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Volumn 276, Issue 1 39-1, 1999, Pages

Mechanism of inhibition of VIP-induced LES relaxation by heme oxygenase inhibitor zinc protoporphyrin IX

Author keywords

G protein coupled; Inhibitory neurotransmission; Lower esophageal sphincter; Nitric oxide synthase; Vasoactive intestinal polypeptide

Indexed keywords

ADENYLATE CYCLASE; CHOLERA TOXIN; DEUTEROPORPHYRIN IX; HEME OXYGENASE INHIBITOR; MEMBRANE RECEPTOR; PROTOPORPHYRIN ZINC; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

EID: 0032944426     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.1.g138     Document Type: Article
Times cited : (7)

References (42)
  • 1
    • 0026072970 scopus 로고
    • Human lower oesophageal sphincter relaxation is associated with raised cyclic nucleotide content
    • Barnette, M. S., F. C. Barone, P. J. Fowler, M. Grous, W. J. Price, and H. S. Ormsbee. Human lower oesophageal sphincter relaxation is associated with raised cyclic nucleotide content. Gut 32: 4-9, 1991.
    • (1991) Gut , vol.32 , pp. 4-9
    • Barnette, M.S.1    Barone, F.C.2    Fowler, P.J.3    Grous, M.4    Price, W.J.5    Ormsbee, H.S.6
  • 2
    • 0344058763 scopus 로고    scopus 로고
    • Heme-oxygenase 2 (HO-2) distribution in anorectum of opossum: Colocalization with neuronal nitric oxide synthase (nNOS) and vasoactive intestinal polypeptide (VIP)
    • Battish, R., G. Y. Cao, R. B. Lynn, S. Chakder, and S. Rattan. Heme-oxygenase 2 (HO-2) distribution in anorectum of opossum: colocalization with neuronal nitric oxide synthase (nNOS) and vasoactive intestinal polypeptide (VIP) (Abstract). Gastroenterology 114: A719, 1998.
    • (1998) Gastroenterology , vol.114
    • Battish, R.1    Cao, G.Y.2    Lynn, R.B.3    Chakder, S.4    Rattan, S.5
  • 3
    • 0021261121 scopus 로고
    • Vasoactive intestinal polypeptide: A neurotransmitter for lower esophageal sphincter relaxation
    • Biancani, P., J. H. Walsh, and J. Behar. Vasoactive intestinal polypeptide: a neurotransmitter for lower esophageal sphincter relaxation. J. Clin. Invest. 73: 963-967, 1984.
    • (1984) J. Clin. Invest. , vol.73 , pp. 963-967
    • Biancani, P.1    Walsh, J.H.2    Behar, J.3
  • 4
    • 0344489971 scopus 로고    scopus 로고
    • Fundamentals of gastrointestinal pharmacology
    • edited by G. Friedman, E. D. Jacobson, and R. W. McCallum. Philadelphia, PA: Lippincott-Raven
    • Burks, T. F. Fundamentals of gastrointestinal pharmacology. In: Gastrointestinal Pharmacology and Therapeutics, edited by G. Friedman, E. D. Jacobson, and R. W. McCallum. Philadelphia, PA: Lippincott-Raven, 1997, p. 1-20.
    • (1997) Gastrointestinal Pharmacology and Therapeutics , pp. 1-20
    • Burks, T.F.1
  • 5
    • 0030768127 scopus 로고    scopus 로고
    • Evidence for a nonneural electrogenic effect of cholera toxin on human isolated ileal mucosa
    • Burleigh, D. E., and R. A. Borman. Evidence for a nonneural electrogenic effect of cholera toxin on human isolated ileal mucosa. Dig. Dis. Sci. 42: 1964-1968, 1997.
    • (1997) Dig. Dis. Sci. , vol.42 , pp. 1964-1968
    • Burleigh, D.E.1    Borman, R.A.2
  • 6
    • 0008179315 scopus 로고    scopus 로고
    • Distribution of heme oxygenase-2 (HO-2) in the internal anal sphincter (IAS) of opossum
    • Chakder, S., G. Y. Cao, R. B. Lynn, and S. Rattan. Distribution of heme oxygenase-2 (HO-2) in the internal anal sphincter (IAS) of opossum (Abstract). Gastroenterology 112: A1138, 1997.
    • (1997) Gastroenterology , vol.112
    • Chakder, S.1    Cao, G.Y.2    Lynn, R.B.3    Rattan, S.4
  • 7
    • 0030433676 scopus 로고    scopus 로고
    • Heme oxygenase inhibitor zinc protoporphyrin IX causes an activation of nitric oxide synthase in the rabbit internal anal sphincter
    • Chakder, S., S. Rathi, X. Ma, and S. Rattan. Heme oxygenase inhibitor zinc protoporphyrin IX causes an activation of nitric oxide synthase in the rabbit internal anal sphincter. J. Pharmacol. Exp. Ther. 277: 1376-1382, 1996.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1376-1382
    • Chakder, S.1    Rathi, S.2    Ma, X.3    Rattan, S.4
  • 8
    • 0027436484 scopus 로고
    • The entire vasoactive intestinal polypeptide molecule is required for the activation of the vasoactive intestinal polypeptide receptor: Functional and binding studies on opossum internal anal sphincter smooth muscle
    • Chakder, S., and S. Rattan. The entire vasoactive intestinal polypeptide molecule is required for the activation of the vasoactive intestinal polypeptide receptor: functional and binding studies on opossum internal anal sphincter smooth muscle. J. Pharmacol. Exp. Ther. 266: 392-399, 1993.
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 392-399
    • Chakder, S.1    Rattan, S.2
  • 9
    • 0027238370 scopus 로고
    • Involvement of cAMP and cGMP in relaxation of internal anal sphincter by neural stimulation, VIP, and NO
    • Gastrointest. Liver Physiol. 27
    • Chakder, S., and S. Rattan. Involvement of cAMP and cGMP in relaxation of internal anal sphincter by neural stimulation, VIP, and NO. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G702-G707, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Chakder, S.1    Rattan, S.2
  • 10
    • 0029029765 scopus 로고
    • Distinct muscarinic receptors and signal transduction pathways in gallbladder muscle
    • Chen, Q., P. Yu, G. De Petris, P. Biancani, and J. Behar. Distinct muscarinic receptors and signal transduction pathways in gallbladder muscle. J. Pharmacol. Exp. Ther. 273: 650-655, 1995.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 650-655
    • Chen, Q.1    Yu, P.2    De Petris, G.3    Biancani, P.4    Behar, J.5
  • 11
    • 0028278151 scopus 로고
    • Oxidation of critical cystein residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin
    • Duhe, R. J., M. D. Nielsen, A. H. Dittman, E. C. Villacres, E. J. Choi, and D. R. Storm. Oxidation of critical cystein residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin. J. Biol. Chem. 269: 7290-7296, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 7290-7296
    • Duhe, R.J.1    Nielsen, M.D.2    Dittman, A.H.3    Villacres, E.C.4    Choi, E.J.5    Storm, D.R.6
  • 12
    • 0030442725 scopus 로고    scopus 로고
    • Muscarinic receptor subtypes and smooth muscle function
    • Eglen, R. M., S. S. Hedge, and N. Watson. Muscarinic receptor subtypes and smooth muscle function. Pharmacol. Rev. 48: 531-565, 1996.
    • (1996) Pharmacol. Rev. , vol.48 , pp. 531-565
    • Eglen, R.M.1    Hedge, S.S.2    Watson, N.3
  • 13
    • 0031863477 scopus 로고    scopus 로고
    • Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists
    • Fan, Y. P., S. Chakder, and S. Rattan. Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists. J. Pharmacol. Exp. Ther. 285: 468-474, 1998.
    • (1998) J. Pharmacol. Exp. Ther. , vol.285 , pp. 468-474
    • Fan, Y.P.1    Chakder, S.2    Rattan, S.3
  • 14
    • 0008224941 scopus 로고    scopus 로고
    • Heme oxygenase (HO) inhibitor ZN protoporphyrin IX (ZnPP IX) blocks the actions of vasoactive intestinal polypeptide (VIP) by inhibiting G-protein-coupled receptor binding
    • Fan, Y. P., S. Chakder, and S. Rattan. Heme oxygenase (HO) inhibitor ZN protoporphyrin IX (ZnPP IX) blocks the actions of vasoactive intestinal polypeptide (VIP) by inhibiting G-protein-coupled receptor binding (Abstract). Gastroenterology 114: A750, 1998.
    • (1998) Gastroenterology , vol.114
    • Fan, Y.P.1    Chakder, S.2    Rattan, S.3
  • 15
    • 0027196064 scopus 로고
    • Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide
    • Gastrointest. Liver Physiol. 27
    • Farrugia, G., W. A. Irons, J. L. Rae, M. G. Sarr, and J. H. Szurszewski. Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G1184-G1189, 1993.
    • (1993) Am. J. Physiol. , vol.264
    • Farrugia, G.1    Irons, W.A.2    Rae, J.L.3    Sarr, M.G.4    Szurszewski, J.H.5
  • 16
    • 0026034934 scopus 로고
    • Endothelium-dependent and -independent vasodilation involving cyclic GMP: Relaxation induced by nitric oxide, carbon monoxide and light
    • Furchgott, R. F., and D. Jothianandan. Endothelium-dependent and -independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels 28: 52-61, 1991.
    • (1991) Blood Vessels , vol.28 , pp. 52-61
    • Furchgott, R.F.1    Jothianandan, D.2
  • 17
    • 0021227705 scopus 로고
    • Pharmacologic identification, activation, and antagonism of two muscarine receptor subtypes in the lower esophageal sphincter
    • Gilbert, R. J., S. Rattan, and R. K. Goyal. Pharmacologic identification, activation, and antagonism of two muscarine receptor subtypes in the lower esophageal sphincter. J. Pharmacol. Exp. Ther. 230: 284-291, 1984.
    • (1984) J. Pharmacol. Exp. Ther. , vol.230 , pp. 284-291
    • Gilbert, R.J.1    Rattan, S.2    Goyal, R.K.3
  • 18
    • 18244424743 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase activation by vasoactive intestinal peptide in bovine cerebral arteries
    • Gonzalez, C., C. Barroso, C. Martin, S. Gulbenkian, and C. Estrada. Neuronal nitric oxide synthase activation by vasoactive intestinal peptide in bovine cerebral arteries. J. Cereb. Blood Flow Metab. 17: 977-984, 1997.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 977-984
    • Gonzalez, C.1    Barroso, C.2    Martin, C.3    Gulbenkian, S.4    Estrada, C.5
  • 19
    • 0024437944 scopus 로고
    • Muscarinic receptor subtypes: Physiology and clinical implications
    • Goyal, R. K. Muscarinic receptor subtypes: physiology and clinical implications. N. Engl. J. Med. 321: 1022-1029, 1989.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 1022-1029
    • Goyal, R.K.1
  • 20
    • 0019215005 scopus 로고
    • VIP as a possible neurotransmitter of non-cholinergic non-adrenergic inhibitory neurones
    • Goyal, R. K., S. Rattan, and S. I. Said. VIP as a possible neurotransmitter of non-cholinergic non-adrenergic inhibitory neurones. Nature 288: 378-380, 1980.
    • (1980) Nature , vol.288 , pp. 378-380
    • Goyal, R.K.1    Rattan, S.2    Said, S.I.3
  • 21
    • 0030834118 scopus 로고    scopus 로고
    • Pitfalls using metalloporphyrins in carbon monoxide research
    • Grundemar, L., and L. Ny. Pitfalls using metalloporphyrins in carbon monoxide research. Trends Pharmacol. Sci. 18: 193-195, 1997.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 193-195
    • Grundemar, L.1    Ny, L.2
  • 22
    • 0030974622 scopus 로고    scopus 로고
    • Tailoring cAMP-signalling responses through isoform multiplicity
    • Houslay, M. D., and G. Milligan. Tailoring cAMP-signalling responses through isoform multiplicity. Trends Biochem. Sci. 22: 217-224, 1997.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 217-224
    • Houslay, M.D.1    Milligan, G.2
  • 23
    • 0021250807 scopus 로고    scopus 로고
    • Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulation component of adenylate cyclase by cholera toxin
    • Kahl, R. A., and A. G, Gilman. Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulation component of adenylate cyclase by cholera toxin. J. Biol. Chem. 259: 6228-6234, 1997.
    • (1997) J. Biol. Chem. , vol.259 , pp. 6228-6234
    • Kahl, R.A.1    Gilman, A.G.2
  • 24
    • 0028900016 scopus 로고
    • Ca channels in the muscarinic and β-adrenergic regulation of airway smooth muscle
    • Lung Cell. Mol. Physiol. 12
    • Ca channels in the muscarinic and β-adrenergic regulation of airway smooth muscle. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L221-L229, 1995.
    • (1995) Am. J. Physiol. , vol.268
    • Kume, H.1    Mikawa, K.2    Takagi, K.3    Kotlikoff, M.I.4
  • 26
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • Maines, M. D. The heme oxygenase system: a regulator of second messenger gases. Annu. Rev. Pharmacol. Toxicol. 37: 517-554, 1997.
    • (1997) Annu. Rev. Pharmacol. Toxicol. , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 27
    • 0024269104 scopus 로고
    • Effect of methylene blue and N-ethylmaleimide on internal anal sphincter relaxation
    • Gastrointest. Liver Physiol. 18
    • Moummi, C., and S. Rattan. Effect of methylene blue and N-ethylmaleimide on internal anal sphincter relaxation. Am. J. Physiol. 255 (Gastrointest. Liver Physiol. 18): G571-G578, 1988.
    • (1988) Am. J. Physiol. , vol.255
    • Moummi, C.1    Rattan, S.2
  • 28
    • 0030010051 scopus 로고    scopus 로고
    • Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter
    • Ny, L., P. Alm, P. Ekstrom, B. Larsson, L. Grundemar, and K.-E. Andersson. Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter. Br. J. Pharmacol. 118: 392-399, 1996.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 392-399
    • Ny, L.1    Alm, P.2    Ekstrom, P.3    Larsson, B.4    Grundemar, L.5    Andersson, K.-E.6
  • 29
    • 0029014720 scopus 로고
    • Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase
    • Ny, L., K.-E. Andersson, and L. Grundemar. Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase. Br. J. Pharmacol. 115: 186-190, 1995.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 186-190
    • Ny, L.1    Andersson, K.-E.2    Grundemar, L.3
  • 30
    • 0028878918 scopus 로고
    • Descending peristaltic reflex in the opossum esophagus
    • Gastrointest. Liver Physiol. 32
    • Paterson, W. G., and B. Indrakrishnan. Descending peristaltic reflex in the opossum esophagus. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G219-G224, 1995.
    • (1995) Am. J. Physiol. , vol.269
    • Paterson, W.G.1    Indrakrishnan, B.2
  • 31
    • 0027428932 scopus 로고
    • Inhibitory effect of CO on internal anal sphincter: Heme oxygenase inhibitor inhibits NANC relaxation
    • Gastrointest. Liver Physiol. 28
    • Rattan, S., and S. Chakder. Inhibitory effect of CO on internal anal sphincter: heme oxygenase inhibitor inhibits NANC relaxation. Am. J. Physiol. 265 (Gastrointest. Liver Physiol. 28): G799-G804, 1993.
    • (1993) Am. J. Physiol. , vol.265
    • Rattan, S.1    Chakder, S.2
  • 32
    • 0024554484 scopus 로고
    • Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter
    • Rattan, S., and C. Moummi. Influence of stimulators and inhibitors of cyclic nucleotides on lower esophageal sphincter. J. Pharmacol. Exp. Ther. 248: 703-709, 1989.
    • (1989) J. Pharmacol. Exp. Ther. , vol.248 , pp. 703-709
    • Rattan, S.1    Moummi, C.2
  • 33
    • 0025726184 scopus 로고
    • CGRP and ANF cause relaxation of opossum internal anal sphincter via different mechanisms
    • Gastrointest. Liver Physiol. 23
    • Rattan, S., C. Moummi, and S. Chakder. CGRP and ANF cause relaxation of opossum internal anal sphincter via different mechanisms. Am. J. Physiol. 260 (Gastrointest. Liver Physiol. 23): G764-G769, 1991.
    • (1991) Am. J. Physiol. , vol.260
    • Rattan, S.1    Moummi, C.2    Chakder, S.3
  • 34
    • 0000348139 scopus 로고    scopus 로고
    • Immunocytochemical localization of heme oxygenase-2 and co-localization with nitric oxide synthase in myenteric neurons in human stomach and jejunum
    • Reed, D., S. M. Miller, G. Farrugia, M. G. Sarr, and J. H. Szurszewski. Immunocytochemical localization of heme oxygenase-2 and co-localization with nitric oxide synthase in myenteric neurons in human stomach and jejunum (Abstract). Gastroenterology 110: A7664, 1996.
    • (1996) Gastroenterology , vol.110
    • Reed, D.1    Miller, S.M.2    Farrugia, G.3    Sarr, M.G.4    Szurszewski, J.H.5
  • 35
    • 0002762924 scopus 로고    scopus 로고
    • Pharmacodynamics: Mechanisms of drug action and the relationship between drug concentration and effect
    • edited by J. G. Hardman, L. E. Limbird, P. B. Molinoff, R. W. Ruddon, and A. G. Gilman. New York: McGraw Hill
    • Ross, E. M. Pharmacodynamics: mechanisms of drug action and the relationship between drug concentration and effect. In: Goodman & Gilman's The Pharmacological Basis of Therapeutics, edited by J. G. Hardman, L. E. Limbird, P. B. Molinoff, R. W. Ruddon, and A. G. Gilman. New York: McGraw Hill, 1996, p. 29-41.
    • (1996) Goodman & Gilman's the Pharmacological Basis of Therapeutics , pp. 29-41
    • Ross, E.M.1
  • 36
    • 0025122931 scopus 로고
    • VIP-induced alterations in cAMP and inositol phosphates in the lower esophageal sphincter
    • Gastrointest. Liver Physiol. 22
    • Szewczak, S. M., J. Behar, G. Billett, C. Hillemeier, B. Y. Rhim, and P. Biancani. VIP-induced alterations in cAMP and inositol phosphates in the lower esophageal sphincter. Am. J. Physiol. 259 (Gastrointest. Liver Physiol. 22): G239-G244, 1990.
    • (1990) Am. J. Physiol. , vol.259
    • Szewczak, S.M.1    Behar, J.2    Billett, G.3    Hillemeier, C.4    Rhim, B.Y.5    Biancani, P.6
  • 37
    • 0029053946 scopus 로고
    • Pharmacological identification of different inhibitory mediators involved in the innervation of the internal anal sphincter
    • Tottrup, A., M. A. Knudsen, F. H. Sorensen, and E. B. Glavind. Pharmacological identification of different inhibitory mediators involved in the innervation of the internal anal sphincter. Br. J. Pharmacol. 115: 158-162, 1995.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 158-162
    • Tottrup, A.1    Knudsen, M.A.2    Sorensen, F.H.3    Glavind, E.B.4
  • 38
    • 0027467004 scopus 로고
    • The role of cyclic adenosine monophosphate, cyclic guanosine monophosphate, endothelium and nonadrenergic, noncholinergic neurotransmission in canine penile erection
    • Trigo-Rocha, F., G. L. Hsu, C. F. Donatucci, and T. F. Lue. The role of cyclic adenosine monophosphate, cyclic guanosine monophosphate, endothelium and nonadrenergic, noncholinergic neurotransmission in canine penile erection. J. Urol. 149: 872-877, 1993.
    • (1993) J. Urol. , vol.149 , pp. 872-877
    • Trigo-Rocha, F.1    Hsu, G.L.2    Donatucci, C.F.3    Lue, T.F.4
  • 39
    • 0028073463 scopus 로고
    • Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons
    • Vincent, S. R., S. Das, and M. D. Maines. Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons. Neuroscience 63: 223-231, 1994.
    • (1994) Neuroscience , vol.63 , pp. 223-231
    • Vincent, S.R.1    Das, S.2    Maines, M.D.3
  • 40
    • 0026571817 scopus 로고
    • Role of nitric oxide in lower esophageal sphincter relaxation to swallowing
    • Yamato, S., J. K. Saha, and R. K. Goyal. Role of nitric oxide in lower esophageal sphincter relaxation to swallowing. Life Sci. 50: 1263-1272, 1992.
    • (1992) Life Sci. , vol.50 , pp. 1263-1272
    • Yamato, S.1    Saha, J.K.2    Goyal, R.K.3
  • 41
    • 0029665853 scopus 로고    scopus 로고
    • Effects of cAMP elevating agents on carbachol-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells
    • Yang, C. M., M. C. Hsu, H. L. Tsao, C. T. Chiu, R. Ong, J.-T. Hsieh, and L. W. Fan. Effects of cAMP elevating agents on carbachol-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells. Cell Calcium 19: 243-254, 1996.
    • (1996) Cell Calcium , vol.19 , pp. 243-254
    • Yang, C.M.1    Hsu, M.C.2    Tsao, H.L.3    Chiu, C.T.4    Ong, R.5    Hsieh, J.-T.6    Fan, L.W.7


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