Synthesis of 2-phenylbenzofuran derivatives as testosterone 5α- reductase inhibitor

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 2, 1999, Pages 226-240

  Ishibashi, Koki ^a   Nakajima, Katsuyoshi ^a   Sugioka, Yuki ^a   Sugiyama, Mitsuo ^a   Hamada, Takakazu ^b   Horikoshi, Hiroyoshi ^b   Nishi, Takahide ^a  

^a Medicinal Chemistry Research Laboratories   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

2 phenylbenzofuran; Benign prostatic hyperplasia; Testosterone 5 reductase inhibitor

Indexed keywords

4 [2 [5 [N (4,4' DIMETHOXYDIPHENYLMETHYL)AMINO]BENZO[B]FURAN 2 YL]PHENYLOXY]BUTYRIC ACID; 4 [2 [6 (N DIPHENYLMETHYLAMINO)BENZO[B]FURAN 2 YL]BUTYRIC ACID; STEROID 5ALPHA REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HORMONE INHIBITION; HUMAN; NONHUMAN; PROSTATE HYPERTROPHY; STRUCTURE ACTIVITY RELATION;

EID: 0032963632     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.226     Document Type: Article

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