Antibody-dependent cell-mediated cytotoxicity can protect PBMC from infection by cell-associated HIV-1

Clinical Immunology

Volumn 90, Issue 2, 1999, Pages 203-212

  Hildreth, James E K ^a   Hampton, Richard ^a   Halsey, Neal A ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

ADCC; AIDS; Antibody; HIV; Virus neutralization

Indexed keywords

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; LYMPHOCYTE ACTIVATION; MONONUCLEAR CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0032946219     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.1998.4624     Document Type: Article

References (47)

1. Weiss, R. A., How does HIV cause AIDS. Science 260, 1273-1279, 1993.
2. Rosenberg, Z. F., and Fauci, A. S., The immunopathogenesis of HIV infection. Adv. Immunol. 47, 377-431, 1989.
3. Shearer, G. M., and Clerici, M., Protective immunity against HIV infection: has nature done the experiment for us?. Immunol. Today 17, 21-24, 1996.
4. Haynes, B. F., Pantaleo, G., and Fauci, A. S., Toward an understanding of the correlates of protective immunity to HIV infection. Science 271, 324-328, 1996.
5. Westby, M., Manca, F., and Dalgleish, A., The role of the host immune response in determining the outcome of HIV infection. Immunol. Today 17, 120-126, 1996.
6. Koup, R. A., Pikora, C. A., Mazzara, G., Panicali, D., and Sullivan, J. L., Broadly reactive antibody-dependent cellular cytotoxic response to HIV-1 envelope glycoproteins precedes broad neutralizing response in human infection. Viral Immunol. 4, 215-223, 1991.
7. Ahmad, A., and Menezes, J., Antibody-dependent cellular cytotoxicity in HIV infections. FASEB. J. 10, 258-266, 1996.
8. Tyler, D. S., Stanley, S. D., Zolla-Pazner, S., et al., Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies. J. Immunol. 145, 3276-3282, 1990.
9. Norley, S. G., Mikschy, U., Werner, A., Staszewski, S., Helm, E. B., and Kurth, R., Demonstration of cross-reactive antibodies able to elicit lysis of both HIV-1- and HIV-2-infected cells. J. Immunol. 145, 1700-1705, 1990.
10. Tyler, D. S., Lyerly, H. K., and Weinhold, K. J., Anti-HIV-1 ADCC. AIDS Res. Hum. Retroviruses 5, 557-563, 1989.
11. Mabondzo, A., Rouvier, P., Raoul, H., et al., Relationships between humoral factors in HIV-1-infected mothers and the occurrence of HIV infection in their infants. Clin. Exp. Immunol. 102, 476-480, 1995.
12. Ahmad, A., and Menezes, J., Positive correlation between the natural killer and gp120/41-specific antibody-dependent cellular cytotoxic effector functions in HIV-infected individuals. J. Acquired Immune Defic. Syndr. 10, 115-119, 1995.
13. Jenkins, M., Landers, D., Williams-Herman, D., et al., Association between anti-human immunodeficiency virus type 1 (HIV-1) antibody-dependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1. J. Infect. Dis. 170, 308-312, 1994.
14. Dalgleish, A., Sinclair, A., Steel, M., Beatson, D., Ludlam, C., and Habeshaw, J., Failure of ADCC to predict HIV-associated disease progression or outcome in a haemophiliac cohort. Clin. Exp. Immunol. 81, 5-10, 1990.
15. Ljunggren, K., Moschese, V., Broliden, P. A., et al., Antibodies mediating cellular cytotoxicity and neutralization correlate with a better clinical stage in children born to human immunodeficiency virus-infected mothers. J. Infect. Dis. 161, 198-202, 1990.
16. Brenner, B. G., Gryllis, C., and Wainberg, M. A., Role of antibody-dependent cellular cytotoxicity and lymphokine-activated killer cells in AIDS and related diseases. J. Leukocyte Biol. 50, 628-640, 1991.
17. Zack, J. A., Arrigo, S. J., Weitsman, S. R., Go, A. S., Haislip, A., and Chen, I. S. Y., HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure. Cell 61, 213-222, 1990.
18. Lyerly, H. K., Reed, D. L., Matthews, T. J., et al., Anti-GP 120 antibodies from HIV seropositive individuals mediate broadly reactive anti-HIV ADCC. AIDS Res. Hum. Retroviruses 3, 409-422, 1987.
19. Hildreth, J. E. K., and Hyman, J. A., Production and characterization of monoclonal anti-CD 18 anti-idiotype antibodies. Mol. Immunol. 26, 1155-1167, 1989.
20. Greenberg, A. H., and Lydyard, P. M., Observations of IgG1 anti-DNP hybridoma-mediated ADCC and the failure of three IgM anti-DNP hybridomas to mediate ADCC. J. Immunol. 123, 861-869, 1979.
21. Orentas, R. J., and Hildreth, J. E. K., Association of host cell surface adhesion receptors and other membrane proteins with HIV and SIV. AIDS Res. Hum. Retroviruses 9, 1157-1165, 1993.
22. Guo, M. M. L., and Hildreth, J. E. K., HIV-induced loss of CD44 expression in monocytic cell lines. J. Immunol. 151, 2225-2236, 1993.
23. Gomez, M. B., and Hildreth, J. E. K., Antibody to adhesion molecule LFA-1 enhances plasma neutralization of human immunodeficiency virus type 1. J. Virol. 69, 4628-4632, 1995.
24. Nara, P. L., Hatch, W. C., Dunlop, N. M., et al., Simple, rapid, quantitative, syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody. AIDS Res. Hum. Retroviruses 3, 283-302, 1987.
25. Hildreth, J. E. K., Subramanium, A., and Hampton, R. A., HTLV-I-induced syncytium formation mediated by vascular cell adhesion molecule-1 (VCAM-1): Evidence for involvement of cell adhesion molecules in HTLV-I biology. J. Virol. 71, 1173-1180, 1997.
26. Arthur, L. O., Bess, J. W., Sowder, R. C., et al., Cellular proteins bound to immunodeficiency viruses: Implications for pathogenesis and vaccines. Science 258, 1935-1938, 1992.
27. Gelderblom, H. R., Ozel, M., Hausmann, E. H. S., Winkel, T., Pauli, G., and Koch, M. A., Fine structure of human immunodeficiency virus (HIV), immunolocalization of structural proteins and virus-cell relation. Micron Microsc. 19, 41-60, 1988.
28. Evans, L. A., McHugh, T. M., Stites, D. P., and Levy, J. A., Differential ability of human immunodeficiency virus isolates to productively infect human cells. J. Immunol. 138, 3415-3418, 1987.
29. Hober, D., Jewett, A., and Bonavida, B., Lysis of uninfected HIV-1 gp120-coated peripheral blood-derived T lymphocytes by monocyte-mediated antibody-dependent cellular cytotoxicity. FEMS. Immunol. Med. Microbiol. 10, 83-91, 1995.
30. Evans, L. A., Thomson-Honnebier, G., Steimer, K., et al., Antibody-dependent cellular cytotoxicity is directed against both the gp120 and gp41 envelope proteins of HIV. AIDS 3, 273-276, 1989.
31. Rook, A. H., Lane, H. C., Folks, T., McCoy, S., Alter, H., and Fauci, A. S., Sera from HTLV-III/LAV antibody-positive individuals mediate antibody-dependent cellular cytotoxicity against HTLV-III/LAV-infected T cells. J. Immunol. 138, 1064-1067, 1987.
32. Ahmad, A., Morisset, R., Thomas, R., and Menezes, J., Evidence for a defect of antibody-dependent cellular cytotoxic (ADCC) effector function and anti-HIV gp120/41-specific ADCC-mediating antibody titres in HIV-infected individuals. J. Acquired Immune Defic. Syndr. 7, 428-437, 1994.
33. Ljunggren, K., Bottiger, B., Biberfeld, G., Karlson, A., Fenyo, E. M., and Jondal, M., Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus: Presence at different clinical stages. J. Immunol. 139, 2263-2267, 1987.
34. Broliden, K., Sievers, E., Tovo, P. A., et al., Antibody-dependent cellular cytotoxicity and neutralizing activity in sera of HIV-1-infected mothers and their children. Clin. Exp. Immunol. 93, 56-64, 1993.
35. Sawyer, L. A., Katzenstein, D. A., Hendry, R. M., et al., Possible beneficial effects of neutralizing antibodies and antibody-dependent, cell-mediated cytotoxicity in human immunodeficiency virus infection. AIDS Res. Hum. Retroviruses 6, 341-356, 1990.
36. Ojo-Amaize, E., Nishanian, P. G., Heitjan, D. F., et al., Serum and effector-cell antibody-dependent cellular cytotoxicity (ADCC) activity remains high during human immunodeficiency virus (HIV) disease progression. J. Clin. Immunol. 9, 454-461, 1989.
37. Shepp, D. H., Chakrabarti, S., Moss, B., and Quinnan, G. V., Jr., Antibody-dependent cellular cytotoxicity specific for the envelope antigens of human immunodeficiency virus. J. Infect. Dis. 157, 1260-1264, 1988.
38. Baum, L. L., Cassutt, K. J., Knigge, K., et al., HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression. J. Immunol. 157, 2168-2173, 1996.
39. Kohl, S., and Loo, L. S., Protection of neonatal mice against herpes simplex virus infection: Probable in vivo antibody-dependent cell-mediated cytotoxicity. J. Immunol. 129, 370-376, 1982.
40. Rager-Zisman, B., and Allison, A. C., Mechanism of immunologic resistance to herpes simplex virus 1 (HSV-1) infection. J. Immunol. 116, 35-40, 1976.
41. Hayashida, I., Nagafuchi, S., Hayashi, Y., et al., Mechanism of antibody-mediated protection against herpes simplex virus infection in athymic nude mice: Requirement of Fc portion of antibody. Microbiol. Immunol. 26, 497-509, 1982.
42. McKendall, R. R., IgG-mediated viral clearance in experimental infection with herpes simplex virus type 1: Role for neutralization and Fc-dependent functions but not C′ cytolysis and C5 chemotaxis. J. Infect. Dis. 151, 464-470, 1985.
43. Oakes, J. E., and Lausch, R. N., Role of Fc fragments in antibody-mediated recovery from ocular and subcutaneous herpes simplex virus infections. Infect. Immun. 33, 109-114, 1981.
44. Kohl, S., Role of antibody-dependent cellular cytotoxicity in defense against herpes simplex virus infection. Rev. Infect. Dis. 13, 108-114, 1991.
45. Collins, J. J., Sackie, D. M., and Johnson, C. R., Immunotherapy of murine leukemia. IX. The requirement for the Fc portion of antibody for successful passive therapy of Friend leukemia virus-induced disease. Virology 126, 259-266, 1983.
46. Pearson, G. R., Johansson, B., and Klein, G., Antibody-dependent cellular cytotoxicity against Epstein-Barr virus-associated antigens in African patients with nasopharyngeal carcinoma. Int. J. Cancer 22, 120-125, 1978.
47. Pearson, G. R., Qualtiere, L. F., Klein, G., Norin, T., and Bal, I. S., Epstein-Barr virus-specific antibody-dependent cellular cytotoxicity in patients with Burkitt's lymphoma. Int. J. Cancer 24, 402-406, 1979.