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Volumn 19, Issue 5, 1999, Pages 1316-1324

Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease

Author keywords

Familial hyperhomocysteinemia; Homocysteine; Methionine loading test; Methylenetetrahydrofolate reductase; Premature vascular disease; Vitamins

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CREATININE; FOLIC ACID; HOMOCYSTEINE; METHIONINE;

EID: 0032943256     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.19.5.1316     Document Type: Article
Times cited : (24)

References (51)
  • 4
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: Probable benefits of increasing folic acid intakes
    • Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease: probable benefits of increasing folic acid intakes. JAMA. 1995;274: 1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 5
    • 0029019141 scopus 로고
    • Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: Initial results from the NHLBI family heart study
    • Bostom AG, Jacques PF, Nadeau MR, Williams RR, Ellison RC, Selhub J. Post-methionine load hyperhomocysteinemia in persons with normal fasting total plasma homocysteine: initial results from The NHLBI Family Heart Study. Atherosclerosis. 1995;116:147-151.
    • (1995) Atherosclerosis , vol.116 , pp. 147-151
    • Bostom, A.G.1    Jacques, P.F.2    Nadeau, M.R.3    Williams, R.R.4    Ellison, R.C.5    Selhub, J.6
  • 7
    • 0030053145 scopus 로고    scopus 로고
    • Plasma homocysteine and severity of atherosclerosis in young patients with lower-limb atherosclerotic disease
    • Van den Berg M, Stehouwer CDA, Bierdrager E, Rauwerda JA. Plasma homocysteine and severity of atherosclerosis in young patients with lower-limb atherosclerotic disease. Arterioscler Thromb Vasc Biol. 1996; 16:165-171.
    • (1996) Arterioscler Thromb Vasc Biol. , vol.16 , pp. 165-171
    • Van Den Berg, M.1    Stehouwer, C.D.A.2    Bierdrager, E.3    Rauwerda, J.A.4
  • 10
    • 0030811925 scopus 로고    scopus 로고
    • Genetic predisposition to hyperhomocysteinemia: Deficiency of methylenetetrahydrofolate reductase (MTHFR)
    • Rozen R. Genetic predisposition to hyperhomocysteinemia: deficiency of methylenetetrahydrofolate reductase (MTHFR). Thromb Haemost. 1997; 78:523-526.
    • (1997) Thromb Haemost. , vol.78 , pp. 523-526
    • Rozen, R.1
  • 11
    • 0030712992 scopus 로고    scopus 로고
    • Plasma total homocysteine in a representative sample of 972 british men and women aged 65 and over
    • Bates CJ, Mansoor MA, van der Pols J, Prentice A, Cole TJ, Finch S. Plasma total homocysteine in a representative sample of 972 British men and women aged 65 and over. Eur J Clin Nutr. 1997;51:691-697.
    • (1997) Eur J Clin Nutr. , vol.51 , pp. 691-697
    • Bates, C.J.1    Mansoor, Ma.2    Van Der Pols, J.3    Prentice, A.4    Cole, T.J.5    Finch, S.6
  • 17
    • 0029968008 scopus 로고    scopus 로고
    • Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction
    • Schmitz C, Lindpaintner K, Verhoef P, Gaziano JM, Buring J. Genetic polymorphism of methylenetetrahydrofolate reductase and myocardial infarction. Circulation. 1996;94:1812-1814.
    • (1996) Circulation , vol.94 , pp. 1812-1814
    • Schmitz, C.1    Lindpaintner, K.2    Verhoef, P.3    Gaziano, J.M.4    Buring, J.5
  • 20
    • 0027421353 scopus 로고
    • Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease
    • Kang SS, Passen EL, Ruggie N, Wong PWK, Sora H. Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease. Circulation. 1993;88:1463-1469.
    • (1993) Circulation , vol.88 , pp. 1463-1469
    • Kang, S.S.1    Passen, E.L.2    Ruggie, N.3    Wong, P.W.K.4    Sora, H.5
  • 21
  • 22
    • 0029974036 scopus 로고    scopus 로고
    • Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (≥40 μmol/liter). The Hordaland homocysteine study
    • Guttormsen AB, Ueland PM, Nesthus I, Nygård O, Schneede J, Vollset SE, Refsum H. Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (≥40 μmol/liter). The Hordaland Homocysteine Study. J Clin Invest. 1996;98:2174-2183.
    • (1996) J Clin Invest. , vol.98 , pp. 2174-2183
    • Guttormsen, A.B.1    Ueland, P.M.2    Nesthus, I.3    Nygård, O.4    Schneede, J.5    Vollset, S.E.6    Refsum, H.7
  • 23
    • 0023892344 scopus 로고
    • Thermo-labile methylenetetrahydrofolate reductase in patients with coronary artery disease
    • Kang SS, Wong PWK, Zhou J, Sora J, Lessick M, Ruggie N, Grcevich G. Thermo-labile methylenetetrahydrofolate reductase in patients with coronary artery disease. Metabolism. 1988;37:611-613.
    • (1988) Metabolism , vol.37 , pp. 611-613
    • Kang, S.S.1    Wong, P.W.K.2    Zhou, J.3    Sora, J.4    Lessick, M.5    Ruggie, N.6    Grcevich, G.7
  • 24
    • 0028670786 scopus 로고
    • Homocyst(e)ine and arterial occlusive diseases (Frontiers in medicine)
    • Malinow MR. Homocyst(e)ine and arterial occlusive diseases (Frontiers in Medicine). J Intern Med. 1994;236:603-617.
    • (1994) J Intern Med. , vol.236 , pp. 603-617
    • Malinow, M.R.1
  • 32
    • 0021968758 scopus 로고
    • Stability of pyridoxal-5-phosphate semicarbazone; applications in plasma vitamin b6 analysis and population surveys of vitamin B6 nutritional status
    • Ubbink JB, Serfontein WJ, de Villiers LS. Stability of pyridoxal-5-phosphate semicarbazone; applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional status. J Chromatogr. 1985; 342:277-284.
    • (1985) J Chromatogr. , vol.342 , pp. 277-284
    • Ubbink, J.B.1    Serfontein, W.J.2    De Villiers, L.S.3
  • 33
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 34
    • 0030612756 scopus 로고    scopus 로고
    • The 677 C→T mutation in the methylenetetrahydrofolate reductase gene: Associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease
    • Verhoef P, Kok FJ, Kluijtmans LAJ, Blom HJ, Refsum H, Ueland PM, Kruyssen DACM. The 677 C→T mutation in the methylenetetrahydrofolate reductase gene: associations with plasma total homocysteine levels and risk of coronary atherosclerotic disease. Atherosclerosis. 1997;132: 105-113.
    • (1997) Atherosclerosis , vol.132 , pp. 105-113
    • Verhoef, P.1    Kok, F.J.2    Kluijtmans, L.A.J.3    Blom, H.J.4    Refsum, H.5    Ueland, P.M.6    Kruyssen, D.A.C.M.7
  • 37
    • 0031049530 scopus 로고    scopus 로고
    • A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of coronary artery disease or myocardial infarction
    • Brugada R, Marian AJ. A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of coronary artery disease or myocardial infarction. Atherosclerosis. 1997;128:107-112.
    • (1997) Atherosclerosis , vol.128 , pp. 107-112
    • Brugada, R.1    Marian, A.J.2
  • 41
    • 0021072739 scopus 로고
    • Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive years
    • Boers GH, Smals AG, Trijbels FJ, Leermakers AI, Kloppenborg PW. Unique efficiency of methionine metabolism in premenopausal women may protect against vascular disease in the reproductive years. J Clin Invest. 1983;72:1971-1976.
    • (1983) J Clin Invest. , vol.72 , pp. 1971-1976
    • Boers, G.H.1    Smals, A.G.2    Trijbels, F.J.3    Leermakers, A.I.4    Kloppenborg, P.W.5
  • 42
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA. 1993;270:2693-2698.
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.F.3    Rush, D.4    Rosenberg, I.H.5
  • 43
    • 0026552225 scopus 로고
    • Hyperhomocysteinemia in stroke: Prevalence, cause and relationships to type of stroke and stroke risk factors
    • Brattström L, Lindgren A, Israelsson B, Malinow MR, Norrving B, Upson B. Hyperhomocysteinemia in stroke: prevalence, cause and relationships to type of stroke and stroke risk factors. Eur J Clin Invest. 1992;22:214-221.
    • (1992) Eur J Clin Invest. , vol.22 , pp. 214-221
    • Brattström, L.1    Lindgren, A.2    Israelsson, B.3    Malinow, M.R.4    Norrving, B.5    Upson, B.6
  • 44
    • 0025095390 scopus 로고
    • Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment
    • Brattström L, Israelsson B, Norrving B, Bergqvist D, Thörne J, Hultberg B, Hamfelt A. Impaired homocysteine metabolism in early-onset cerebral and peripheral occlusive arterial disease. Effects of pyridoxine and folic acid treatment. Atherosclerosis. 1990;81:51-60.
    • (1990) Atherosclerosis , vol.81 , pp. 51-60
    • Brattström, L.1    Israelsson, B.2    Norrving, B.3    Bergqvist, D.4    Thörne, J.5    Hultberg, B.6    Hamfelt, A.7
  • 45
    • 0028220787 scopus 로고
    • Vitamin B-6 deficiency vs folate deficiency: Comparison of responses to methionine loading in rats
    • Miller JW, Nadeau MR, Smith D, Selhub J. Vitamin B-6 deficiency vs folate deficiency: comparison of responses to methionine loading in rats. Am J Clin Nutr. 1994;59:1033-1039.
    • (1994) Am J Clin Nutr. , vol.59 , pp. 1033-1039
    • Miller, J.W.1    Nadeau, M.R.2    Smith, D.3    Selhub, J.4
  • 46
    • 0000167774 scopus 로고
    • Disorders of transsulfuration
    • Scriver CR, Beaudet AL, Sly WS, Valle D, eds. New York, NY: McGraw-Hill
    • Mudd SH, Levy HL, Skovby F. Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The metabolic and molecular bases of inherited disease. New York, NY: McGraw-Hill; 1995; 1279-1327.
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , pp. 1279-1327
    • Mudd, S.H.1    Levy, H.L.2    Skovby, F.3
  • 50
    • 0030726498 scopus 로고    scopus 로고
    • Low concentrations of folate in serum and erythrocytes of smokers: Methionine loading decreases folate concentrations in serum of smokers and nonsmokers
    • Mansoor MA, Kirstensen O, Hervig T, Drablos PA, Stakkestad JA, Woie L, Hetland O, Osland A. Low concentrations of folate in serum and erythrocytes of smokers: methionine loading decreases folate concentrations in serum of smokers and nonsmokers. Clin Chem. 1997;43: 2192-2194.
    • (1997) Clin Chem. , vol.43 , pp. 2192-2194
    • Mansoor, M.A.1    Kirstensen, O.2    Hervig, T.3    Drablos, P.A.4    Stakkestad, J.A.5    Woie, L.6    Hetland, O.7    Osland, A.8
  • 51
    • 0030005361 scopus 로고    scopus 로고
    • Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans
    • Colch.
    • Loehrer FMT, Haefeli WE, Angst CP, Browne G, Frick G, Fowler B. Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans. Clin Sci (Colch). 1996;91:79-86.
    • (1996) Clin Sci , vol.91 , pp. 79-86
    • Loehrer, F.M.T.1    Haefeli, W.E.2    Angst, C.P.3    Browne, G.4    Frick, G.5    Fowler, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.