Affected sib-pair and mutation analyses of the high affinity IgE receptor beta chain locus in Italian families with atopic asthmatic children

American Journal of Respiratory and Critical Care Medicine

Volumn 153, Issue 5, 1996, Pages 1682-1685

  Martinati, Laura C ^a   Trabetti, Elisabetta ^a   Casartelli, Alessandro ^a   Boner, Attilio L ^a   Pignatti, Pier Franco ^a,b  

^a UNIVERSITY OF VERONA   (Italy)

^b Institute of Biology and Genetics   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN E RECEPTOR; MICROSATELLITE DNA;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ARTICLE; BETA CHAIN; CHILD; FEMALE; GENE AMPLIFICATION; GENE MUTATION; GENETIC LINKAGE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SIBLING;

EID: 0029916075     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.153.5.8630620     Document Type: Article

References (32)

1. Sheffer, A. L. 1991. Guidelines for the management of asthma. NHLBI Expert Panel Report, March 11, 1991. Pediatr. Allergy Immunol. 5: 1-188.
2. Sears, M. R., B. Burrows, and E. M. Flannery. 1991. Relation between airways responsiveness and serum IgE in children with asthma and apparently normal children. N. Engl. J. Med. 325:1067-1071.
3. Kjellman, N. I. M. 1977. Atopic disease in seven-year-old children. Incidence in relation to family history. Acta Paediatr. Scand. 66:465-471.
4. Horwood, L. J., D. M. Fergusson, B. A. Hous, and F. T. Shannon. 1985. Social and familial factors in the development of early childhood asthma. Pediatrics 75:859-868.
5. Hopp, R. J., A. K. Bewtra, G. D. Watt, N. M. Nair, and R. G. Townley. 1984. Genetic analysis of allergic disease in twins. J. Allergy Clin. Immunol. 73:265-270.
6. Sibbald, B. 1980. Extrinsic and intrinsic asthma: influence of classification on family history of asthma and allergic disease. Clin. Allergy 10:313-318.
7. Aberg, N. 1993. Familial occurrence of atopic disease: genetic versus environmental factors. Clin. Exp. Allergy 23:829-834.
8. Hasstedt, S. J., D. G. Meyers, D. G. Marsh, M. Skolnick, M. C. King, W. B. Bias, and D. B. Amos. 1981. The inheritance of immunoglobulin E: genetic model fitting. Am. J. Med. Genet. 14:61-66.
9. Cookson, W. O. C. M., and J. M. Hopkin. 1988. Dominant inheritance of atopic immunoglobulin IgE responsiveness. Lancet i:86-88.
10. Cookson, W. O. C. M., P. A. Sharp, J. A. Faux, and J. M. Hopkin. 1989. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q. Lancet i: 1292-1295.
11. Young, R. P., P. A. Sharp, J. R. Lynch, J. A. Faux, G. M. Lathrop, W. O. C. M. Cookson, and J. M. Hopkin. 1992. Confirmation of genetic linkage between atopic IgE responses and chromosome 11q13. J. Med. Genet. 29:236-238.
12. Cookson, W. O. C. M., R. P. Young, A. J. Sandford, M. F. Moffatt, T. Shirakawa, P. A. Sharp, J. A. Faux, C. Julier, P. N. Le Souef, Y. Nakamura, G. M. Lathrop, and J. M. Hopkin. 1992. Maternal inheritance of atopic IgE responsiveness on chromosome 11q. Lancet 340:381-384.
13. Hizawa, N., E. Yamaguchi, M. Ohe, A. Itoh, K. Furuya, and N. Ohnuma. 1992. Lack of linkage between atopy and locus 11q13. Clin. Exp. Allergy 22:1065-1069.
14. Lympany, P., K. Welsh, G. MacCochrane, D. M. Kemeny, and T. H. Lee. 1991. Genetic analysis using DNA polymorphism of the linkage between chromosome 11q13 and atopy and BHR to methacholine. J. Allergy Clin. Immunol. 87:204.
15. Sandford, A. J., T. Shirakawa, M. F. Moffatt, S. E. Daniels, C. Ra, J. A. Faux, R. P. Young, Y. Nakamura, G. M. Lathrop, W. O. C. M. Cookson, and J. M. Hopkin. 1993. Localisation of atopy and beta subunit of high-affinity IgE receptor on chromosome 11q. Lancet 341:332-334.
16. Maurer, D. 1994. Expression of funcional high affinity immunoglobulin E receptors on monocytes of atopic individuals. J. Exp. Med. 179: 745-750.
17. Shirakawa, T., A. Li, M. Dubowitz, J. W. Dekker, A. E. Shaw, J. A. Faux, C. Ra, W. O. C. M. Cookson, and J. M. Hopkin. 1994. Association between atopy and variants of the beta subunit of the high-affinity immunoglobulin E receptor. Nature Genet. 7:125-130.
18. American Thoracic Society. 1962. Definition and classification of chronic bronchitis, asthma and pulmonary emphysema. Am. Rev. Respir. Dis. 85:762-768.
19. Dreborg, S., and A. Freu. 1993. Position paper: allergen standardization and skin tests. Allergy 48(Suppl. 14):48-82.
20. Bjorksen, B.,and J. Gerrard. 1990. Environmental and developmental factors in allergic disease in infancy and early childhood. In D. Marsh and M. Blumenthal, editors. Genetic and Environmental Factors in Clinical Allergy. University of Minnesota Press, Minneapolis. 84-96.
21. Arshad, S. H., S. Matthews, C. Grant, and D. W. Hide. 1992. Effect of allergen avoidance on development of allergic disorders in infancy. Lancet 339:1493-1497.
22. Cline, M. G., and B. Burrows. 1989. Distribution of allergy in a population sample residing in Tucson, Arizona. Thorax 44:425-431.
23. Moffatt, M. F., P. A. Sharp, J. A. Faux, R. P. Young, W. O. C. M. Cookson, and J. M. Hopkin. 1992. Factors confounding genetic linkage between atopy and chromosome 11q. Clin. Exp. Allergy 22:1046-1051.
24. Blumenthal, M. N., K. K. Namboodiri, G. Gleich, R. C. Elston, and E. Yunis. 1981. Genetic transmission of serum IgE levels. Am. J. Med. Genet. 10:219-228.
25. Meyers, D. A., W. B. Bias, and D. G. Marsh. 1982. A genetic study of total IgE levels in the Amish. Hum. Hered. 32:15-23.
26. Marsh, D. G., W. B. Bias, and K. Ishizaka. 1974. Genetic control of basal serum immunoglobulin E level and its effect on specific reaginic sensitivity. Proc. Natl. Acad. Sci U.S.A. 71:3588-3592.
27. Amelung, P. J., C. I. M. Panhuysen, D. S. Postma, R. C. Levitt, G. H. Koeter, C. A. Francomano, E. R. Bleecker, and D. A. Meyers. 1992. Atopy and bronchial hyperresponsiveness: exclusion of linkage to markers on chromosomes 11q and 6p. Clin. Exp. Allergy 22:1077-1084.
28. Brereton, H. M., R. E. Ruffin, P. J. Thompson, and D. R. Turner. 1994. Familial atopy in Australian pedigrees: adventitious linkage to chromosome 8 is not confirmed nor is there evidence of linkage to the high affinity IgE receptor. Clin. Exp. Allergy 24:868-877.
29. Yanagihara, Y., M. Sarfati, D. Marsh, T. Nutman, and G. Delespesse. 1990. Serum levels of IgE binding factor (soluble D23) in diseases associated with elevated IgE. Clin. Exp. Allergy 20:395-401.
30. Marsh, D. G., J. D. Neely, D. R. Breazeale, B. Ghosh, L. R. Freidhoff, E. Ehrlich-Kautzky, C. Schou, and T. H. Beaty. 1994. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum IgE concentrations. Science 264:1152-1156.
31. Meyers, D. A., D. S. Postma, C. I. M. Panhuysen, J. Xu, P. J. Amelung, R. C. Levitt, and E. R. Bleecker. 1994. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 23: 464-470.
32. Bjorksten, B. 1994. Risk factors in early childhood for the development of atopic diseases. Allergy 49:400-407.