Protein encapsulation in biodegradable amphiphilic microspheres

International Journal of Pharmaceutics

Volumn 181, Issue 2, 1999, Pages 159-172

  Bouillot, Philippe ^a   Ubrich, Nathalie ^b   Sommer, Françoise ^c   Minh Duc, Tran ^d   Loeffler, Jean Philippe ^e   Dellacherie, Edith ^a  

^a LAB DE CHIM PHYS MACROMOLECULAIRE   (France)

^b UNIVERSITÉ DE LORRAINE   (France)

^c Biophy Research   (France)

^d UNIVERSITÉ LYON 1   (France)

^e UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Adsorption; Diblock copolymers; Microspheres; MPOE PLA; Release profiles

Indexed keywords

BOVINE SERUM ALBUMIN; COPOLYMER; MICROSPHERE; POLYLACTIC ACID; PROTEIN; RHODAMINE;

ADSORPTION; ARTICLE; ATOMIC FORCE MICROSCOPY; CONFOCAL LASER MICROSCOPY; DRUG COATING; DRUG RELEASE; ENCAPSULATION; PRIORITY JOURNAL;

ADSORPTION; BIOCOMPATIBLE MATERIALS; DELAYED-ACTION PREPARATIONS; ELECTRON PROBE MICROANALYSIS; FLUORESCEIN-5-ISOTHIOCYANATE; LACTIC ACID; MICROSCOPY, CONFOCAL; MICROSPHERES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERS; SERUM ALBUMIN, BOVINE; WATER;

EID: 0032950616     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00023-X     Document Type: Article

References (32)

1. Alonso M.J., Gupta R.K., Min C., Siber G.R., Langer R. Biodegradable microspheres as controlled-release tetanus toxoid delivery systems. Vaccine. 12:1994;299-306.
2. Babak V.G., Gref R., Dellacherie E. The effect of hydrophile-lipophile balance of water-soluble poly(ethylene glycol)-poly(lactic acid) diblock copolymers on the stability of microscopic emulsion films and nanoemulsions. Mendeleev comm. 3:1998;105-107.
3. Bouillot P., Petit A., Dellacherie E. Protein encapsulation in biodegradable amphiphilic microspheres I. Polymer synthesis and characterization, and microsphere elaboration. J. Appl. Polym. Sci. 68:1998;1695-1702.
4. Boury F., Marchais H., Proust J.E., Benoit J.P. Bovine serum albumin release from poly(L-hydroxyacid) microspheres: effects of polymer molecular weight and surface properties. J. Control. Release. 45:1997;75-86.
5. Cohen S., Yoshioka T., Lucarelli M., Hwang L.H., Langer R. Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres. Pharm. Res. 8:1991;713-719.
6. Couvreur P., Puisieux F. Nano- and microparticles for the delivery of peptides and proteins. Adv. Drug Del. Rev. 5:1990;265-285.
7. Crotts G., Sah H., Park T.G. Adsorption determines in vitro protein release rate from biodegradable microspheres: quantitative analysis of surface area during degradation. J. Control. Release. 41:1997;101-111.
8. Crotts G., Park T.G. Stability and release of bovine serum albumin encapsulated within poly(D,L-lactide-co-glycolide) microparticles. J. Control. Release. 44:1997;123-134.
9. Davies M.C., Short R.D., Khan M.A., Watts J.F., Brown A., Eccles M.J., Humphrey P., Vickerman J.C., Vert M. An XPS and SIMS analysis of biodegradable biomedical polyesters. Surf. Interface Anal. 14:1989;115-120.
10. Hu D.S., Liu H.J., Pan I.L. Inhibition of bovine serum albumin adsorption by poly(ethylene glycol) soft segment in biodegradable poly(ethylene glycol)/poly(L-lactide) copolymers. J. Appl. Polym. Sci. 50:1993;1391-1396.
11. Izutsu K.I., Yoshioka S., Kojima S., Randolph T.W., Carpenter J.F. Effects of sugars and polymers on crystallisation of poly(ethylene glycol) in frozen solutions: phase separation between incompatible polymers. Pharm. Res. 13:1996;1393-1400.
12. Jeon I., Lee J.H., Andrade D., Degennes P.G. Protein surface interactions in the presence of polyethylene oxide.I. Simplified theory. J. Colloid Interface Sci. 142:1991;149-158.
13. Johnson R.E., Lanaski L.A., Gupta V., Griffin M.J., Gaud H.T., Needham T.E., Zia H. Stability of atriopeptin III in poly(D,L lactide-co-glycolide) microspheres. J. Control. Release. 17:1991;61-67.
14. Kissel T., Li Y.X., Volland C., Görich S., Koneberg R. Parenteral protein delivery systems using biodegradable polyesters of ABA block structure, containing hydrophobic poly(lactide-coglycolide) A blocks and hydrophilic poly(ethylene oxide) B blocks. J. Control. Release. 39:1996;315-326.
15. Nihant N., Shugens C., Grandfils C., Jérome R., Teyssié P. Polylactide microparticles prepared by double emulsion-evaporation. II effect of the poly(lactide-co-glycolide) composition on the stability of the primary and secondary emulsions. J. Colloid Interface Sci. 173:1995;55-65.
16. Ogawa Y., Yamamoto M., Takada S., Okada H., Shimamoto T. Controlled-release of leuprodile acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer. Chem. Pharm. Bull. 36:1988;1502-1507.
17. Penco M., Marcioni S., Ferruti P., D'antone S., Deghengi R. Degradation behaviour of block copolymers containing poly(lactic-glycolic acid) and poly(ethylene glycol) segments. Biomaterials. 17:1996;1583-1590.
18. Peterson G.L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83:1977;346-356.
19. Ronneberger B., Kao W.J., Anderson J.M., Kissel T. In vivo biocompatiblility studies of ABA triblock copolymers consisting of poly(L-lactic-co-glycolic acid) A. blocks attached to central poly(oxyethylene) B. blocks. J. Biomed. Mater. Res. 30:1996;31-40.
20. Sah H.K., Toddywala R., Chien Y.W. Biodegradable microcapsules prepared by a W/O/W technique: effects of shear force to make a primary W/O emulsion on their morphology and protein release. J. Microencapsul. 12:1995;59-69.
21. Sedmak J.J., Grossberg S.E. A rapid, sensitive and versatile assay for protein using coomassie brilliant blue G250. Anal. Biochem. 79:1977;544-552.
22. Shah S.S., Zhu K.J., Pitt C.G. Poly D.L lactic acid: Polyethylene glycol block copolymers. The influence of polyethylene glycol on the degradation of poly D,L lactic acid. J. Biomater. Sci. Polymer. Ed. 5:1994;421-431.
23. Shugens C., Laruelle N., Nihant N., Grandfils C., Jérome R., Teyssié P. Effect of the emulsion stability on the morphology and porosity of semicrystalline poly L-lactide microparticles prepared by W/O/W double emulsion-evaporation. J. Control. Release. 32:1994;161-176.
24. Soriano I., Delgado A., Diaz R.V., Evora C. Use of surfactants in polylactic acid protein microspheres. Drug Dev. Ind. Pharm. 21:1995;549-558.
25. Tabata Y., Takebayashi Y., Ueda T., Ikada Y. A formulation method using D,L-lactic acid oligomer for protein release with reduced initial burst. J. Control. Release. 23:1993;55-64.
26. Tabata Y., Gupta S., Langer R. Controlled delivery systems for proteins using polyanhydride microspheres. Pharm. Res. 10:1993;487-496.
27. Vert M., Li S., Garreau H. More about the degradation of LA/GA derived matrices in aqueous media. J. Control. Release. 16:1991;15-26.
28. Williams D.L., Nuiwayser E.S., Creeden D.E., Gay M.H. Microencapsulated local anesthetics. Proc. Int. Symp. Control. Rel. Bioact. Mater. 11:1984;69-74.
29. Yan C., Reseau J.H., Hewetson J., West M., Rill W.L., Kende M. Characterization and morphological analysis of protein-loaded poly(lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique. J. Control. Release. 32:1994;231-241.
30. Yolles S., Eldridge J.E., Leafe T.D., Woodland J.H., Blake D.R., Meyer F.J. Long-acting delivery systems for narcotic antagonists II. Release rates of naltrexone from poly(lactic acid) composites. J. Pharm. Sci. 64:1975;348-349.
31. Zambaux M.F., Bonneaux F., Gref R., Maincent P., Dellacherie E., Alonso M.J., Labrude P., Vigneron C. Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method. J. Control. Release. 50:1998;31-40.
32. Zwick M.M. The blue complexes of iodine with poly(vinyl alcohol) and amylose. J. Polym. Sci. 4:1966;1642-1644.