Synthesis and testosterone 5α-reductase-inhibitory activity of 4-aza-5α-androstane-17-carboxamide compound with an aromatic moiety in the C-17 carbamoyl group

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 1, 1996, Pages 115-121

  Kurata, Hitoshi ^a   Ishibashi, Koki ^a   Saito, Shinichi ^a   Hamada, Takakazu ^a   Horikoshi, Hiroyoshi ^a   Furukawa, Yoji ^a   Kojima, Koichi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

4 aza 5 androstane; Prostatic hypertrophy; Steroid; Synthesis; Testosterone 5 reductase inhibitor

Indexed keywords

4 AZA 5ALPHA ANDROSTANE 17 CARBOXAMIDE DERIVATIVE; FINASTERIDE; STEROID 5ALPHA REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG CONFORMATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; NONHUMAN; PROSTATE HYPERTROPHY; RAT; STRUCTURE ACTIVITY RELATION; TESTOSTERONE SYNTHESIS;

ANDROSTANES; ANIMALS; AZA COMPOUNDS; ENZYME INHIBITORS; HUMANS; MALE; PROSTATE; RATS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 0030019620     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.115     Document Type: Article

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