An AP-2 binding sequence within exon 1 of human and porcine choline acetyltransferase genes enhances transcription in neural cells

Neuroscience

Volumn 76, Issue 3, 1996, Pages 821-827

  Baskin, F ^a   Li, Y P ^a   Hersh, L B ^b   Davis, R M ^a   Rosenberg, R N ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

AP 1; cholinergic expression; enhancer element; gene regulation; gene transcription; SP1

Indexed keywords

CHOLINE ACETYLTRANSFERASE;

ADRENERGIC NERVE CELL; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; GENE CONTROL; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER; MUTATION; NONHUMAN; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; SWINE;

EID: 0030580542     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00401-0     Document Type: Article

References (32)

1. 1. Andersson G., Pahlman S., Parrow V., Johansson I. and Hammerling U. (1994) Activation of the human NPY gene during neuroblastoma cell differentiation: transcriptional activities of AP-1 and AP-2. Cell Growth Differ. 5, 27-36.
2. 2. Andrews N. A. and Faller D. V. (1991) A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucl. Acids Res. 19, 2499.
3. 3. Bartus R. T., Dean R. L. and Lippa A. S. (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217, 408-417.
4. 4. Briggs M. R., Kadonaga J. T., Bell S. P. and Tjian R. (1986) Purification and biochemical characterization of the promotor-specific transcription factor Sp1. Science 234, 47-52.
5. 5. Buettner R., Kannan P., Imhof A., Bauer R., Yim S. O., Glockshuber R., Van Dyke M. W. and Tainsky M. A. (1993) An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2. Molec. Cell Biol. 13, 4174-4185.
6. 6. Casper D. and Davies P. (1989) Mechanism of activation of choline acetyltransferase in a human neuroblastoma cell line. Brain Res. 478, 85-94.
7. 7. Ciccarone V., Spengler B. A., Meyers M. B., Biedler J. L. and Ross R. A. (1989) Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. Cancer Res. 49, 219-225.
8. 8. Comb M. and Goodman H. (1990) CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2. Nucl. Acids Res. 18, 3975-3982.
9. 9. Courtois S. J., Lafontaine D. A., Lemaigre F. P., Durviaux S. M. and Rousseau G. G. (1990) Nuclear factor-1 and activator protein-2 bind in a mutually exclusive way to overlapping promotor sequences and trans-activate the human growth hormone gene. Nucl. Acids Res. 18, 57-64.
10. 10. Eustice D. C., Feldman P. A., Colberg-Poley A. M., Buckery R. M. and Neubauer R. H. (1991) A sensitive method for the detection of β-galactosidase in transfected mammalian cells. Biotechniques 11, 739-743.
11. 11. Faisst S. and Meyer S. (1992) Compilation of vertebrate-encoded transcription factors. Nucl. Acids Res. 20, 3-26.
12. 12. Hersh L. B., Kong C. F., Sampson C., Mues G., Li Y.-P., Fisher A., Hilt D. and Baetge E. E. (1993) Comparison of the promoter region of the human and porcine choline acetyltransferase genes: localization of an important enhancer region. J. Neurochem. 61, 306-314.
13. 13. Ibanez C. F. and Persson H. (1991) Localization of sequences determining cell type specificity and NGF responsiveness in the promoter region of the rat choline acetyltransferase gene. Eur. J. Neurosci. 3, 1309-1315.
14. 14. Inoue H., Baetge E. E. and Hersh L. B. (1993) Enhancer containing unusual GC box-like sequences on the human choline acetyltransferase gene. Molec. Brain Res. 20, 299-304.
15. 15. Kengaku M., Misawa H. and Deguchi T. (1993) Multiple mRNA species of choline acetyltransferase from rat spinal cord. Molec. Brain Res. 18, 71-76.
16. 16. Li Y.-P., Baetge E. E. and Hersh L. B. (1993) Cyclic AMP regulation of the human choline acetyltransferase gene. Neurochem. Res. 18, 271-275.
17. 17. Li Y.-P., Baskin F., Davis R. M. and Hersh L. B. (1993) Cholinergic neuron-specific expression of the human choline acetyltransferase gene is controlled by silencer elements. J. Neurochem. 61, 748-751.
18. 18. Li Y.-P., Baskin F., Davis R. M., Wu D. and Hersh L. B. (1995) A cell type-specific silencer in the human choline acetyltransferase gene requiring two distinct and interactive E boxes. Molec. Brain Res. 30, 106-114.
19. 19. Luscher B., Mitchell J., Williams T. and Tjian R. (1989) Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers. Genes Dev. 3, 1507-1517.
20. 20. Martinez H. J., Dreyfus C. F., Jonakait G. M. and Black I. B. (1987) Nerve growth factor selectively increases cholinergic markers but not neuropeptides in rat basal forebrain in culture. Brain Res. 412, 295-301.
21. 21. Matsuoka I., Mizuno N. and Kurihara K. (1989) Cholinergic differentiation of clonal rat pheochromocytoma cells (PC12) induced by retinoic acid: increase of choline acetyltransferase activity and decrease of tyrosine hydroxylase activity. Brain Res. 502, 53-60.
22. 22. Meier P., Koedood M., Philipp J., Fontana A. and Mitchell P. J. (1995) Alternative mRNAs encode multiple isoforms of transcriptional factor AP-2 during murine embryogenesis. Devl Biol. 169, 1-14.
23. 23. Misawa H., Ishii K. and Deguchi T. (1992) Gene expression of mouse choline acetyltransferase. Alternative splicing and identification of a highly active promoter region. J. biol. Chem. 267, 20392-20399.
24. 24. Mitchell P. J., Timmons P. M., Hebert J. M., Rigby P. W. J. and Tjian R. (1991) Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev. 5, 105-119.
25. 25. Mitchell P. J., Wang C. and Tjian R. (1987) Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell 50, 846-861.
26. 26. Park K. and Kim K.-H. (1993) The site of cAMP action in the insulin induction of gene expression of acetyl-CoA carboxylase is AP-2. J. biol. Chem. 268, 17811-17819.
27. 27. Price D. L. (1986) New perspectives on Alzheimer's disease. A. Rev. Neurosci. 9, 489-512.
28. 28. Quirin-Stricker C., Nappey V., Simoni P., Toussaint J. L. and Schmitt M. (1994) Trans-activation by thyroid hormone receptors of the 5′ flanking region of the human ChAT gene. Molec. Brain Res. 23, 253-265.
29. 29. Ross R. A. and Biedler J. (1985) Presence and regulation of tyrosinase activity in human neuroblastoma cell variants in vitro. Cancer Res. 45, 1628-1632.
30. 30. Williams T. and Tjian R. (1991) Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev. 5, 670-682.
31. 31. Wolffe A. P. (1994) Architectural transcription factors. Science 264, 1100-1101.
32. 32. Wu D. and Hersh L. B. (1994) Choline acetyltransferase: celebrating its fiftieth year. J. Neurochem. 62, 1653-1663.