Profile of antiepileptic pharmacotherapy in a tertiary referral center in South India: A pharmacoepidemiologic and pharmacoeconomic study

Epilepsia

Volumn 40, Issue 2, 1999, Pages 179-185

  Radhakrishnan, K ^a   Nayak, S Dinesh ^a   Kumar, S Pradeep ^a   Sarma, P Sankara ^a  

^a SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Antiepileptic drugs; Epilepsy syndromes; Pharmacoeconomics; Pharmacoepidemiology; Pharmacotherapy

Indexed keywords

CARBAMAZEPINE; PHENOBARBITAL; PHENYTOIN; VALPROIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; COST BENEFIT ANALYSIS; DRUG COST; DRUG EFFICACY; DRUG TOLERABILITY; EPILEPSY; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; INDIA; INFANT; MAJOR CLINICAL STUDY; MALE; PATIENT REFERRAL; PHARMACOECONOMICS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; COMPREHENSIVE HEALTH CARE; DEVELOPING COUNTRIES; DRUG COSTS; DRUG UTILIZATION; ECONOMICS, PHARMACEUTICAL; EPILEPSY; FEMALE; HEALTH CARE COSTS; HEALTH FACILITIES; HUMANS; INDIA; INFANT; MALE; MIDDLE AGED; PHARMACOEPIDEMIOLOGY;

EID: 0032946961     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1999.tb02072.x     Document Type: Article

References (35)

1. The III and IV Commission on Antiepileptic Drugs of the International League Against Epilepsy. Availability and distribution of antiepileptic drugs in developing countries. Epilepsia 1985;26: 117-21.
2. Mattson RH, Cramer JA, Collins JF, et al. Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985; 313:145-51.
3. Heller AJ, Chesterman P, Elwes RDC, et al. Phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed adult epilepsy: a randomized comparative monotherapy trial. J. Neurol Neurosurg Psychiatry 1995;58:44-50.
4. de Silva M, MacArdle B, McGowan M. et al. Randomized comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy. Lancet 1996;347:709-13.
5. Beghi E, Perucca E. The management of epilepsy in the 1990s: acquisitions, uncertainties and priorities for future research. Drugs 1995;49:680-94.
6. Marson AG, Kadir ZA, Chadwick DW. New antiepileptic drugs: a systematic review of their efficacy and tolerability. BMJ 1996;313: 1169-74.
7. Engel J Jr. Surgery for seizures. N Engl J Med 1996;334:647-52.
8. Reynolds EH, Shorvon SD. Monotherapy or polytherapy for epilepsy? Epilepsia 1981;22:1-10.
9. Pellock JM. Standard approach to antiepileptic drug treatment in the United States. Epilepsia 1994;35(suppl 4):S11-18.
10. Chadwick D. Standard approach to antiepileptic drug treatment in the United Kingdom. Epilepsia 1994;35(suppl 4):S3-10.
11. Schmidt D, Gram L. Monotherapy versus polytherapy in epilepsy: a reappraisal. CNS Drugs 1995;3:194-208.
12. World Development Report. New York: Oxford University Press, 1993:216-9.
13. Pedley T, Kale R. Epilepsy information for the developing world. Epilepsia Digest 1996;1:1.
14. Kannan KP, Thankappan KR, Ramankutty V, Aravindan KP. Health and development in rural Kerala. Trivandrum, India: Kerala Sastra Sahitya Parishad, 1991.
15. Radhakrishnan K, Nayak SD, Santoshkumar B, Rao BM, Thomas SV. Cost-effective epilepsy surgery in a developing country. Inaugural Congress of Asian and Oceanian Epilepsy Organization, Seoul, Korea, 1996. Conference Abstracts 1996;33.
16. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989:30:389-99.
17. World Health Organization (WHO) Collaborating Centre for Drugs Statistics Methodology and Nordic Council on Medicines. Guidelines for DDD. Oslo: World Health Organization/NCM, 1991.
18. de Bittencourt PRM, Adamobkum B, Bharucha N, et al. ILAE Commission Report. Epilepsy in the tropics: II. Clinical presentations, pathophysiology, immunologic diagnosis, economics, and therapy. Epilepsia 1996;37:1128-37.
19. World Development Report. New York: Oxford University Press. 1994:162.
20. Loiseau P, Duche B, Loiseau J. Classification of epilepsies and epileptic syndromes in two different samples of patients. Epilepsia 1991;32:303-9.
21. Osservatorio Regionale per L'Epilessia (OREp). Lombardy. ILAE classification of epilepsies: its applicability and practical value of different diagnostic categories. Epilepsia 1996;37:1051-9.
22. Wijsman DJP, Lammers MW, Hekster YA, et al. Epilepsy treatment in the Netherlands: comparison of two medical centres. Acta Neurol Scand 1993;87:438-42.
23. Medical Research Council Antiepileptic Drug Withdrawal Study Group. Randomized study of antiepileptic drug withdrawal in patients in remission. Lancet 1991;337:1175-80.
24. Lammers MW, Hekster YA, Keyser A, Meinardi H, Renier WO, Herings RMC. Use of antiepileptic drugs in a community-dwelling Dutch population. Neurology 1996;46:62-7.
25. Genton P, Remy C, Vespignani H. Monotherapie et polytherapie lovs de la mise en route d'un traitement antiepileptique: enquete prospective multicentrique de la ligue francaise contre l'epilepsie, avec suivi a 6 mois et a 1 an. Epilepsies 1992;4:75-81.
26. Mirza WU, Credeur LJ, Penry JK. Results of antiepileptic drug reduction in patients with multiple handicaps and epilepsy. Drugs Invest 1993;5:320-6.
27. Mattson RH, Cramer JA, Collins JF, A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic clonic seizures in adults: The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group. N Engl J Med 1992;327:765-71.
28. Collaborative Group for Epidemiology of Epilepsy. Adverse reactions to antiepileptic drugs: a follow up study of 355 patients with chronic antiepileptic drug treatment. Epilepsia 1988;29:787-93.
29. Gastaut H, Osontokun BO. Proposals on antiepileptic pharmacotherapy for use in developing countries. Epilepsia 1976;17:355-60.
30. World Health Organization. Initiative of support to people with epilepsy, Geneva: World Health Organization, 1990.
31. Pal DK, Das T, Chaudhury G, Johnson AL. Neville BGR. Randomised controlled trial to assess acceptability of phenobarbital for childhood epilepsy in rural India. Lancet 1998;351:19-23.
32. Theodore WH, Schulman EA, Porter RJ. Intractable seizures: long-term follow-up after prolonged inpatient treatment in an epilepsy unit. Epilepsia 1983;24:336-43.
33. Collaborative Group for Epidemiology of Epilepsy. Adverse reactions to antiepileptic drugs: a multicenter survey of clinical practice. Epilepsia 1986;27:323-30.
34. Lammers MW, Hekster YA, Keyser A, Meinardi H, Renier WO, van Lier H. Monotherapy or polytherapy for epilepsy revisited: a quantitative assessment. Epilepsia 1995;36:440-6.
35. Mitchell AS. Economic evaluation of anti-epileptic drugs. In: Pachlatko CH, Beran RG, eds. Economic evaluation of epilepsy management. London: John Libbey, 1996:47-58.