Simple O-acylated derivatives of lysergol and dihydrolysergol-I: Synthesis and interaction with 5-HT(2A), 5-HT(2C) and 5-HT(1B) receptors, and α1 adrenergic receptors

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 3, 1999, Pages 319-330

  Pertz, Heinz H ^a   Brown, Anthony M ^b   Gager, Tracey L ^b   Kaumann, Alberto J ^c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b GLAXOSMITHKLINE   (United Kingdom)

^c BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 ISOPROPYL 6 METHYLERGOLINE 8 CARBOXYLIC ACID 2 HYDROXY 1 METHYLPROPYL ESTER; ALKALOID; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; DIHYDROLYSERGOL DERIVATIVE; ERGOLINE DERIVATIVE; LYSERGOL DERIVATIVE; METHYSERGIDE; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTICLE; CHOROID PLEXUS; COMPETITIVE INHIBITION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; ILIAC ARTERY; MALE; NONHUMAN; RADIOASSAY; RAT; REACTION ANALYSIS; RECEPTOR AFFINITY; TAIL ARTERY;

EID: 0032939716     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991772321     Document Type: Article

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