IL-1β and IFN-γ induce the regenerative epidermal phenotype of psoriasis in the transwell skin organ culture system. IFN-γ up-regulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL- 1 production

Journal of Pathology

Volumn 187, Issue 3, 1999, Pages 358-364

  Wei, Liu ^a   Debets, Reno ^c   Hegmans, Joost J ^c   Benner, Robbert ^c   Prens, Errol P ^b  

^a AIR FORCE GENERAL HOSPITAL   (China)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c NONE

Author keywords

Interferon ; Interleukin 1; Keratinocyte; Organ culture; Psoriasis

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1BETA; KERATIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDERMIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; KERATINOCYTE; MALE; ORGAN CULTURE; PHENOTYPE; PRIORITY JOURNAL; PSORIASIS; REGENERATION;

ADULT; AGED; EPIDERMIS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-1; KERATINOCYTES; KERATINS; MALE; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; PSORIASIS; RECOMBINANT PROTEINS; SKIN; TRANSGLUTAMINASES; UP-REGULATION;

EID: 0032948513     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199902)187:3<358::AID-PATH253>3.0.CO;2-8     Document Type: Article

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