Vitamin D receptor translation initiation codon polymorphism and markers of osteoporotic risk in older African-American women

Osteoporosis International

Volumn 9, Issue 3, 1999, Pages 214-219

  Zmuda, Joseph M ^a   Cauley, J A ^a   Danielson, M E ^a   Theobald, T M ^b   Ferrell, R E ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

African Americans; Bone mineral density; Genetics; Osteoporosis; Vitamin D receptor

Indexed keywords

CALCIUM; VITAMIN D RECEPTOR;

AGED; ARTICLE; BONE DENSITY; CALCIUM ABSORPTION; DNA POLYMORPHISM; FEMALE; GENOTYPE; HETEROZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; NEGRO; OSTEOPOROSIS; PRIORITY JOURNAL; RISK; START CODON;

AFRICAN CONTINENTAL ANCESTRY GROUP; AGED; BONE DENSITY; CALCANEUS; CODON, INITIATOR; FEMALE; GENOTYPE; HIP; HUMANS; OSTEOPOROSIS, POSTMENOPAUSAL; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL;

EID: 0032960207     PISSN: 0937941X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001980050139     Document Type: Article

References (35)

1. Griffin MR, Ray WA, Fought RL, Melton LJ. Black-white differences in fracture rates. Am J Epidemiol 1992;136:1378-85.
2. Maggi S, Kelsey JL, Litvak J, Heyse SP. Incidence of hip fractures in the elderly: a cross-national study. Osteoporos Int 1991;1:232-41.
3. Cauley JA, Gutai JP, Kuller LH, Scott J, Nevitt MC. Black-white differences in serum sex hormones and bone mineral density. Am J Epidemiol 1994;139:1035-46.
4. Cummings SR, Cauley JA, Palermo L, et al. Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int 1994;4:226-9.
5. Theobald TM, Cauley JA, Gluer CC, Bunker CH, Genant HK, Black-white differences in hip geometry. Osteoporos Int 1998;8:61-7.
6. Luckey MM, Wallenstein S, Lapinski R, Meier DE. A prospective study of bone loss in African-American and white women: a clinical research center study. J Clin Endocrinol Metab 1996;81:2948-56.
7. Bell NH, Shary J, Stevens J, Garza M, Gordon L, Edwards J. Demonstration that bone mass is greater in black than in white children. J Bone Miner Res 1991;6:719-23.
8. Ettinger B, Sidney S, Cummings SR, et al. Racial differences in bone density between young adult black and white subjects persist after adjustment for anthropometric, lifestyle, and biochemical differences. J Clin Endocrinol Metab 1997;82:429-34.
9. Morrison N. Vitamin D receptor gene variants and osteoporosis: A contributor to the polygenic control of bone density. In: Feldman D, Glorieux FH, Pike JW, editors. Vitamin D. San Diego: Academic Press, 1997;713-31.
10. Baker AR, McDonnell DP, Hughes M. et al. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci USA 1988;85:3294-8.
11. Gross C, Eccleshall TR, Malloy PJ. Villa ML, Marcus R, Feldman D. The presence of a polymorphism at the translation initiation site of the vitamin D receptor gene is associated with low bone mineral density in postmenopausal Mexican-American women. J Bone Miner Res 1996;11:1850-5.
12. Arai H, Miyamoto KI, Taketani Y, et al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res 1997;12:915-21.
13. Harris SS, Eccleshall TR,. Gross C, Dawson-Hughes B, Feldman D. The vitamin D receptor start codon polymorphism (FokI) and bone mineral density in premenopausal American black and white women. J Bone Miner Res 1997;12:1043-8.
14. Cauley JA. Danielson ME, Gregg EW, Vogt MT, Zmuda J, Bauer DC. Calcaneal ultrasound attenuation in older African-American and Caucasian-American women. Osteoporos Int 1997;7:100-4.
15. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215-9.
16. Zmuda JM, Cauley JA, Danielson ME, Wolf RL, Ferrell RE. Vitamin D receptor gene polymorphisms, bone turnover, and rates of bone loss in older African-American women. J Bone Miner Res 1997;12:1446-52.
17. Steiger P, Cummings SR, Black DM, Spencer NE, Genant HK. Age-related decrements in bone mineral density in women over 65. J Bone Miner Res 1992;7:625-32.
18. Gluer CC, Cummings SR, Pressman A, et al. Prediction of hip fractures from pelvic radiographs: the study of osteoporotic fractures. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res 1994;9:671-7.
19. Heaney RP, Recker RR. Estimation of true calcium absorption. Ann Intern Med 1985;103:516-21.
20. Heaney RP, Recker RR. Estimating true fractional calcium absoiption. Ann Intern Med 1988;106:905-6.
21. Cummings SR, Block G, McHenry K, Baron RB. Evaluation of two food frequency methods of measuring dietary calcium intake. Am J Epidemiol 1987;126:796-802.
22. Eccleshall TR, Garnero P, Gross C, Delmas PD, Feldman D. Lack of correlation between start codon polymorphism of the vitamin D receptor gene and bone mineral density in premenopausal French women: the OFELY study. J Bone Miner Res 1998;13:31-5.
23. Geusens P. Geometric characteristics of the proximal femur and hip fracture risk. Osteoporos Int 1996; Suppl 3:827-30.
24. Gluer CC, Wu CY, Genant HK. Broadband ultrasound attenuation signals depend on trabecular orientation: an in vitro study. Osteoporos Int 1993;3:185-91.
25. Gluer CC, Wu CY, Jergas M, Goldstein SA, Genant HK. Three quantitative ultrasound parameters reflect bone structure. Calcif Tissue Int 1994;55:46-52.
26. Bauer DC, Gluer CC, Cauley JA, et al. Broadband ultrasound attenuation predicts fractures strongly and independently of densitometry in older women: a prospective study. Arch Intern Med 1997;157:629-34.
27. Bauer DC, Gluer CC, Genant HK, Stone K. Quantitative ultrasound and vertebral fracture in postmenopausal women. Fracture Intervention Trial Research Group. J Bone Miner Res 1995;10:353-8.
28. Faulkner KG, Cummings SR, Black D, Palermo L, Gluer CC, Genant HK. Simple measurement of femoral geometry predicts hip fracture: the study of osteoporotic fractures. J Bone Miner Res 1993;8:1211-7.
29. Arden NK, Baker J, Hogg C, Baan K, Spector TD. The heritability of bone mineral density, ultrasound of the calcaneus and hip axis length: a study of postmenopausal twins. J Bone Miner Res 1996;11:530-4.
30. Danielson ME, Cauley JA, Zmuda JM, Ngo D, Charron M, Heaney RP. Fractional calcium absorption is correlated in mothers and daughters. J Bone Miner Res 1997; 12 (Suppl 1):S555.
31. Dawson-Hughes B, Harris SS, Finneran S. Calcium absorption on high and low calcium intakes in relation to vitamin D receptor genotype. J Clin Endocrinol Metab 1995;80:3657-61.
32. Wishart JM, Horowitz M, Need AG, et al. Relations between calcium intake, calcitriol, polymorphisms of the vitamin D receptor gene, and calcium absorption in premenopausal women. Am J Clin Nutr 1997;65:798-802.
33. Francis RM, Harrington F, Turner E, Papiha SS, Datta HK. Vitamin D receptor gene polymorphism in men and its effect on bone density and calcium absorption. Clin Endocrinol 1997; 46:83-6.
34. Kinyamu HK, Gallagher JC, Knezetic JA, DeLuca HF, Prahl JM, Lanspa SJ. Effect of vitamin D receptor genotypes on calcium absorption, duodenal vitamin D receptor concentration, and serum 1,25-dihydroxyvitamin D levels in normal women. Calcif Tissue Int 1997;60:491-5.
35. Zmuda JM, Cauley JA, Ensrud KE, Heaney RP, Eisman JA, Cummings SR. Vitamin D receptor gene polymorphisms and fractional calcium absorption in older women. J Bone Miner Res 1997; 12 (Suppl I):S371.