Nitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig

British Journal of Pharmacology

Volumn 126, Issue 1, 1999, Pages 93-102

  Lewis, Karina ^a,b   Cadieux, Alain ^a   Rae, Giies A ^a   Gratton, Jean Philippe ^a   D'Orléans Juste, Pedro ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Eicosanoids; ET(B) receptors; Mean arterial blood pressure; Nitric oxide; Pulmonary insufflation pressure

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ARGININE; BRADYKININ; ENDOTHELIN 1; ENDOTHELIN B RECEPTOR; ICOSANOID; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE]; THROMBOXANE A2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY RESISTANCE; ARTICLE; BRONCHOSPASM; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GUINEA PIG; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; LUNG PERFUSION; LUNG PRESSURE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; AIRWAY RESISTANCE; ANIMALS; ANTIHYPERTENSIVE AGENTS; ARGININE; BLOOD PRESSURE; BRADYKININ; BRONCHOCONSTRICTION; CYCLOOXYGENASE INHIBITORS; DRUG SYNERGISM; EICOSANOIDS; ENDOTHELIN-1; ENDOTHELINS; ENZYME INHIBITORS; FEMALE; GUINEA PIGS; HYPOTENSION; INDOMETHACIN; LUNG; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PERFUSION; PIPERIDINES; THROMBOXANE A2; VASOCONSTRICTOR AGENTS;

EID: 0032943144     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702274     Document Type: Article

References (42)

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