A naturalistic comparison of adverse effects between slow titration and loading of divalproex sodium in psychiatric inpatients

Journal of Affective Disorders

Volumn 52, Issue 1-3, 1999, Pages 261-267

  Lima, Wilhelmina J ^a   Dopheide, Julie A ^a   Kramer, Barry A ^b   Earhart, Catherine A ^a   Wincor, Michael Z ^a,b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Adverse effects; Divalproex sodium; Loading; Psychiatric; Titration

Indexed keywords

VALPROATE SEMISODIUM;

ADULT; ANOREXIA; ARTICLE; ASTHENIA; BLEEDING; CHILL; CLINICAL ARTICLE; CLINICAL TRIAL; DISEASE SEVERITY; DOSE RESPONSE; DROWSINESS; DRUG BLOOD LEVEL; DRUG HYPERSENSITIVITY; FACE EDEMA; GASTROINTESTINAL SYMPTOM; HAIR LOSS; HEADACHE; HUMAN; INCIDENCE; MALE; MANIA; PRIORITY JOURNAL; RASH; SINGLE BLIND PROCEDURE; VERTIGO;

ADULT; ANTIMANIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MENTAL DISORDERS; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; VALPROIC ACID;

EID: 0032946299     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(98)00065-2     Document Type: Article

References (21)

1. Allen C.K., Allen R.E. Cognitive disabilities: measuring the social consequences of mental disorders. J. Clin. Psychiatry. 48:1987;185-190.
2. Allen, C.K., Blue, T., Earhart, C., 1995. Understanding Cognitive Performance Modes. Allen Conferences, Florida.
3. Allen, C.K., Earhart, C.A., Blue, T., 1992. Occupational Therapy Treatment Goals for the Physically and Cognitively Disabled. The American Occupational Therapy Association, Maryland.
4. Bowden C.L., Brugger A.M., Swann A.C.et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. J. Am. Med. Assoc. 271:1994;918-924.
5. Baldessarini R.J., Cohen B.M., Teicher M.H. Significance of neuroleptic dose and plasma level in the pharmacological treatment of psychosis. Arch. Gen. Psychiatry. 45:1988;79-91.
6. Bowden C.L., Janicak P.G., Orsulak P.et al. Relation of serum valproate concentration to response in mania. Am. J. Psychiatry. 153:1996;765-770.
7. Delito J.A. The effect of valproate on bipolar spectrum temperamental disorders. J. Clin. Psychiatry. 54:1993;300-304.
8. Freeman T.W., Clothier J.L., Pazzaglia P.et al. A double-blind comparison of valproate and lithium in the treatment of acute mania. Am. J. Psychiatry. 149:1992;108-111.
9. Goodwin, F.K., Jamison, K.R., 1990. Manic-Depressive Illness. Oxford University Press, New York.
10. Guay D.R. The emerging role of valproate in bipolar disorder and other psychiatric disorders. Pharmacotherapy. 15:1995;631-647.
11. Keck P.E. Jr., McElroy S.L., Tugrul K.C.et al. Valproate oral loading in the treatment of acute mania. J. Clin. Psychiatry. 54:1993;305-308.
12. Lott A.D., McElroy S.L., Keys M.A. Valproate in the treatment of behavioral agitation in elderly patients with dementia. J. Neuropsychiatry Clin. Neurosci. 7:1995;314-319.
13. Mazure C.M., Druss B.G., Cellar J.S. Valproate treatment of older psychotic patients with organic mental syndromes and behavioral dyscontrol. J. Am. Geriatr. Soc. 40:1992;914-916.
14. McElroy S.L., Keck P.E., Pope H.G. Sodium valproate: its use in primary psychiatric disorders. J. Clin. Psychopharmacol. 7:1987;16-24.
15. McElroy S.L., Keck P.E. Jr., Pope H.G. Jr.et al. Valproate in psychiatric disorder: literature review and clinical guidelines. J. Clin. Psychiatry. 50(suppl):1989;23-29.
16. McElroy S.L., Keck P.E. Jr., Stanton S.P.et al. A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania. J. Clin. Psychiatry. 57:1996;142-146.
17. McElroy S.L., Keck P.E. Jr., Tugrul K.C.et al. Valproate as a loading treatment in acute mania. Neuropsychobiology. 27:1993;146-149.
18. Pope H.G. Jr., McElroy S.L., Keck P.E. Jr.et al. Valproate in the treatment of acute mania. Arch. Gen. Psychiatry. 48:1991;62-68.
19. Wilder B.J., Karas B.J., Penry J.K.et al. Gastrointestinal tolerance of divalproex sodium. Neurology. 33:1983;808-811.
20. Yassa R., Ghadirian A.M., Schwartz G. Prevalence of tardive dyskinesia in affective disorder patients. J. Clin. Psychiatry. 44:1983;410-412.
21. Young R.C., Biggs J.T., Ziegler V.E.et al. A rating scale for mania: reliability, validity and sensitivity. Br. J. Psychiatry. 133:1978;429-435.