Mouse lymphoma workshop: Victoria, British Columbia, Canada, March 27, 1996 - Protocol issues regarding the use of the microwell method of the mouse lymphoma assay

Environmental and Molecular Mutagenesis

Volumn 29, Issue 4, 1997, Pages 434-438

  Sofuni, Toshio ^a   Wilcox, Philip ^b   Shimada, Hiroyasu ^c   Clements, Julie ^d   Honma, Masamitsu ^a   Clive, Donald ^e   Green, Michael ^f   Thybaud, Veronique ^g   San, Richard H C ^h   Elliott, Barry M ⁱ   Müller, Lutz ^j  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b GLAXOSMITHKLINE   (United Kingdom)

^c DAIICHI SANKYO CO   (Japan)

^d UK   (United Kingdom)

^e University of Sussex ^*

^f UNIVERSITY OF SUSSEX   (United Kingdom)

^g SANOFI   (France)

^h Microbiological Associates Inc   (United States)

ⁱ ASTRAZENECA   (United Kingdom)

^j Fed Inst Drugs and Med Devices   (Germany)

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Author keywords

Consensus; Microwell method; Mouse lymphoma assay; Protocol

Indexed keywords

CAFFEINE; DIETHYLSTILBESTROL; GRISEOFULVIN; MUTAGENIC AGENT; TIABENDAZOLE; VINBLASTINE; VINCRISTINE; ZALCITABINE;

ANIMAL CELL; ASSAY; CELL MUTANT; CONFERENCE PAPER; CYTOTOXICITY; LYMPHOMA; METABOLIC ACTIVATION; METHODOLOGY; MOUSE; NONHUMAN; PRACTICE GUIDELINE;

ANIMALIA; VICTORIA;

EID: 0030742767     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1997)29:4<434::AID-EM13>3.0.CO;2-F     Document Type: Conference Paper

References (5)

1. Clive D, Johnson KO, Spector JFS, Batson AG. Brown MMM (1979): Validation and characterization of the L5178Y/TK+/-mouse lymphoma mutagen assay system. Mutat Res 59:61-108.
2. Clive D, Bolcsfoldi G, Clements J, Cole J, Honma M, Majeska J, Moore M, Müller L, Myhr B, Oberly T, Oudelhkim M-C, Rudd C, Shimada H, Sofuni T, Thybaud V, Wilcox P (1995): Consensus agreement regarding protocol issues discussed during the mouse lymphoma workshop: Portland, Oregon, May 7, 1994. Environ Mol Mutagen 25:165-168.
3. Cole J, Arlett CF, Green MHL, Lowe J, Muriel W (1983): A comparison of the agar cloning and microtitration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells. Mutat Res 111:371-386.
4. Sofuni T, Honma M, Hayashi M, Shimada H, Tanaka N, Wakuri S, Awogi T, Yamamoto KI, Nishi Y, Nakadate M (1996): Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study. Mutagenesis 11:349-355.
5. Robinson WD, Healy MJR, Green MHL, Cole J, Gatehouse D, Garner RC (1989): Statistical evaluation of bacterial/mammalian fluctuation test. In Kirkland DJ (ed.) "Statistical Evaluation of Mutagenicity Test Data." Cambridge: Cambridge University Press, pp 102-140.