Current status of liquid ventilation

Current Opinion in Pediatrics

Volumn 11, Issue 2, 1999, Pages 126-132

  Weis, Carla M ^a   Fox, William W ^a  

^a PENNSYLVANIA HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PERFLUORO COMPOUND;

ANTIINFLAMMATORY ACTIVITY; ARTIFICIAL VENTILATION; ASPIRATION PNEUMONIA; CLINICAL TRIAL; CONGENITAL DIAPHRAGM HERNIA; DRUG UPTAKE; GAS EXCHANGE; HUMAN; INSPIRATORY CAPACITY; LUNG MECHANICS; MAJOR CLINICAL STUDY; META ANALYSIS; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEWBORN; PATIENT CARE; PRESCHOOL CHILD; PRIORITY JOURNAL; REGIONAL PERFUSION; RESPIRATORY DISTRESS; REVIEW;

ANIMALS; ANIMALS, NEWBORN; CLINICAL TRIALS; EVALUATION STUDIES; FLUOROCARBONS; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; RESPIRATION DISORDERS; RESPIRATION, ARTIFICIAL;

EID: 0032959745     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008480-199904000-00005     Document Type: Review

References (66)

1. 1 Shaffer TH, Rubenstein D, Moskowitz D, Delivoria-Papadopoulos M: Gaseous exchange and acid-base balance in premature lambs during liquid ventilation since birth. Pediatr Res 1976, 10:227-231.
2. 2 Wolfson MR, Shaffer TH: Liquid ventilation during early development: theory, physiologic processes and application. J Develop Physiol 1990, 13:1-12.
3. 3 Wolfson MR, Greenspan JS, Deoras KS, Rubenstein SD, Shaffer TH: Comparison of gas and liquid ventilation: clinical, physiological, and histological correlates. J Applied Physiol 1992, 72:1024-1031.
4. 4 Stavis RL, Wolfson MR, Cox CA, Kechner N, Shaffer TH: Physiologic, biochemical, and histologic correlates associated with tidal liquid ventilation. Pediatr Res 1998, 43:132-138. This well excecuted and well presented study demonstrates successful use of total liquid ventilation for 24 hours in the premature lamb, including PFC systemic uptake data.
5. 5 Leach CL, Fuhrman BP, Morin FC, Rath MG: Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: A prospective, randomized, controlled study. Crit Care Med 1993, 21:1270-1278.
6. 6 Wilcox DT, Glick PL, Karamanoukian HL, Morin FC, Fuhrman BP, Leach CL: Perfluorocarbon associated gas exchange (PAGE) and nitric oxide in the lamb with congenital diaphragmatic hernia model [abstract]. Pediatr Res 1994, 35:A260.
7. th Annual Meeting of the Children's National Medical Center; 1994; Keystone, CO.
8. 8 Wolfson MR, Kechner NE, Friss H, Rubenstein SD, Shaffer TH: Improved gas exchange during and following slow tracheal instillation of perfluorochemical liquid in neonatal respiratory distress [abstract]. Am J Respir Crit Care Med 1994, 149:A545.
9. 9 Leach CL, Greenspan JS, Rubenstein SD, Shaffer TH, Wolfson MR, Jackson JC, et al.: Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. N Engl J Med 1996, 335:761-767.
10. 10 Hirschl RB, Pranikoff T, Gauger P, Schreiner RJ, Dechert R, Bartlett RH: Liquid ventilation in adults, children and neonates. Lancet 1995, 346:1201-1202.
11. 11 Greenspan JS, Fox WW, Rubenstein SD, Wolfson MR, Spinner SS, Shaffer TH, the Philadelphia Liquid Ventilation Consortium: Partial liquid ventilation in critically ill infants receiving extracorporeal life support. Pediatrics 1997, 99:1-5. Available at: http://www.pediatrics.org/cgi/content/full/99/1/e2.
12. 12 Leach CL, Fox WW, Greenspan JS, Backstrom J, LiquiVent Study Group: Serial filling and evaporative patterns of chest radiographs in term and preterm neonates treated with partial liquid ventilation with perflubron [abstract]. Pediatr Res 1997, 258A.
13. 13 Fox WW, Greenspan JS, Hirschl R, Leach CL, Wolfson MR, Shaffer TH, the LiquiVent Study Group: Alveolar recruitment during and after tracheal instillation of LiquiVent in infants on partial liquid ventilation [abstract]. Pediatr Res 1997, 253A.
14. 14 Weis CM, Wolfson MR, Shaffer TH: Liquid-assisted ventilation: Physiology and clinical application. Ann Med 1997, 29:509-517. This is an excellent and detailed review of liquid-assisted ventilation, especially with regard to application for specific pathophysiology as well as alternative applications.
15. 15 Overbeck MC, Pranikoff T, Hirschl RB. Partial liquid ventilation provides effective gas exchange in a large animal model. J Crit Care 1996, 11:37-42.
16. 16 Tutuncu AS, Houmes RJ, Bos JA, Wollmer P, Lachmann B: Evaluation of lung function after intratracheal perfluorocarbon administration in healthy animals. Crit Care Med 1996, 24:274-279.
17. 17 Fox WW, Cox CA, Weis CM, Wolfson MR, Shaffer TH: Comparison of perfluorochemical fluids used for liquid ventilation: Effect of endotracheal tube flow resistance. Pediatr Pulmonol 1997, 23:449-456.
18. 18 Shaffer TH, Tran N, Bhutani VK, Sivieri EM: Cardiopulmonary function in very preterm lambs during liquid ventilation. Pediatr Res 1983, 17:680-684.
19. 19 Shaffer TH, Greenspan JS, Wolfson MR: Liquid Ventilation. In: New Therapies for Neonatal Respiratory Failure: a Physiological Approach. Edited by Boynton BR, Carlo WA, Jobe AH. New York: Cambridge University Press; 1994:279-301.
20. 20 Wolfson MR, Kechner NE, Roache RF, DeChadarevian JP, Friss HE, Rubenstein SD, et al.: Perfluorochemical rescue of surfactant treated premature lambs: effect of perflubron dose and ventilatory frequency. J Appl Physiol 1998, 84:624-640. This high quality study demonstrates that improvement in the premature lamb model of RDS pretreated with surfactant was directly related to PFC dose and breathing frequency during PLV. Solid physiologic and histologic data are presented.
21. 21 Weis C, Fox WW, Philips CM, Roache RF, Wolfson MR, Shaffer TH: Perfluorochemical (PFC) evaporation from the lungs: effect of initial dose [abstract]. Pediatr Res 1998, 43:302A.
22. 22 Tarczy-Hornoch T, Hildebrandt J, Mates EA, Standaert TA, Lamm WJ, Hodson WA, Jackson JC: Effects of exogenous surfactant on lung pressure-volume characteristics during liquid ventilation. J Appl Physiol 1996, 80:1764-1771.
23. 23 Steinhorn DM, Leach CL, Fuhrman BP, Holm BA: Partial liquid ventilation enhances surfactant phospholipid production. Crit Care Med 1996, 24:1252-1256.
24. 24 Tarczy-Hornoch P, Hildebrandt J, Standaert TA, Jackson JC: Surfactant replacement increases compliance in premature lamb lungs during partial liquid ventilation in situ. J Appl Physiol 1998, 84:1316-1322.
25. 25 Leach CL, Holm B, Morin FC 3rd, Fuhrman BP, Papo MC, Steinhorn D, Hernan LJ: Partial liquid ventilation in premature lambs with respiratory distress syndrome: Efficacy and compatibility with exogenous surfactant. J Pediatr 1995, 126:412-420.
26. 26 Antunes MJ, Cleary GM, Greenspan JS, Spitzer AR, Chander A: Interactions between perfluorchemicals and lung surfactant: extraction of SP-B [abstract]. Pediatr Res 1997, 41:136A.
27. 27 Kim JN, Lee C, Park MS, Namgung R, Park KI, Han DG: Improved surface active properties of perflurocarbon and exogenous pulmonary surfactant mixtures [abstract]. Pediatr Res 1997, 41:303A.
28. 28 Sukumar M, Bommaraju M, Fisher JE, Morin FC 3rd, Papo MC, Fuhrman BP, et al.: High-frequency partial liquid ventilation in respiratory distress syndrome: hemodynamics and gas exchange. J Appl Physiol 1998, 84:327-334.
29. 29 Valls-i-Soler A, Wolfson MR, Kechner N, Foust R, Shaffer TH: Comparison of natural surfactant and brief liquid ventilation rescue treatment in very immature lambs. Clinical and physiological correlates. Biol Neonate 1996, 69:275-283.
30. 30 Foust R 3rd, Tran NN, Cox C, Miller TF Jr, Greenspan JS, Wolfson MR, Shaffer TH: Liquid assisted ventilation: an alternative ventilatory strategy for acute meconium aspiration injury. Pediatr Pulm 1996, 21:316-322.
31. 31 Mrozek JD, Smith KM, Bing DR, Meyers PA, Simonton SC, Connett JE, Mammel MC: Exogenous surfactant and partial liquid ventilation: physiologic and pathologic effects. Am J Respir Crit Care Med 1997, 156:1058-1065.
32. 32 Baden HP, Mellema JD, Bratton SL, O'Rourke PP, Jackson JC: High-frequency oscillatory ventilation with partial liquid ventilation in a model of acute respiratory failure. Crit Care Med 1997, 25:299-302.
33. 33 Smith KM, Bing DR, Meyers PA, Connett JE, Boros SJ, Mammel MC: Partial liquid ventilation: a comparison using conventional and high-frequency techniques in an animal model of acute respiratory failure. Crit Care Med 1997, 25:1179-1186.
34. 34 Mrozek JE, Bing DR, Meyers PA, Connett JE, Mammel MC: High-frequency oscillation after surfactant and perflurocarbon in an animal model of RDS [abstract]. Pediatr Res 1997, 41:261A.
35. 35 Smith KM, Mrozek JD, Simonton SC, Bing DR, Meyers PA, Connett JE, Mammel MC: Prolonged partial liquid ventilation using conventional and high-frequency ventilatory techniques: gas exchange and lung pathology in an animal model of respiratory distress syndrome. Crit Care Med 1997, 25:1888-1897.
36. 36 Miller TF, Milestone B, Stern R, Shaffer TH, Wolfson MR: Effect of perfluorochemical properties on PFC distribution, elimination, and lung mechanics during partial liquid ventilation [abstract]. Am J Resp Crit Care 1998, 157:A462.
37. 37 Bateman ST, Doctor A, Price BW, Murphy MA, Bhargave N, Taylor G, et al.: Optimizing intrapulmonary perfluorocarbon: dosing method and mode of ventilation [abstract]. Pediatr Res 1998, 43:34A.
38. 38 Shaffer TH, Foust RF, Wolfson MR, Miller TF: Analysis of perfluorochemical elimination from the respiratory system. J Appl Physiol 1997, 83:1033-1040.
39. 39 Miller TF, Cox C, Roache R, Foust R 3rd, Kechner NE, Schaffer TH, et al.: The longitudinal course of perfluorochemical intrapulmonary distribution, uptake, and elimination in a chronic rabbit model [abstract]. Pediatr Res 1997, 260A.
40. 40 Stavis RL, Wolfson MR, Cox CA, Foust R, Miller TF, Kechner NE, et al.: Prolonged total liquid ventilation in premature lambs [abstract]. Ped Res 1997, 180A.
41. 41 Major D, Cadenas M, Cloutier R, Fourier L, Shaffer TH, Wolfson MR: Combined ventilation and perfluorochemical (PFC) tracheal instillation as alternative treatment for near death congenital diaphragmatic hernia. J Pediatr Surg 1995, 30:1178-1182.
42. 42 Papo MC, Paczan PR, Fuhrman BP, Steinhorn DM, Hernan LJ, Leach CL, et al.: Perfluorocarbon-associated gas exchange improves oxygenation, lung mechanics, and survival in a model of adult respiratory distress syndrome. Crit Care Med 1996, 24:466-474.
43. 43 Hirschl RB, Tooley R, Parent A, Johnson K, Bartlett RH: Evaluation of gas exchange, pulmonary compliance, and lung injury during total and partial liquid ventilation in the acute respiratory distress syndrome. Crit Care Med 1996, 24:1001-1008.
44. 44 Foust R, Tran NN, Cox C, Miller TF Jr., Greenspan JS, Wolfson MR, et al.: Liquid-assisted ventilation: An alternative ventilatory strategy for acute meconium aspiration injury. Pediatr Pulmonol 1996, 21:316-322.
45. 45 Fox WW, Weis C, Cox C, Farina C, Drott H, Wolfson MR, Shaffer TH: Pulmonary administration of gentamicin during liquid ventilation in a newborn lamb lung injury model. J Pediatr 1997, 100:1-7. Available at: http://www.pediatrics.org/cgi/content/full/100/5/e5.
46. 46 Cox CA, Cullen AB, Wolfson MR, Harris K, Hipp S, Roache R, Shaffer TH: Intratrachael (IT) delivery of a nanocrystal gentamicin/perflurochemical (G/PFC) suspension in normal (N) and injured (I) lungs [abstract]. Pediatr Res 1998, 43:245A.
47. 47 Wolfson MR, Greenspan JS, Shaffer TH: Pulmonary administration of vasoactive drugs (PAD) by perfluorocarbon liquid ventilation. Pediatrics 1996, 97:449-455.
48. 48 Weis C, Fox WW, Cox C, Wolfson MR, Shaffer TH: Selective pulmonary vasodilation and pulmonary distribution of radiolabeled histamine during liquid ventilation (LV) in hypoxic newborn (NB) lambs [abstract]. Pediatr Res 1996, 39:392A.
49. 49 Wilcox DT, Glick PL, Karamanoukian HL, Morin FC 3rd, Fuhrman BP, Leach C: Partial liquid ventilation and nitric oxide in congenital diaphragmatic hernia. J Pediatr Surg 1997, 32:1211-1215.
50. 50 Houmes RJ, Hartog A, Verbrugge SJ, Bohm S, Lachmann B: Combining partial liquid ventilation with nitric oxide to improve gas exchange in acute lung injury. Intensive Care Med 1997, 23:163-169.
51. 51 Shaffer TH, Wolfson MR, Clark LC: State-of-the-art: liquid ventilation. Pediatr Pulmonol 1992, 14:102-109.
52. 52 Stern RG, Wolfson MR, McGuckin JF, Forge JA, Shaffer TH: High-resolution computed tomographic bronchiolography using perfluoroctylbromide (PFOB): an experimental model. J Thorac Imaging 1993, 8:300-304.
53. 53 Wolfson MR, Stern RG, Kechner N, Sekins KM, Shaffer TH: Utility of a perfluorochemcial liquid for pulmonary diagnostic imaging. Artif Cells Blood Substit Immobil Biotech 1994, 22:1409-1420.
54. 54 Gross GW, Greenspan JS, Fox WW, Rubentein SD, Wolfson MR, Shaffer TH: Use of liquid ventilation with perflubron during extracorporeal membrane oxygenation: chest radiographic appearances. Radiology 1995, 194:717-720.
55. 55 Milestone BN, Miller T Jr, Wolfson MR, Stern RG, Shaffer TH: Virtual bronchoscopy with perfluoronated hydrocarbon enhancement. Acad Radiol 1997, 4:583-586.
56. 56 Curtis SE, Peek JT, Kelly DR: Partial liquid breathing with perflubron improves arterial oxygenation in acute canine lung injury. J Appl Physiol 1993, 75:2696-2702.
57. 57 Hirschl RB, Parent A, Tooley R, Shaffer T, Wolfson M, Bartlett RH: Lung management with perfluorocarbon liquid ventilation improves pulmonary function and gas exchange during extracorporeal membrane oxygenation (ECMO). Artif Cells Blood Substit Immobil Biotechnol 1994, 22:1389-1396.
58. 58 Colton DM, Hirschl RB, Johnson KJ, Til GO, Deab SB, Bartlett, RB: Neutrophil infiltration is reduced during partial liquid ventilation in the setting of lung injury. Surg Forum 1994, 45:668-670.
59. 59 Smith TM, Steinhorn DM, Thusu K, Fuhrman BP, Dandona P: Liquid Perfluorochemical decreases the in vitro production of reactive oxygen species by alveolar macrophages. Crit Care Med 1995, 23:1533-1539.
60. 60 Rotta AT, Steinhorn DM: Partial liquid ventilation (PVL) reduces pulmonary leukostasis in a model of acute lung injury (ALI) [abstract]. Pediatr Res 1997, 41:38A.
61. 61 Sajan IS, Steinhorn DM, Haase EM, Scannapieco FM: Perfluorocarbons decrease bacterial adhesion to epithelial cells [abstract]. Pediatr Res 1998, 43:42A.
62. 62 Shaffer TH, Wolfson MR, Greenspan JS, Hoffman RE, Davis SL, Clark LC Jr: Liquid ventilation in premature lambs: Uptake, biodistribution and elimination of perfluorodecalin liquid. Reprod Fertil Dev 1996, 8:409-416.
63. 63 Liu MS, Long DM: Biological deposition of perfluorooctylbromide: tracheal administration in alveolography and bronchography. Invest Radiol 1976, 11:479-485.
64. 64 Modell JH, Tham MK, Modell JG, Calderwood HW, Ruiz BC: Distribution and retention of fluorocarbon in mice and dogs after injection or liquid ventilation. Toxicol Appl Pharmacol 1973, 26:86-92.
65. 65 Calderwood HW, Ruiz BC, Tham MK, Modell JH, Saga SA, Hood CI: Residual levels and biochemical changes after ventilation with perfluorinated liquid. J Appl Physiol 1975, 39:603-607.
66. 66 Kechner NE, Shaffer TH, Wolfson MR: Influences on perfluorochemical (PFC) blood uptake: in-vitro assessment [abstract]. Pediatr Res 1997, 41:56A.