Analysis of internal deletions within the BCL6 gene in B-cell non- Hodgkin's lymphoma

British Journal of Haematology

Volumn 105, Issue 1, 1999, Pages 274-277

  Nakamura, Yuichi ^a   Saito, Kenji ^a   Furusawa, Shinpei ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

B NHL; BCL6 gene; Deletion

Indexed keywords

ZINC FINGER PROTEIN;

ARTICLE; B CELL LYMPHOMA; CASE REPORT; CELL LINE; CHROMOSOME 3Q; CHROMOSOME TRANSLOCATION 3; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; GENE DELETION; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; INTRON; NONHODGKIN LYMPHOMA; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 0032944805     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1999.01288.x     Document Type: Article

References (11)

1. Andrews, N.C. & Faller, D.V. (1991) A rapid minipreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Research, 19, 2499.
2. Bernardin, F., Collyn-d'Hooghe, M., Quief, S., Bastard, C., Leprince, D. & Kerckaert, J-P. (1997) Small deletions occur in highly conserved regions of the LAZ3/BCL6 major translocation cluster in one case of non-Hodgkin's lymphoma without 3q27 translocation. Oncogene, 14, 849-855.
3. Dalla-Favera, R. & Cattoretti, G. (1997) Pathogenesis of intermediategrade B-cell lymphomas. The Non-Hodgkin's Lymphomas, 2nd edn (ed. by I. T. Magrath), pp. 377-384. Arnold, London.
4. Denny, P., Swift, S., Connor, F. & Ashworth, A. (1992) An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein. EMBO Journal, 11, 3705-3712.
5. Frumkin, A., Rangini, Z., Ben-Yehuda, A., Gruenbaum, Y. & Fainsod, A. (1991) A chicken caudal homologue. CHox-cad, is expressed in the epiblast with posterior localization and in the early endodermal lineage. Development, 112, 207-219.
6. Mitchell, P.J. & Tijan, R. (1989) Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science, 245, 371-378.
7. Monica, K., Galili, N., Nourse, J., Saltman, D. & Cleary, M.L. (1991) PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Molecular and Cellular Biology, 11, 6149-6157.
8. Nakamura, Y., Miki, T., Miura, I., Hashimoto, K., Miura, A., Akimoto, K., Hirosawa, S., Saito, K., Enokihara, H., Furusawa, S. & Shishido, H. (1996.) Internal DNA deletion within the BCL-6 gene on untranslocated chromosome in non-Hodgkin's lymphoma with 3q27 abnormality. Leukemia, 10, 658-661.
9. Sinclair, A.H., Berta, P., Palmer, M.S., Hawkins, J.R., Griffiths. B.L., Smith, M.J., Foster, J.W., Frisehuuf, A-M., Lovell-Badge. R. & Goodfellow, P.N. (1990) A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature, 346, 240-244.
10. Wingender, E. (1994) Recognition of regulatory regions in genomic sequences. Journal of Biotechnology, 35, 275-280.
11. Ye, B.H., Chaganti, S., Chang, C-C., Niu, H., Corradini, P., Chaganti, R.S.K. & Dalla-Favera, R. (1995) Chromosomal translocations cause deregulated BCL6 expression by promotor substitution in B cell lymphoma. EMBO Journal, 14, 6209-6217.