Internalization of G protein-coupled receptors in single olfactory receptor neurons

Journal of Neurochemistry

Volumn 72, Issue 2, 1999, Pages 541-548

  Rankin, Michele L ^a   Alvania, Rebecca S ^a   Gleason, Evanna L ^a   Bruch, Richard C ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Clathrin; Dynamin; Fluorescence microscopy; G protein coupled receptors; Olfactory receptor neuron; Receptor internalization

Indexed keywords

4 CARBOXYPHENYLGLYCINE; CAVEOLIN; CLATHRIN; DYNAMIN; FLUORESCENT DYE; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; METABOTROPIC RECEPTOR; OKADAIC ACID;

ANIMAL CELL; ARTICLE; CATFISH; CONTROLLED STUDY; DENDRITE; HELA CELL; HUMAN; HUMAN CELL; INTERNALIZATION; NERVE CELL; NERVE CELL MEMBRANE; NONHUMAN; NUCLEOTIDE SEQUENCE; ODOR; OLFACTORY RECEPTOR; PERIKARYON; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

EID: 0032948915     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0720541.x     Document Type: Article

References (30)

1. Barylko B., Binns D., Lin K. M., Atkinson M. A. L., Jameson D. M., Yin H. L., and Albanesi J. P. (1998) Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides. J. Biol. Chem. 273, 3791-3797.
2. Betz W. J., Mao F., and Bewick G. S. (1992) Activity-dependent fluorescent staining and destaining of living vertebrate motor nerve terminals. J. Neurosci. 12, 363-375.
3. Boekhoff I., Inglese J., Schleicher S., Koch W. J., Lefkowitz R. J., and Breer H. (1994) Olfactory desensitization requires membrane targeting of receptor kinase mediated by βγ-subunits of heterotrimeric G proteins. J. Biol. Chem. 269, 37-40.
4. Bruch R. C. (1996) Phosphoinositide second messengers in olfaction. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 113, 451-459.
5. Bruch R. C. and Abogadie F. C. (1995) Western blotting, in Experimental Cell Biology of Taste and Smell (Spielman A. I. and Brand J. G., eds), pp. 187-192. CRC Press, Boca Raton, Florida.
6. Bruch R. C. and Medler K. F. (1996) A regulator of G-protein signaling in olfactory receptor neurons. Neuroreport 7, 2941-2944.
7. Bruch R. C., Kang J., Moore M. L., and Medler K. F. (1997a) Protein kinase C and receptor kinase gene expression in olfactory receptor neurons. J. Neurobiol. 33, 387-394.
8. Bruch R. C., Medler K. F., Tran H. N., and Hamlin J. A. (1997b) G-protein βγ-subunit genes expressed in olfactory receptor neurons. Chem. Senses 22, 587-592.
9. Conn P. J. and Pin J. P. (1997) Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol. 37, 205-237.
10. Cook T. A., Urrutia R., and McNiven M. A. (1994) Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues. Proc. Natl. Acad. Sci. USA 91, 644-648.
11. Dawson T. M., Arriza J. L., Jaworsky D. E., Borisy F. F., Attramadal H., Lefkowitz R. J., and Ronnett G. V. (1993) β-Adrenergic receptor kinase-2 and β-arrestin-2 as mediators of odorant-induced desensitization. Science 259, 825-829.
12. Ferguson S. S. G., Zhang J., Barak L. S., and Caron M. G. (1997) Pleiotropic role for GRKs and β-arrestins in receptor regulation. News Physiol. Sci. 12, 145-151.
13. Gleason E., Borges S., and Wilson M. (1993) Synaptic transmission between pairs of retinal amacrine cells in culture. J. Neurosci. 13, 2359-2370.
14. Heuser J. E. and Anderson R. G. W. (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J. Cell Biol. 108, 389-400.
15. 2-adrenergic receptor. J. Biol. Chem. 273, 322-328.
16. 2+-sensitive phospholipid-binding protein with very high affinity for protein kinase C. J. Biol. Chem. 269, 21043-21050.
17. Medler K. F., Tran H. N., Parker J. M., Caprio J., and Bruch R. C. (1998) Metabotropic glutamate receptor expression in olfactory receptor neurons from the channel catfish, Ictalurus punctatus. J. Neurobiol. 35, 94-104.
18. Nakata T., Iwamoto A., Noda Y., Takemura R., Yoshikura H., and Hirokawa N. (1991) Predominant and developmentally regulated expression of dynamin in neurons. Neuron 7, 461-469.
19. Ngai J., Dowling M., Buck L., Axel R., and Chess A. (1993) The family of genes encoding odorant receptors in the channel catfish. Cell 72, 657-666.
20. Okamoto T., Schlegel A., Scherer P. E., and Lisante M. P. (1998) Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J. Biol. Chem. 273, 5419-5422.
21. Parton R. G., Joggerst B., and Simons K. (1994) Regulated internalization of caveolae. J. Cell Biol. 127, 1199-1215.
22. Restrepo D. and Teeter J. H. (1990) Olfactory neurons exhibit heterogeneity in depolarization-induced calcium changes. Am. J. Physiol. 258, C1051-C1061.
23. Restrepo D., Miyamoto T., Bryant B. P., and Teeter J. H. (1990) Odor stimuli trigger influx of calcium into olfactory neurons of the channel catfish. Science 249, 1166-1168.
24. Roettger B. F., Rentsch R. U., Pinon D., Holicky E., Hadac E., Larken J. M., and Miller L. J. (1995) Dual pathways of internalization of the cholecystokinin receptor. J. Cell Biol. 128, 1029-1041.
25. Ryan T. A., Reuter H., Wendland B., Schweizer F. E., Tsien R. W., and Smith S. J. (1993) The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron 11, 713-724.
26. Schleicher S., Boekhoff I., Arriza J., Lefkowitz R. J., and Breer H. (1993) A β-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination. Proc. Natl. Acad. Sci. USA 90, 1420-1424.
27. Simonds W. F. (1994) G protein βγ subunits: diversity, structure and functions, in C Proteins (Spiegel A. M., Jones T. L. Z., Simonds W. F., and Weinstein L. S., eds), pp. 75-94. R. G. Landes, Austin.
28. Slowiejko D. M., McEwen E. L., Ernst S. A., and Fisher S. K. (1996) Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed. J. Neurochem. 66, 186-196.
29. Stevens C. F. and Tsujimoto T. (1995) Estimates for the pool size of releasable quanta at a single central synapse and for the time required to refill the pool. Proc. Natl. Acad. Sci. USA 92, 846-849.
30. Sweitzer S. M. and Hinshaw J. E. (1998) Dynamin undergoes a GTP-dependent conformational change causing vesiculation. Cell 93, 1021-1029.