Metallothionein-I/II knockout mice are sensitive to acetaminophen- induced hepatotoxicity

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 1, 1999, Pages 580-586

  Liu, Jie ^a,c   Liu, Yaping ^a   Hartley, Dylan ^a   Klaassen, Curtis D ^a   Shehin Johnson, Stacey E ^b   Lucas, Angela ^b   Cohen, Steven D ^b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GLUTATHIONE; METALLOTHIONEIN; PARACETAMOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HISTOPATHOLOGY; IMMUNOBLOTTING; INTRAPERITONEAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; LIPID PEROXIDATION; LIVER CYTOSOL; LIVER FUNCTION; LIVER TOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; BIOTRANSFORMATION; GLUTATHIONE; HEPATITIS, TOXIC; LIPID PEROXIDATION; LIVER; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS;

EID: 0032943471     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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