Studies on the histogenesis of myxomatous tissue of human coronary lesions

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 19, Issue 1, 1999, Pages 83-97

  Tjurmin, Alexey V ^a   Ananyeva, Natalya M ^a   Smith, Elizabeth P ^a   Gao, Yamei ^a   Hong, Mun K ^b   Leon, Martin B ^b   Haudenschild, Christian C ^a  

^a HOLLAND LABORATORY   (United States)

^b WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

Angioplasty; Atherosclerosis; Dendritic cells; Pericytes; Smooth muscle cell phenotype

Indexed keywords

CD1 ANTIGEN; CD45 ANTIGEN; CD68 ANTIGEN; MESSENGER RNA; PROTEIN S 100;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; ATHERECTOMY; CORONARY ARTERY ATHEROSCLEROSIS; HUMAN; HUMAN TISSUE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECURRENCE RISK; RESTENOSIS; RISK ASSESSMENT; SMOOTH MUSCLE FIBER; T LYMPHOCYTE; VASCULAR SMOOTH MUSCLE;

EID: 0032947753     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.1.83     Document Type: Article

References (93)

1. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
2. Rosenschein U, Ellis SG, Haudenschild CC, Yakubov SJ, Muller DW, Dick RJ, Topol EJ. Comparison of histopathologic coronary lesions obtained from directional atherectomy in stable angina versus acute coronary syndromes. Am J Cardiol. 1994;73:508-510.
3. Escaned J, de Jong M, Violaris AO, MacLeod DC, Umans VA, van Suylen RJ, de Feyter PJ, Verdouw PD, Serruys PW. Clinical and histological determinants of smooth-muscle cell outgrowth in cultured atherectomy specimens: importance of thrombus organization. Coron Artery Dis. 1993;4:883-890.
4. Miller MJ, Kuntz RE, Friedrich SP, Leidig GA, Fishman RF, Schnitt SJ, Baim DS, Safian RD. Frequency and consequences of intimal hyperplasia in specimens retrieved by directional atherectomy of native primary coronary artery stenoses and subsequent restenoses. Am J Cardiol. 1993; 71:652-658.
5. Waller BF, Johnson DE, Schnitt SJ, Pinkerton CA, Simpson JB, Baim DS. Histologic analysis of directional coronary atherectomy samples: a review of findings and their clinical relevance. Am J Cardiol. 1993;72: 80E-87E.
6. Riessen R, Isner JM, Blessing E, Loushin C, Nikol S, Wight TN. Regional differences in the distribution of the proteoglycans biglycan and decorin in the extracellular matrix of atherosclerotic and restenotic human coronary arteries. Am J Pathol. 1994;144:962-974.
7. Wight TN, Lara S, Riessen R, Le Baron R, Isner J. Selective deposits of versican in the extracellular matrix of restenotic lesions from human peripheral arteries. Am J Pathol. 1997;151:963-973.
8. Garratt KN, Edwards WD, Kaufmann UP, Vlietstra RE, Holmes DR Jr. Differential histopathology of primary atherosclerotic and restenotic lesions in coronary arteries and saphenous vein bypass grafts: analysis of tissue obtained from 73 patients by directional atherectomy. J Am Coll Cardiol. 1991;17:442-448.
9. Schnitt SJ, Safian RD, Kuntz RE, Schmidt DA, Baim DS. Histologic findings in specimens obtained by percutaneous directional coronary atherectomy. Hum Pathol. 1992;23:415-420.
10. Lin H, Kanda T, Hoshino Y, Takase S, Kobayashi I, Nagai R, McManus BM. Versican, biglycan, and decorin protein expression patterns in coronary arteries: analysis of primary and restenotic lesions. Cardiovasc Pathol. 1998;7:31-37.
11. Pickering JG, Weir L, Jekanowski J, Kearney MA, Isner JM. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest. 1993;91: 1469-1480.
12. Strauss BH, Umans VA, van Suylen RJ, de Feyter PJ, Marco J, Robertson GC, Renkin J, Heyndrickx G, Vuzevski VD, Bosman FT. Directional atherectomy for treatment of restenosis within coronary stents: clinical, angiographic and histologic results. J Am Coll Cardiol. 1992;20: 1465-1473.
13. van der Wal AC, Das PK, Tigges AJ, Becker AE. Macrophage differentiation in atherosclerosis: an in situ immunohistochemical analysis in humans. Am J Pathol. 1992;141:161-168.
14. Gown AM, Tsukada T, Ross R. Human atherosclerosis, II: immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. Am J Pathol. 1986;125:191-207.
15. Jonasson L, Holm J, Skalli O, Bondjers G, Hansson GK. Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis. 1986;6:131-138.
16. Hansson GK. Immune and inflammatory mechanisms in the development of atherosclerosis. Br Heart J. 1993;69:S38-S41.
17. Escaned J, van Suylen RJ, MacLeod DC, Umans VA, de Jong M, Bosman FT, de Feyter PJ, Serruys PW. Histologic characteristics of tissue excised during directional coronary atherectomy in stable and unstable angina pectoris. Am J Cardiol. 1993;71:1442-1447.
18. Virmani R. Cardiac myxoma. In: Burke A, Virmani R, eds. Tumors of the Heart and Great Vessels. Washington, DC: Armed Forces Institute of Pathology; 1996:21-46.
19. Bowers WE, Goodell EM. Dendritic cell ontogeny. Res Immunol. 1989; 140:880-883.
20. Zhang J, Yu ZX, Fujita S, Yamaguchi ML, Ferrans VJ. Interstitial dendritic cells of the rat heart: quantitative and ultrastructural changes in experimental myocardial infarction. Circulation. 1993;87:909-920.
21. Teunissen MB. Dynamic nature and function of epidermal Langerhans cells in vivo and in vitro: a review, with emphasis on human Langerhans cells. Histochem J. 1992;24:697-716.
22. Reid CD. The dendritic cell lineage in haemopoiesis. Br J Haematol. 1997;96:217-223.
23. Bobryshev YV, Lord RS, Rainer S, Jamal OS, Munro VF. Vascular dendritic cells and atherosclerosis. Pathol Res Pract. 1996;192:462-467.
24. Wood GS, Turner RR, Shiurba RA, Eng L, Warnke RA. Human dendritic cells and macrophages: in situ immunophenotypic definition of subsets that exhibit specific morphologic and microenvironmental characteristics. Am J Pathol. 1985;119:73-82.
25. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol. 1991;9:271-296.
26. Jaffe R. Review of human dendritic cells: isolation and culture from precursors. Pediatr Pathol. 1993;13:821-837.
27. Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol. 1997;9:10-16.
28. Sprecher E, Becker Y. Role of Langerhans cells and other dendritic cells in disease states. In Vivo. 1993;7:217-227.
29. Scott NA, Cipolla GD, Ross CE, Dunn B, Martin FH, Simonet L, Wilcox JN. Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries. Circulation. 1996;93:2178-2187.
30. Shi Y, O'Brien JE, Fard A, Mannion JD, Wang D, Zalewski A. Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation. 1996;94:1655-1664.
31. Shi Y, O'Brien JE Jr, Mannion JD, Morrison RC, Chung W, Fard A, Zalewski A. Remodeling of autologous saphenous vein grafts: the role of perivascular myofibroblasts. Circulation. 1997;95:2684-2693.
32. Nicosia RF, Villaschi S. Rat aortic smooth muscle cells become pericytes during angiogenesis in vitro. Lab Invest. 1995;73:658-666.
33. Meyrick B, Reid L. Ultrastructural features of the distended pulmonary arteries of the normal rat. Anat Rec. 1979;193:71-97.
34. Shepro D, Morel NM. Pericyte physiology. FASEB J. 1993;7:1031-1038.
35. Hirschi KK, D'Amore PA. Pericytes in the microvasculature. Cardiovasc Res. 1996;32:687-698.
36. Schmidt RA, Wirtala J. A modification of Movat's pentachrome stain with improved reliability of elastin staining. J Histotech. 1996;19: 325-327.
37. Luna LG, ed. Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology. New York, NY: McGraw-Hill Book Co; 1968:81-82.
38. Tjurmin AV, Hong MK, Haudenschild CC, Kent KM, Pichard AD, Leon MB. Histopathologic observations of directional coronary atherectomy (DCA) specimens after excimer laser angioplasty in complex coronary lesions. J Invasive Cardiol. 1996;8:90. Abstract.
39. Langerhans P. Über die nerven der menschlichen havt. Virchows Arch Pathol Anat. 1868;44:325-337.
40. Bagasra O, Seshamma T. In: Hansen J, ed. Protocol: In Situ Amplification and Hybridization. Philadelphia, Pa: Thomas Jefferson University, Omar Bagasra; 1993:1-16.
41. Miller MA, Kolb PE, Raskind MA. A method for simultaneous detection of multiple mRNAs using digoxigenin and radioisotopic cRNA probes. J Histochem Cytochem. 1993;41:1741-1750.
42. Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G. A monoclonal antibody against α-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol. 1986;103:2787-2796.
43. Lees-Miller JP, Heeley DH, Smillie LB, Kay CM. Isolation and characterization of an abundant and novel 22-kDa protein (SM22) from chicken gizzard smooth muscle. J Biol Chem. 1987;262:2988-2993.
44. Weissberg PL, Cary NR, Shanahan CM. Gene expression and vascular smooth muscle cell phenotype. Blood Press Suppl. 1995;2:68-73.
45. Osborn M, Weber K. Intermediate filaments: cell-type-specific markers in differentiation and pathology. Cell. 1982;31:303-306.
46. Rungger-Brandle E, Gabbiani G. The role of cytoskeletal and cytocontractile elements in pathologic processes. Am J Pathol. 1983;110: 361-392.
47. Schmid E, Osborn M, Rungger-Brandle E, Gabbiani G, Weber K, Franke WW. Distribution of vimentin and desmin filaments in smooth muscle tissue of mammalian and avian aorta. Exp Cell Res. 1982;137:329-340.
48. Flugelman MY, Virmani R, Correa R, Yu ZX, Farb A, Leon MB, Elami A, Fu YM, Casscells W, Epstein SE. Smooth muscle cell abundance and fibroblast growth factors in coronary lesions of patients with nonfatal unstable angina: a clue to the mechanism of transformation from the stable to the unstable clinical state. Circulation. 1993;88:2493-2500.
49. Brogi E, Winkles JA, Underwood R, Clinton SK, Alberts GF, Libby P. Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries: association of acidic FGF with plaque microvessels and macrophages. J Clin Invest. 1993;92:2408-2418.
50. Reidy MA. Factors controlling smooth-muscle cell proliferation. Arch Pathol Lab Med. 1992;116:1276-1280.
51. Winkles JA, Alberts GF, Peifley KA, Nomoto K, Liau G, Majesky MW. Postnatal regulation of fibroblast growth factor ligand and receptor gene expression in rat thoracic aorta. Am J Pathol. 1996;149:2119-2131.
52. Speir E, Sasse J, Shrivastav S, Casscells W. Culture-induced increase in acidic and basic fibroblast growth factor activities and their association with the nuclei of vascular endothelial and smooth muscle cells. J Cell Physiol. 1991;147:362-373.
53. Hughes SE, Crossman D, Hall PA. Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteries. Cardiovasc Res. 1993;27:1214-1219.
54. Parums DV, Cordell JL, Micklem K, Heryet AR, Gatter KC, Mason DY. JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J Clin Pathol. 1990;43:752-757.
55. Aruffo A, Seed B. Expression of cDNA clones encoding the thymocyte antigens CD1a, b, c demonstrates a hierarchy of exclusion in fibroblasts. J Immunol. 1989;143:1723-1730.
56. Herman IM, D'Amore PA. Microvascular pericytes contain muscle and nonmuscle actins. J Cell Biol. 1985;101:43-52.
57. Schlingemann RO, Rietveld FJ, de Waal RM, Ferrone S, Ruiter DJ. Expression of the high molecular weight melanoma-associated antigen by pericytes during angiogenesis in tumors and in healing wounds. Am J Pathol. 1990;136:1393-1405.
58. Orekhov AN, Karpova II, Tertov VV, Rudchenko SA, Andreeva ER, Krushinsky AV, Smirnov VN. Cellular composition of atherosclerotic and uninvolved human aortic subendothelial intima: light-microscopic study of dissociated aortic cells. Am J Pathol. 1984;115:17-24.
59. Rekhter MD, Andreeva ER, Mironov AA, Orekhov AN. Three-dimensional cytoarchitecture of normal and atherosclerotic intima of human aorta. Am J Pathol. 1991;138:569-580.
60. Schaefer HE. Proliferation versus atrophy: the ambivalent role of smooth muscle cells in human atherosclerosis. Basic Res Cardiol. 1994;89:47-58.
61. Langhans T. Beiträge zur normalen und pathologischen Anatomie der Arterien. Virchows Arch Pathol Anat. 1866;36:187-226.
62. Schönfelder M. Orthologie und Pathologie der Langhans-Zellen der Aortenintima des Menschen. Pathol Microbiol. 1969;33:129-145.
63. Kocher O, Skalli O, Bloom WS, Gabbiani G. Cytoskeleton of rat aortic smooth muscle cells: normal conditions and experimental intimal thickening. Lab Invest. 1984;50:645-652.
64. Sartore S, Chiavegato A, Franch R, Faggin E, Pauletto P. Myosin gene expression and cell phenotypes in vascular smooth muscle during development, in experimental models, and in vascular disease. Arterioscler Thromb Vasc Biol. 1997;17:1210-1215.
65. Aikawa M, Sakomura Y, Ueda M, Kimura K, Manabe I, Ishiwata S, Komiyama N, Yamaguchi H, Yazaki Y, Nagar R. Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression. Circulation. 1997;96:82-90.
66. Thyberg J, Hedin U, Sjolund M, Palmberg L, Bottger BA. Regulation of differentiated properties and proliferation of arterial smooth muscle cells. Arteriosclerosis. 1990;10:966-990.
67. Chamley-Campbell J, Campbell GR, Ross R. The smooth muscle cell in culture. Physiol Rev. 1979;59:1-61.
68. Winkles JA, Friesel R, Burgess WH, Howk R, Mehlman T, Weinstein R, Maciag T. Human vascular smooth muscle cells both express and respond to heparin-binding growth factor I (endothelial cell growth factor). Proc Natl Acad Sci U S A. 1987;84:7124-7128.
69. Bobryshev YV, Lord RS. Ultrastructural recognition of cells with dendritic cell morphology in human aortic intima: contacting interactions of vascular dendritic cells in athero-resistant and athero-prone areas of the normal aorta. Arch Histol Cytol. 1995;58:307-322.
70. Bobryshev YV, Lord RS. Langhans cells of human arterial intima: uniform by stellate appearance but different by nature. Tissue Cell. 1996;28:177-194.
71. Bobryshev YV, Lord RS. Structural heterogeneity and contacting interactions of vascular dendritic cells in early atherosclerotic lesions of the human aorta. J Submicrosc Cytol Pathol. 1996;28:49-60.
72. Kahn HJ, Marks A, Thom H, Baumal R. Role of antibody to S100 protein in diagnostic pathology. Am J Clin Pathol. 1983;79:341-347.
73. Stemme S, Fager G, Hansson GK. MHC class II antigen expression in human vascular smooth muscle cells is induced by interferon-γ and modulated by tumour necrosis factor and lymphotoxin. Immunology. 1990;69:243-249.
74. Pober JS, Collins T, Gimbrone MA Jr, Cotran RS, Gitlin JD, Fiers W, Clayberger C, Krensky AM, Burakoff SJ, Reiss CS. Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon. Nature. 1983;305:726-729.
75. Wilson BS, Indiveri F, Pellegrino MA, Ferrone S. DR (Ia-like) antigens on human melanoma cells: serological detection and immunochemical characterization. J Exp Med. 1979;149:658-668.
76. McMichael AJ, Pilch JR, Galfre G, Mason DY, Fabre JW, Milstein C. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur J Immunol. 1979;9:205-210.
77. Bradstock KF, Janossy G, Pizzolo G, Hoffbrand AV, McMichael A, Pilch JR, Milstein C, Beverley P, Bollum FJ. Subpopulations of normal and leukemic human thymocytes: an analysis with the use of monoclonal antibodies. J Natl Cancer Inst. 1980;65:33-42.
78. Fithian E, Kung P, Goldstein G, Rubenfeld M, Fenoglio C, Edelson R. Reactivity of Langerhans cells with hybridoma antibody. Proc Natl Acad Sci U S A. 1981;78:2541-2544.
79. Thomas R, Lipsky PE. Dendritic cells: origin and differentiation. Stem Cells. 1996;14:196-206.
80. Hansson GK, Jonasson L, Holm J, Claesson-Welsh L. Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant γ-chain. Clin Exp Immunol. 1986;64:261-268.
81. Jonasson L, Holm J, Skalli O, Gabbiani G, Hansson GK. Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis. J Clin Invest. 1985;76:125-131.
82. Bobryshev YV, Lord RS, Rainer SP, Munro VF. VCAM-1 expression and network of VCAM-1 positive vascular dendritic cells in advanced atherosclerotic lesions of carotid arteries and aortas. Acta Histochem. 1996;98:185-194.
83. Bobryshev YV, Lord RS. S-100 positive cells in human arterial intima and in atherosclerotic lesions. Cardiovasc Res. 1995;29:689-696.
84. Verbeek MM, Otte-Holler I, Wesseling P, Ruiter DJ, de Waal RM. Induction of α-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-β1. Am J Pathol. 1994;144: 372-382.
85. Nehls V, Drenckhahn D. Heterogeneity of microvascular pericytes for smooth muscle type α-actin. J Cell Biol. 1991;113:147-154.
86. Balabanov R, Washington R, Wagnerova J, Dore-Duffy P. CNS microvascular pericytes express macrophage-like function, cell surface integrin αM, and macrophage marker ED-2. Microvasc Res. 1996;52:127-142.
87. Blomhoff R, Wake K. Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB J. 1991;5:271-277.
88. Palacios R. Mechanism of T cell activation: role and functional relationship of HLA-DR antigens and interleukins. Immunol Rev. 1982;63: 73-110.
89. Savage CO, Hughes CC, McIntyre BW, Picard JK, Pober JS. Human CD4+ T cells proliferate to HLA-DR+ allogeneic vascular endothelium: identification of accessory interactions. Transplantation. 1993;56: 128-134.
90. Hirschberg H, Bergh OJ, Thorsby E. Antigen-presenting properties of human vascular endothelial cells. J Exp Med. 1980;152:249s-255s.
91. Suttles J, Miller RW, Moyer CF. T cell-vascular smooth muscle cell interactions: antigen-specific activation and cell cycle blockade of T helper clones by cloned vascular smooth muscle cells. Exp Cell Res. 1995;218:331-338.
92. Parham P. Antigen presentation: chewing the fat. Nature. 1994;372: 615-616.
93. Stemme S, Holm J, Hansson GK. T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45RO and the integrin VLA-1. Arterioscler Thromb. 1992;12:206-211.