acute lymphoblastic leukemia by in vitro amplification of rearranged T-cell receptor δ chain sequences Blood 74 1989 1762 1767
    • (1989) Blood , vol.74 , pp. 1762-1767
    • Hansen-Hagge, T.E.1    Yokota, S.2    Bartram, C.R.3
  • 61
    • 0025893143 scopus 로고
    • Detection of T-cell receptor γ chain V gene rearrangements using the polymrase chain reaction: Application to the study of clonal disease cells in acute lymphoblastic leukemia
    • Taylor J.J. Rowe D. Williamson I.K. Detection of T-cell receptor γ chain V gene rearrangements using the polymrase chain reaction: Application to the study of clonal disease cells in acute lymphoblastic leukemia Blood 77 1991 1989 1995
    • (1991) Blood , vol.77 , pp. 1989-1995
    • Taylor, J.J.1    Rowe, D.2    Williamson, I.K.3
  • 62
    • 0025201139 scopus 로고
    • Detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin hypervariable region specific oligonucleotide probes
    • Jonsson O.G. Kitchens R.L. Scott F.C. Graham-Smith R. Detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin hypervariable region specific oligonucleotide probes Blood 76 1990 2072 2079
    • (1990) Blood , vol.76 , pp. 2072-2079
    • Jonsson, O.G.1    Kitchens, R.L.2    Scott, F.C.3    Graham-Smith, R.4
  • 63
    • 0024535266 scopus 로고
    • In vitro amplification of T-cell γ gene rearrangements: A new tool for the assessment of minimal residual disease in acute lymphoblastic leukemias
    • D'Auriol L. Macintyre E. Galibert F. Sigaux F. In vitro amplification of T-cell γ gene rearrangements: A new tool for the assessment of minimal residual disease in acute lymphoblastic leukemias Leukemia 3 1989 155 158
    • (1989) Leukemia , vol.3 , pp. 155-158
    • D'Auriol, L.1    Macintyre, E.2    Galibert, F.3    Sigaux, F.4
  • 64
    • 0026539151 scopus 로고
    • Minimal residual disease in childhood acute lymphoblastic leukemia: Analysis of patients in continuous complete remission or with consecutive relapse
    • Biondi A. Yokota S. Hansen-Hagge T.E. Minimal residual disease in childhood acute lymphoblastic leukemia: Analysis of patients in continuous complete remission or with consecutive relapse Leukemia 6 1992 282 288
    • (1992) Leukemia , vol.6 , pp. 282-288
    • Biondi, A.1    Yokota, S.2    Hansen-Hagge, T.E.3
  • 65
    • 0027976273 scopus 로고
    • Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction
    • Brisco M.J. Concon J. Hughes E. Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction Lancet 343 1994 196 200
    • (1994) Lancet , vol.343 , pp. 196-200
    • Brisco, M.J.1    Concon, J.2    Hughes, E.3
  • 66
    • 0026606861 scopus 로고
    • Detection of minimal residual disease in acute leukemia by immunological marker analysis and polymerase chain reaction
    • van Dongen J.J.M. Breit T. Adriaansen H.J. Detection of minimal residual disease in acute leukemia by immunological marker analysis and polymerase chain reaction Leukemia 6 Suppl 1 1992 47 59
    • (1992) Leukemia , vol.6 , Issue.Suppl 1 , pp. 47-59
    • van Dongen, J.J.M.1    Breit, T.2    Adriaansen, H.J.3
  • 67
    • 0025880325 scopus 로고
    • Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin
    • Beishuizen A. Hählen K. Hagemeijer A. Multiple rearranged immunoglobulin genes in childhood acute lymphoblastic leukemia of precursor B-cell origin Leukemia 5 1991 657 667
    • (1991) Leukemia , vol.5 , pp. 657-667
    • Beishuizen, A.1    Hählen, K.2    Hagemeijer, A.3
  • 68
    • 0026327554 scopus 로고
    • Extensive junctional diversity of γδ T-cell receptors expressed by T-cell acute lymphoblastic leukemias: Implications for the detection of minimal residual disease
    • Breit T.M. Wilvers-Tettero I.L.M. Hahlen K. Extensive junctional diversity of γδ T-cell receptors expressed by T-cell acute lymphoblastic leukemias: Implications for the detection of minimal residual disease Leukemia 5 1991 1076 1086
    • (1991) Leukemia , vol.5 , pp. 1076-1086
    • Breit, T.M.1    Wilvers-Tettero, I.L.M.2    Hahlen, K.3
  • 69
    • 0027259409 scopus 로고
    • Clonal evolution in acute myeloid leukemia
    • Busque L. Gilliland D.G. Clonal evolution in acute myeloid leukemia Blood 82 1993 337 342
    • (1993) Blood , vol.82 , pp. 337-342
    • Busque, L.1    Gilliland, D.G.2
  • 70
    • 0028244595 scopus 로고
    • Sequential relapses of blast crisis may involve different clones of cells with different molecular abnormalities
    • Foti A. Cline M.J. Sequential relapses of blast crisis may involve different clones of cells with different molecular abnormalities Br J Haematol 87 1994 627 630
    • (1994) Br J Haematol , vol.87 , pp. 627-630
    • Foti, A.1    Cline, M.J.2
  • 71
    • 0021799232 scopus 로고
    • Frequent biclonality and Ig gene alterations among B cell lymphomas that show multiple histologic forms
    • Siegelman M.H. Cleary M.L. Warnke R. Frequent biclonality and Ig gene alterations among B cell lymphomas that show multiple histologic forms J Exp Med 161 1985 850 863
    • (1985) J Exp Med , vol.161 , pp. 850-863
    • Siegelman, M.H.1    Cleary, M.L.2    Warnke, R.3
  • 72
    • 0028144470 scopus 로고
    • Characteristion of non-concordance in the T-cell receptor γ chain genes at presentation and clinical relapse in acute lymphoblastic leukemia
    • Taylor J.J. Rowe D. Kylefjord H. Characteristion of non-concordance in the T-cell receptor γ chain genes at presentation and clinical relapse in acute lymphoblastic leukemia Leukemia 8 1994 60 66
    • (1994) Leukemia , vol.8 , pp. 60-66
    • Taylor, J.J.1    Rowe, D.2    Kylefjord, H.3
  • 73
    • 0027217984 scopus 로고
    • Analysis of rearranged immunoglobulin genes indicating a process of clonal evolution in chronic lymphocytic leukaemia
    • Hakim I. Rechavi G. Brok-Simoni F. Analysis of rearranged immunoglobulin genes indicating a process of clonal evolution in chronic lymphocytic leukaemia Br J Haematol 84 1993 436 442
    • (1993) Br J Haematol , vol.84 , pp. 436-442
    • Hakim, I.1    Rechavi, G.2    Brok-Simoni, F.3
  • 74
    • 0022540466 scopus 로고
    • Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B-cell lymphoma
    • Cleary M.L. Meeker T.C. Levy S. Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B-cell lymphoma Cell 44 1986 97 106
    • (1986) Cell , vol.44 , pp. 97-106
    • Cleary, M.L.1    Meeker, T.C.2    Levy, S.3
  • 75
    • 0025745446 scopus 로고
    • The role of clonal selection in the pathogenesis of an autoreactie human B-cell lymphoma
    • Friedman D.F. Cho E.A. Goldman J. The role of clonal selection in the pathogenesis of an autoreactie human B-cell lymphoma J Exp Med 174 1991 525 537
    • (1991) J Exp Med , vol.174 , pp. 525-537
    • Friedman, D.F.1    Cho, E.A.2    Goldman, J.3
  • 76
    • 0023195712 scopus 로고
    • Retention of an idiotypic determinant in a human B-cell lymphoma undergoing immunoglobulin variable-region mutation
    • Kon S. Levy S. Levy R. Retention of an idiotypic determinant in a human B-cell lymphoma undergoing immunoglobulin variable-region mutation Proc Natl Acad Sci 84 1987 5053 5057
    • (1987) Proc Natl Acad Sci , vol.84 , pp. 5053-5057
    • Kon, S.1    Levy, S.2    Levy, R.3
  • 77
    • 0023838005 scopus 로고
    • Single cell origin of bigenotypic and biphenotypic B-cell proliferations in human follicular lymphomas
    • Cleary M.L. Galili N. Trela M. Single cell origin of bigenotypic and biphenotypic B-cell proliferations in human follicular lymphomas J Exp Med 167 1988 582 597
    • (1988) J Exp Med , vol.167 , pp. 582-597
    • Cleary, M.L.1    Galili, N.2    Trela, M.3
  • 78
    • 0025957456 scopus 로고
    • Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B-cell
    • Zelenetz A.D. Chen T.T. Levy R. Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B-cell J Exp Med 173 1991 197 207
    • (1991) J Exp Med , vol.173 , pp. 197-207
    • Zelenetz, A.D.1    Chen, T.T.2    Levy, R.3
  • 79
    • 0028341604 scopus 로고
    • Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes
    • Zhu D. Hawkins R.E. Hamblin T.J. Stevenson F.K. Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes Br J Haematol 86 1994 505 512
    • (1994) Br J Haematol , vol.86 , pp. 505-512
    • Zhu, D.1    Hawkins, R.E.2    Hamblin, T.J.3    Stevenson, F.K.4
  • 80
    • 0025834564 scopus 로고
    • Emergence of a B-cell lymphoblastic lymphoma in a patient with B-cell chronic lymphocytic leukemia: Evidence for the single-cell origin of the two tumors
    • Pistoia V. Roncella S. Di Celle P.F. Emergence of a B-cell lymphoblastic lymphoma in a patient with B-cell chronic lymphocytic leukemia: Evidence for the single-cell origin of the two tumors Blood 78 1991 797 804
    • (1991) Blood , vol.78 , pp. 797-804
    • Pistoia, V.1    Roncella, S.2    Di Celle, P.F.3
  • 81
    • 0029144480 scopus 로고
    • Clonal relationship between lymphocytic predominance Hodgkin's disease and concurrent or subsequent large-cell lymphoma of B lineage
    • Wickert R.S. Weisenburger D.D. Tierens A. Clonal relationship between lymphocytic predominance Hodgkin's disease and concurrent or subsequent large-cell lymphoma of B lineage Blood 86 1995 2312 2320
    • (1995) Blood , vol.86 , pp. 2312-2320
    • Wickert, R.S.1    Weisenburger, D.D.2    Tierens, A.3
  • 82
    • 0026569818 scopus 로고
    • Clonal expansion of p53 mutant cells is associated with brain tumour progression
    • Sidransky D. Mikkelsen T. Schwechheimer K. Clonal expansion of p53 mutant cells is associated with brain tumour progression Nature 355 1992 846 847
    • (1992) Nature , vol.355 , pp. 846-847
    • Sidransky, D.1    Mikkelsen, T.2    Schwechheimer, K.3
  • 83
    • 0026547577 scopus 로고
    • p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression
    • Fults D. Brockmeyer D. Tullous M.W. p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression Cancer Res 52 1992 674 679
    • (1992) Cancer Res , vol.52 , pp. 674-679
    • Fults, D.1    Brockmeyer, D.2    Tullous, M.W.3
  • 84
    • 0026531917 scopus 로고
    • Molecular characterization of areas with low grade rumor or satellitosis in human malignant astrocytomas
    • Leenstra S. Troost D. Westerveld A. Molecular characterization of areas with low grade rumor or satellitosis in human malignant astrocytomas Cancer Res 52 1992 1568 1572
    • (1992) Cancer Res , vol.52 , pp. 1568-1572
    • Leenstra, S.1    Troost, D.2    Westerveld, A.3
  • 85
    • 0026036415 scopus 로고
    • The polymerase chain reaction: A new tool for the detection of minimal residual disease in haematological malignancies
    • Fey M.F. Kulozik A.E. Hansen-Hagge T.E. Tobler A. The polymerase chain reaction: A new tool for the detection of minimal residual disease in haematological malignancies Eur J Cancer 27 1991 89 94
    • (1991) Eur J Cancer , vol.27 , pp. 89-94
    • Fey, M.F.1    Kulozik, A.E.2    Hansen-Hagge, T.E.3    Tobler, A.4
  • 86
    • 0025948987 scopus 로고
    • Cancer diagnosis by molecular genetic probes: The present and the promise
    • Fey M.F. Tobler A. Cancer diagnosis by molecular genetic probes: The present and the promise Ann Oncol 2 1991 629 633
    • (1991) Ann Oncol , vol.2 , pp. 629-633
    • Fey, M.F.1    Tobler, A.2
  • 87
    • 0028127956 scopus 로고
    • New directions in molecular medicine
    • Karp J.E. Broder S. New directions in molecular medicine Cancer Res 54 1994 653 665
    • (1994) Cancer Res , vol.54 , pp. 653-665
    • Karp, J.E.1    Broder, S.2
  • 88
    • 0028915222 scopus 로고
    • Molecular foundations of cancer: New targets for intervention
    • Karp J.E. Broder S. Molecular foundations of cancer: New targets for intervention Nature Med 1 1995 309 320
    • (1995) Nature Med , vol.1 , pp. 309-320
    • Karp, J.E.1    Broder, S.2


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