Partial liquid ventilation enhances surfactant phospholipid production

Critical Care Medicine

Volumn 24, Issue 7, 1996, Pages 1252-1256

  Steinhorn, David M ^a,b   Leach, Corinne L ^a,b   Fuhrman, Bradley P ^a,b   Holm, Bruce A ^a,b  

^a CHILDREN S HOSPITAL OF BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

critical illness; liquid ventilation; metabolism; Perflubron; perfluorocarbon; phosphatidylcholine; phospholipid; pulmonary emergencies; surfactant

Indexed keywords

FLUOROCARBON; LUNG SURFACTANT; PERFLUOROOCTYL BROMIDE; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRITICAL ILLNESS; HYPOXIA; LUNG ALVEOLUS SURFACE TENSION; LUNG INJURY; LUNG PARENCHYMA; LUNG VENTILATION; METABOLISM; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; RABBIT;

ACUTE DISEASE; ANIMALS; FLUOROCARBONS; PHOSPHATIDYLCHOLINES; PROSPECTIVE STUDIES; PULMONARY SURFACTANTS; RABBITS; RESPIRATION, ARTIFICIAL; RESPIRATORY INSUFFICIENCY;

EID: 0029948638     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199607000-00031     Document Type: Article

References (31)

1. Fuhrman BP, Paczan PR, DeFrancisis M: Perfluorocarbon associated gas exchange. Crit Care Med 1991; 19:712-723
2. Shaffer TH, Rubenstein D, Moskowitz GD, et al: Gaseous exchange and acid-base balance in premature lambs during liquid ventilation since birth. Pediatr Res 1976; 10:227-231
3. Leach CL, Fuhrman BP, Morin FC III, et al: Perfluorocarbon-associated gas exchange (PAGE) in respiratory distress syndrome. Crit Care Med 1993; 21: 1270-1278
4. Nesti FD, Fuhrman BP, Steinhorn DM, et al: Perfluorocarbon associated gas exchange (PAGE) in gastric aspiration. Crit Care Med 1994; 22:1445-1452
5. Papo MC, Paczan PR, Burak B, et al: A medical grade perfluorocarbon used during PAGE improves oxygenation and ventilation in a model of ARDS. Abstr. Pediatr Res 1993; 33:39A
6. Leach CL, Holm B, Morin FC III, et al: Partial liquid ventilation in premature lambs with respiratory distress syndrome: Efficacy and compatibility with exogenous surfactant. J Pediatr 1995; 126:412-420
7. Wilcox D, Glick P, Karamanoukian H, et al: Pathophysiology of congenital diaphragmatic hernia XIII: Perfluorocarbon associated gas exchange (PAGE) improves pulmonary mechanics, oxygenation, and allows nitric oxide delivery in the hypoplastic lung congenital diaphragmatic hernia lamb model. Crit Care Med 1995; 23:1858-1863
8. Curtis S, Peek J: Effects of progressive intratracheal administration of perflubron during conventional gas ventilation in anesthetized dogs with oleic acid lung injury. Adv Exp Med Biol 1994; 345:51-58
9. Hirschl R, Parent A, Tooley R: Liquid ventilation improves pulmonary function, gas exchange and lung injury in a model of respiratory failure. Ann Surg 1995; 221:79-88
10. Hansen T, Corbet A: Lung development and function. In: Diseases of the Newborn. Sixth Edition. Taeusch HW, Ballard RA, Avery ME (Eds). Philadelphia, WB Saunders, 1991, p 464
11. Leach CL, Greenspan JS, Rubenstein SD, et al: Partial liquid ventilation with Liquivent: A pilot safety and efficacy study in premature newborns with severe respiratory distress syndrome (RDS). Abstr. Pediatr Res 1995; 37:220A
12. Jobe A: The labeling and biological half-life of phosphatidylcholine in subcellular fractions of rabbit lung. Biochim Biophys Acta 1977; 489:440-453
13. Lowry OH, Rosebrough NJ, Farr NJ, et al: Protein measurement with the folin reagent. J Biol Chem 1951; 193:265-275
14. Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37:911-917
15. Bartlett GR: Phosphorous assay in column chromatography. J Biol Chem 1959; 234:466-468
16. Chander A, Fisher AB: Regulation of lung surfactant secretion. Am J Physiol 1990;258:L241-L253
17. Brown LA, Longmore WJ: Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused lung and in the alveolar type II cell in culture. J Biol Chem 1981; 256:66-72
18. Oyarzun MJ, Clements JA: Control of lung surfactant by ventilation, adrenergic mediators, and prostaglandins in rabbit. Am Rev Respir Dis 1978; 117: 879-891
19. Gilfillan AM, Rooney SA: Arachadonic acid metabolites stimulate phosphatidylcholine secretion in primary culture of type II pneumocytes. Biochim Biophys Acta 1985; 833:336-341
20. Sano K, Voelker DR, Mason RJ: Effect of secretagogues on cytoplasmic free calcium in alveolar type II epithelial cells. Am J Physiol 1987; 22:C679-C686
21. Hildebran JN, Goerke J, Clements JA: Surfactant release in excised rat lung is stimulated by air inflation. J Appl Physiol 1981; 51:905-910
22. Nicholas TE, Barr HA: Control of release of surfactant phospholipids in the isolated perfused rat lung. J Appl Physiol 1981; 51:90-98
23. Nicholas TE, Barr HA: The release of surfactant in rat lung by brief periods of hyperventilation. Respir Physiol 1983; 52:69-83
24. Leach CL, Holm BA, Morin FC III, et al: Partial liquid ventilation with Liquivent increases endogenous surfactant production in premature lambs with respiratory distress syndrome. Abstr. Pediatr Res 1995; 37:220A
25. Lowe C, Shaffer T: Pulmonary vascular resistance in fluorocarbon-filled lung. J Appl Physiol 1986; 60:154-159
26. Wirtz HRW, Dobbs LC: Stretch-induced secretion of phosphatidylcholine from rat alveolar type II cells. Inhibition by surfactant protein A. In: Basic Research on Lung Surfactant. von Wichert P, Muller B (Eds). Basel, Karger, 1990, p 285
27. Smith TM, Steinhorn DM, Thusu K, et al: Liquid perfluorocarbon decreases the in vitro production of free radicals by alveolar macrophages. Crit Care Med 1995; 23:1533-1539
28. Dluzewski AR, Halsey MJ, Simmonds AC: Membrane interactions with general and local anesthetics: A review of molecular hypotheses of anesthesia. Mol Aspects Med 1983; 6:459-467
29. Miller KW: General anesthesia. In: Drugs in Anesthesia: Mechanisms of Action. London, Edward Arnold, 1987, p 133
30. Cleary GM, Antunes MJ, Greenspan JS, et al: The effect of partial liquid ventilation on surfactant metabolism in a rat model of meconium aspiration. Abstr. Pediatr Res 1995; 37:200A
31. Jobe A, Gluck L: The labeling of lung phosphatidylcholine in premature rabbits. Pediatr Res 1979; 13:635-640