Localization and activity of haem oxygenase and functional effects of carbon monoxide in the feline lower oesophageal sphincter

British Journal of Pharmacology

Volumn 118, Issue 2, 1996, Pages 392-399

  Ny, Lars ^a   Alm, Per ^a   Ekström, Peter ^b   Larsson, Bengt ^a   Grundemar, Lars ^a   Andersson, Karl Erik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Carbon monoxide; Haem oxygenase; Metalloporphyrins; Nitric oxide synthase; Nonadrenergic; Noncholinergic nerves; Oesophagogastric junction; Peptide histidine isoleucine; Pituitary adenylate cyclase activating peptide; Smooth muscle; Vasoactive intestinal peptide

Indexed keywords

CARBON MONOXIDE; CYCLIC GMP; ENZYME INHIBITOR; HEME OXYGENASE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; METHYLENE BLUE; NITRIC OXIDE SYNTHASE; PEPTIDE HISTIDINE ISOLEUCINE; PROTOPORPHYRIN TIN; PROTOPORPHYRIN ZINC; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CAT; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME HISTOCHEMISTRY; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; LOWER ESOPHAGUS SPHINCTER; MALE; MYENTERIC PLEXUS; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; SMOOTH MUSCLE RELAXATION; TISSUE DISTRIBUTION;

EID: 0030010051     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15415.x     Document Type: Article

References (41)

1. BRADFORD, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt. Biochem., 72, 248-254.
2. CAVALLIN-STȦHL, E., JÖNSSON, G.-I. & LUNDH, B. (1978). A new method for determination of microsomal haem oxygenase /EC 1.14.99.3) based on quantitation of carbon monoxide formation. Scand. J. Clin. Lab. Invest., 38, 69-76.
3. COOK, M.N., NAKATSU, K., MARKS, G.S., MCLAUGHLIN, B.E., VREMAN, H.J., STEVENSON, D.K. & BRIEN, J.F. (1995). Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation. Can. J. Physiol. Pharmacol., 73, 515-518.
4. DANIEL, E.E. & BEREZIN, I. (1992). Interstitial cells of Cajal: are they major players in control of gastrointestinal motility? J. Gastrointest. Motil., 4, 1-24.
5. DAWSON, T.M. & SNYDER, S.H. (1994). Gases as biological messengers: nitric oxide and carbon monoxide in the brain. J. Neurosci., 14, 5147-5159.
6. DWYER, B.E., NISHIMURA, R.N. & LU, S.-Y. (1995). Differential localization of heme oxygenase and NADPH-diaphorase in spinal cord neurons. Neuroreport, 6, 973-976.
7. EWING, J.F. & MAINES, M.D. (1992). In situ hybridization and immunohistochemical localization of heme oxygenase-2 mRNA and protein in normal rat brain: Differential distribution of isozyme 1 and 2. Mol. Cell Neurosci., 3, 559-570.
8. EWING, J.F., RAJU, V.S. & MAINES, M.D. (1994). Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3′:5′-guanosine monophosphate. J. Pharmacol. Exp. Ther., 27, 408-414.
9. FARRUGIA, G., IRONS, W.A., RAE, J.L., SARR, M.G. & SZURSZEWSKI, J.H. (1993). Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide. Am. J. Physiol., 264, G1184-G1189.
10. FURCHGOTT, R.F. & JOTHIANANDAN, S. (1991). Endothelium-dependent and -independent vasodilatation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide and light. Blood Vessels, 28, 52-61.
11. GRUNDEMAR, L., JOHANSSON, M.-B., EKELUND, M. & HÖGESTÄTT, E.D. (1995). Heme oxygenase activity in blood vessel homogenates as measured by carbon monoxide production. Acta Physiol. Scand., 153, 203-204.
12. IGNARRO, L.J., BALLOT, B. & WOOD, K.S. (1984). Regulation of soluble guanylate cyclase activity by porphyrins and metalloporphyrins. J. Biol. Chem., 259, 6201-6207.
13. JOHNSON, G.D. & ARAUJO, G.M. (1981). A simple method of reducing the fading of immunofluorescence during microscopy. J. Immunol. Methods, 43, 349-350.
14. LEFER, D.J., MA, X-I. & LEFER, M. (1993). A comparison of vascular biological actions of carbon monoxide and nitric oxide. Meth. Find. Clin. Pharmacol., 15, 617-622.
15. LINDEN, D.J., NARASIMAN, K. & GURFEL, D. (1993). Protoporphyrins modulate voltage-gated Ca Current in AtT-20 pituitary cells. J. Neurophysiol., 70, 2673-2677.
16. LUO, D. & VINCENT, S.R. (1994). Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur. J. Pharmacol., 267, 263-267.
17. MAINES, M.D. (1988). Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J., 2, 2557-2568.
18. MAINES, M.D. (1993). Carbon monoxide: an emerging regulator of cGMP in the brain. Mol. Cell. Neurosci., 4, 389-397.
19. MAINES, M.D., MARK, J.A. & EWING, J.F. (1993). Heme oxygenase, a likely regulator of cGMP production in the brain: Induction in vivo of HO-1 compensates for depression in NO synthase activity. Mol. Cell. Neurosci., 4, 398-405.
20. MAYER, B. (1994). Nitric oxide/cyclic GMP-mediated signal transduction. Ann. N.Y. Acad. Sci., 733, 357-364.
21. MEFFERT, M.K., HALEY, J.E., SCHUMAN, E.M., SCHULMAN, H. & MADISON, D.V. (1994). Inhibition of hippocampal heme oxygenase, nitric oxide synthase, and long-term potentiation by metalloporphyrins. Neuron, 13, 1225-1233.
22. MORITA, T., PERRELLA, M.A., LEE, M.-E. & KOUREMBANAS, S. (1995). Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc. Natl. Acad. Sci. U.S.A., 92, 1475-1479.
23. NY, L., ALM, P., LARSSON, B., EKSTRÖM, P. & ANDERSSON, K-E. (1995a). Nitric oxide pathway in cat esophagus: localization of nitric oxide synthase and functional effects. Am. J. Physiol., 268, G59-G70.
24. NY, L., ANDERSSON, K.-E. & GRUNDEMAR, L. (1995b). Inhibition by zinc protoporphyrin-IX of receptor-mediated relaxation of the rat aorta in a manner distinct from inhibition of haem oxygenase. Br. J. Pharmacol., 115, 186-190.
25. NY, L., GRUNDEMAR, L., LARSSON, B., ALM, P., EKSTRÖM, P. & ANDERSSON, K.-E. (1995c). Carbon monoxide as a putative messenger molecule in the feline lower oesophageal sphincter. Neuroreport, 6, 1261-1265.
26. PRABHAKAR, N.R., DINERMAN, J.L., AGANI, F.H. & SNYDER, S.H. (1995). Carbon monoxide: a role in carotid body chemoreception. Proc. Natl. Acad. Sci. U.S.A. 92, 1994-1997.
27. RAND, M.J. & LI, C.G. (1995). Nitric oxide as a neurotransmitter in peripheral nerves: nature of transmitter and mechanism of transmission. Annu. Rev. Physiol., 57, 659-682.
28. RATTAN, S. & CHAKDER, S. (1993). Inhibitory effect of CO on internal anal sphincter: heme oxygenase inhibitor inhibits NANC relaxation. Am. J. Physiol., 265, G-799-G804.
29. SHINOMURA, T., NAKO, S.-I. & MORI, K. (1994). Reduction of depolarization-induced glutamate release by heme oxygenase inhibitor: possible role of carbon monoxide in synaptic transmission. Neurosci. Lett., 166, 131-134.
30. STEVENS, C.F. & WANG, Y. (1993). Reversal of long-term potentiation by inhibitors of haem oxygenase. Nature, 364, 147-149.
31. STONE, J.R. & MARLETTA, M.A. (1994). Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. Biochemistry, 33, 5636-5640.
32. TØTTRUP, A., KNUDSEN, M.A., HANBERG SØRENSEN, F. & GLAVIND, E.B. (1995). Pharmacological identification of different inhibitory mediators involved in the innervation of the internal anal sphincter. Br. J. Pharmacol., 115, 158-162.
33. UTZ, J. & ULLRICH, V. (1991). Carbon monoxide relaxes ileal smooth muscle through activation of guanylate cyclase. Biochem. Pharmacol., 41, 1195-1201.
34. VERMA, A., HIRSCH, D.J., GLATT, C.E., RONETT, G.V. & SNYDER, S.H. (1993). Carbon monoxide: a putative neuronal messenger. Science, 259, 381-384.
35. VINCENT, S.R., DAS, S. & MAINES, M.D. (1994). Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons. Neuroscience, 63, 223-231.
36. VREMAN, H.J., GILLMAN, M.J. & STEVENSON, D.K. (1989). In vitro inhibition of adult rat intestinal heme oxygenase by metalloporphyrins. Pediatr. Res., 26, 362-365.
37. VREMAN, H.J. & STEVENSON, D.K. (1988). Heme oxygenase activity as measured by carbon monoxide production. Anal. Biochem., 168, 31-38.
38. WESSENDORF, M.W. & ELDE, R.P. (1985). Characterization of an immunofluoresence technique for the demonstration of coexisting neuro-transmitters within nerve fibres and terminals. J. Histochem. Cytochem., 33, 984-994.
39. ZHANG, J. & SNYDER, S.H. (1995). Nitric oxide in the nervous system. Annu. Rev. Pharmacol. Toxicol., 35, 213-233.
40. ZHUO, M., SMALL, S.A., KANDEL, E.R. & HAWKINS, R.D. (1993). Nitric oxide and carbon monoxide produce activity-dependent long-term synaptic enhancement in hippocampus. Science, 260, 1946-1950.
41. ZYGMUNT, P.M., HÖGESTÄTT, E.D. & GRUNDEMAR, L. (1994). Light-dependent effects of zinc protoporphyrin IX on endothelium-dependent relaxation resistant to Nω-nitro-L-arginine. Acta Physiol. Scand., 152, 137-143.