Association of a lymphotoxin α gene polymorphism and atopy in Italian families

Journal of Medical Genetics

Volumn 36, Issue 4, 1999, Pages 323-325

  Trabetti, Elisabetta ^a   Patuzzo, Cristina ^a   Malerba, Giovanni ^a   Galavotti, Roberta ^a   Martinati, Laura Carmen ^a   Boner, Attilio L ^a   Pignatti, Pier Franco ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Asthma; Atopy; LT ; TNF

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN E; LYMPHOTOXIN; TUMOR NECROSIS FACTOR;

AIRWAY; ARTICLE; ASTHMA; ATOPY; BRONCHUS HYPERREACTIVITY; DNA POLYMORPHISM; FAMILY; FEMALE; GENOTYPE; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; PRICK TEST; PRIORITY JOURNAL;

ALLELES; GENOTYPE; HUMANS; ITALY; LYMPHOTOXIN-ALPHA; PHENOTYPE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

BRONCHUS;

EID: 0032950209     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1988;136:225-44.
2. Weiss ST, Tager IB, Weiss JW, Munoza A, Speizer FE, Ingram RM. Airway responsiveness in a population sample of adults and children. Am Rev Respir Dis 1984;129:898-902.
3. Sears MR, Burrows B, Flannery EM. Relation between airways responsiveness and serum IgE in children with asthma and apparently normal children. N Engl J Med 1991;325:1067-71.
4. Duffy DL, Martin NG, Battistutta D. Genetics of asthma and hay fever in Australian twins. Am Rev Respir Dis 1990;142:1351-8.
5. Hopp RJ, Bewtra AK, Biven R, Nair NM, Townley RG. Bronchial reactivity pattern in nonasthmatic parents of asthmatics. Ann Allergy 1988;61:184-6.
6. Sibbald B, Turner-Warwick M. Factors influencing the prevalence of asthma among first degree relatives of extrinsic and intrinsic asthmatics. Thorax 1979;34:332-7.
7. Wilkinson J, Holgate ST. Candidate locus approach to the genetics of asthma and atopy. From genetics to quality of life. The optimal treatment and management of asthma. In: Chanez P, Bousquet J, Michel FB, Godard P, eds. Proceedings of the XVth World Congress of Asthmology, Montpellier, 24-27 April 1996. Paris: Hogrefe & Huber, 1996:1-8.
8. Marsh DG. Genetic studies of IgE responsiveness and asthma. From genetics to quality of life. The optimal treatment and management of asthma. In: Chanez P, Bousquet J, Michel FB, Godard P, eds. Proceedings of the XVth World Congress of asthmology, Montpellier, April 24-27, 1996, Paris: Hogrefe & Huber, 1996:9-14.
9. Anticevich SZ, Hughes JM, Black JL, Armour CL. Induction of human airway hyperresponsiveness by tumour necrosis factor-alpha. Eur J Pharmacol 1995;284:221-5.
10. Shah A, Church MK, Holgate ST. Tumour necrosis factor alpha: a potential mediator of asthma. Clin Exp Allergy 1995;25:1038-44.
11. Messer G, Spengler U, Jung MC, et al. Polymorphic structure of the tumour necrosis factor (TNF) locus: an Ncol polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J Exp Med 1991;173:209-19.
12. Carroll MC, Katzman P, Alicot EM, et al. Linkage map of the human major histocompatibility complex including the tumour necrosis factor genes. Proc Natl Acad Sci USA 1987;84:8535-9.
13. Wilson AG, Symons JA, McDowell TL, Di Giovine FS, Duff GW. Effects of a tumour necrosis factor (TNFα) promoter base transition on transcriptional activity. Br J Rheumatol 1994;33:89A.
14. Moffatt MF, Cookson OCM. Tumour necrosis factor haplotypes and asthma. Hum Mol Genetics 1997;6:551-4.
15. Albuquerque RV, Hayden CM, Palmer LJ, et al. Association of polymorphisms within the tumour necrosis factor (TNF) genes and chilhood asthma. Clin Exp Allergy 1998;28:578-84.
16. Martinati LC, Trabetti E, Casartelli A, Boner AL, Pignatti PF. Affected sib-pair and mutation analyses of the high affinity IgE receptor beta chain locus in Italian families with atopic asthmatic children. Am J Respir Crit Care Med 1996;153:1682-5.
17. Trabetti E, Cusin V, Malerba G, et al. Association of the Fc∈RIb gene with bronchial hyperresponsiveness in an Italian population. J Med Genet 1998;35:680-1.
18. Wilson AG, Di Giovine FS, Blakemore AIF, Duff GW. Single base polymorphism in the human tumour necrosis factor alpha (TNFα) gene detectable by NcoI restriction of PCR product. Hum Mol Genet 1992;1:353.
19. Sham PC, Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet 1995;59:323-36.
20. Blumenthal M, Marcus-Bagley D, Awdeh Z, Johnson B, Yunis EJ, Alper CA. HLA-DR2, [HLA-B7, SC31, DR2], and [HLA-B8, SC01, DR3] haplotypes distinguish subjects with asthma from those with rhinitis only in ragweed pollen allergy. J Immunol 1992;148:411-16.
21. Wilson AG, De Vries N, Pociot F, Di Giovine FS, Van Der Putte LBA, Duff GW. An allelic polymorphism within the human tumour necrosis factor α promoter region is strongly associated with HLA A1, B8, and DR3 alleles. J Exp Med 1993;177:557-60.
22. D'Amato M, Scotto D'Abusco A, Maggi E, et al. Association of responsiveness to the major pollen allergen of Parietaria officinalis with HLA-DRB1* alleles. Hum Immunol 1996;46:100-6.
23. Aron Y, Desmazes-Dufeu N, Matran R, et al. Evidence of a strong, positive association between atopy and the HLA class II alleles DR4 and DR7. Clin Exp Allergy 1996;26:821-8.