Cofactors for human immunodeficiency virus entry into primary macrophages

Journal of Infectious Diseases

Volumn 179, Issue SUPPL. 3, 1999, Pages

  Collman, Ronald G ^a,b   Yi, Yanjie ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN P24; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

CONFERENCE PAPER; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOFLUORESCENCE; MACROPHAGE; MONONUCLEAR CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; VIRUS TRANSMISSION;

FLOW CYTOMETRY; HIV-1; HUMANS; IMMUNITY, NATURAL; MACROPHAGES; POLYMERASE CHAIN REACTION; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR4; RECEPTORS, CYTOKINE; RECEPTORS, HIV;

EID: 0032948504     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314797     Document Type: Conference Paper

References (15)

1. 1. Berger EA. HIV entry and tropism: the chemokine receptor connection. AIDS 1997; 11(suppl A):S3-16.
2. 2. Rucker J, Edinger AL, Sharron M, et al. Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses. J Virol 1997;71:8999-9007.
3. 3. He JL, Chen YZ, Farzan M, et al. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 1997;385:645-9.
4. 4. Doranz BJ, Rucker J, Yi Y, et al. A dual-tropic HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3 and CKR-2b as fusion cofactors. Cell 1996;85:1149-58.
5. 5. Rana S, Besson G, Cook DG, et al. Role of CCR5 in infection of primary macrophages and lymphocytes by M-tropic strains of HIV: resistance to patient-derived and prototype isolates resulting from the Δccr5 mutation. J Virol 1997;71:3219-27.
6. 6. Dean M, Carrington M, Winkler C, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CCR5 structural gene. Science 1996;273:1856-62.
7. 7. Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection of Caucasian individuals bearing mutant alleles of the CCR5 chemokine receptor gene. Nature 1996;382:722-5.
8. 8. Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996 86:367-77.
9. 9. Collman R, Balliet JW, Gregory SA, et al. An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1. J Virol 1992;66:7517-21.
10. 10. Yi Y, Rana S, Turner JD, Gaddis N, Collman RG. CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dualtropic but not T-tropic isolates of human immunodeficiency virus type 1. J Virol 1998;72:772-9.
11. 11. Choe H, Farzan M, Sun Y, et al. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996;85: 1135-48.
12. 12. Endres MJ, Clapham PR, Marsh M, et al. CD-4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell 1996;87:745-56.
13. 13. Combadiere C, Ahuja SK, Murphy PM. Cloning and functional expression of a human eosinophil CC chemokine receptor. J Biol Chem 1995;270: 16491-4.
14. 14. Combadiere C, Ahuja SK, Van Damme J, Tiffany HL, Gao JL, Murphy PM. Monocyte chemoattractant protein-3 is a functional ligand for CC chemokine receptors 1 and 2B. J Biol Chem 1995;270:29671-5.
15. 15. Simmons G, Wilkinson D, Reeves JD, et al. Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry. J Virol 1996;70: 8355-60.