Glucose regulation of the IGF response system in chondrocytes: Induction of an IGF-I-resistant state

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 276, Issue 4 45-4, 1999, Pages

  Kelley, K M ^a   Johnson, T R ^b   Ilan, J ^b   Moskowitz, R W ^b  

^a CALIFORNIA STATE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cartilage; Insulin like growth factor type I receptor; Insulin like growth factor binding protein; Proteoglycan

Indexed keywords

GLUCOSE; MESSENGER RNA; PROTEOGLYCAN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SULFUR 35;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CHONDROPATHY; CONTROLLED STUDY; DEGENERATIVE DISEASE; FEMALE; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; LIGAND BINDING; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RABBIT; WESTERN BLOTTING;

EID: 0032939604     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.276.4.r1164     Document Type: Article

References (35)

1. Bhaumick, B. Insulin-like growth factor (IGF) binding proteins and insulin-like growth factor secretion by cultured chondrocyte cells: identification, characterization and ontogeny during cell differentiation. Regul. Pept. 48: 113-122, 1993.
2. Burch, W. M., J. Correa, J. E. Shively, and D. R. Powell. The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro. J. Clin. Endocrinol. Metab. 70: 173-180, 1990.
3. Chomczynski, P., and N. Sacchi. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
4. Curtis, A. J., C. K. Ng, C. J. Handley, and H. C. Robinson. Effect of insulin-like growth factor-I on the synthesis and distribution of link protein and hyaluronan in explant cultures of articular cartilage. Biochim. Biophys. Acta 1135: 309-317, 1992.
5. Daughaday, W. H., and P. Rotwein. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structure, serum and tissue concentrations. Endocr. Rev. 10: 68-91, 1989.
6. Demarquay, D., M. F. Dumontier, L. Tsagris, J. Bourguignon, V. Nataf, and M. T. Corvol. In vitro insulin-like growth factor I interaction with cartilage cells derived from postnatal animals. Horm. Res. 33: 111-115, 1990.
7. Denko, C. W., B. Boja, and R. W. Moskowitz. Growth promoting peptides in osteoarthritis and diffuse idiopathic skeletal hyperostosis - insulin, insulin-like growth factor-1, growth hormone. J. Rheumatol. 21: 1725-1730, 1994.
8. Doré, S., J. B. Pelletier, J. A. DiBattista, G. Tardiff, P. Brazeau, and J. Martel-Pelletier. Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins. Arthritis Rheum. 37: 253-263, 1994.
9. English, D. E., C. L. Barnum, S. M. Russell, and C. S. Nicoll. Hypophysectomy partially restores the responsiveness of diabetic rats to growth hormone: further evidence of dissociation between growth responses and serum IGF-I concentration. Endocr. J. 1: 73-78, 1993.
10. Fourschou, P., N. Grunnet, O. Winding, A. Dirksen, and P. Faarup. Rheumatoid arthritis cells and biochemical changes in turpentine-induced pleuritis in rabbits. Acta Pathol. Microbiol. Immunol. Scand. 97: 413-418, 1989.
11. Froger-Gaillard, B., P. Hossenlopp, M. Adolphe, and M. Binoux. Production of insulin-like growth factors and their binding proteins by rabbit articular chondrocytes: relationships with cell multiplication. Endocrinology 124: 2365-2372, 1989.
12. Hawkins, M., N. Barzilai, W. Chen, I. Angelov, W. Hu, P. Cohen, and L. Rossetti. Increased hexosamine availability similarly impairs the action of insulin and IGF-I on glucose disposal. Diabetes 45: 1734-1743, 1996.
13. Hernvann, A., L. Cynober, C. Aussel, and O. G. Ekindjian. Rhuematoid arthritis modifies basal and insulin-mediated glucose uptake by human synoviocytes. Cell. Mol. Biol. (Oxf.) 37: 541-547, 1991.
14. Howell, D. S., and J. P. Pelletier. Ethiopathogenesis of osteoarthritis. In: Arthritis and Allied Conditions (12th ed.), edited by D. J. McCarthy and W. J. Koopman. Philadelphia, PA: Lea and Febiger, 1993, p. 93-147.
15. Hresko, R. C., H. Heimberg, M. M.-Y. Chi, and M. Mueckler. Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. J. Biol. Chem. 273: 20658-20668, 1998.
16. Isaksson, O. G., C. Ohlsson, A. Nilsson, J. Isgaard, and A. Lindahl. Regulation of cartilage growth by growth hormone and insulin-like growth factor-I. Pathology 5: 451-453, 1991.
17. Kelley, K. M., E. S. Gray, K. Siharath, C. S. Nicoll, and H. A. Bern. Diabetes mellitus in a teleost fish. II. Roles of insulin, growth hormone (GH), insulin-like growth factor-I (IGF-I) and hepatic GH receptors in diabetic growth inhibition in the goby, Gillichthys mirabilis. Endocrinology 132: 2696-2702, 1993.
18. Kelley, K. M., Y. Oh, S. E. Gargosky, Z. S. Gucev, T. Matsumoto, V. Hwa, L. Ng, D. M. Simpson, and R. G. Rosenfeld. Insulin-like growth factor-binding proteins (IGFBPs) and their regulatory dynamics. Int. J. Biochem. Cell Biol. 28: 619-637, 1996.
19. Kelley, K. M., S. M. Russell, M. L. Matteucci, and C. S. Nicoll. An insulin-like growth factor-I-resistant state in cartilage of diabetic rats is ameliorated by hypophysectomy. Possible role of metabolism. Diabetes 42: 463-469, 1993.
20. Lee, P. D. K., L. C. Guidice, C. A. Conover, and D. R. Powell. Insulin-like growth factor-binding protein-1: recent findings and new directions. Proc. Soc. Exp. Biol. Med. 216: 319-357, 1997.
21. Lehmer, R. R., B. S. Andrews, J. A. Robertson, E. J. Stanbridge, L. de la Maza, and G. J. Friou. Clinical and biological characterization of Ureaplasma urealyticum induced polyarthritis in a patient with common variable hypogammaglobulinaemia. Ann. Rheum. Dis. 50: 574-576, 1991.
22. Leonard, C. M., M. Bergman, D. A. Frenz, L. A. Macreery, and S. A. Newman. Abnormal ambient glucose levels inhibit proteoglycan core protein gene expression and reduce proteoglycan accumulation during chondrogenesis: possible mechanism for teratogenic effects of maternal diabetes. Proc. Natl. Acad. Sci. USA 86: 10113-10117, 1989.
23. Lowry, O. H., N. J. Rosenbrough, A. L. Farr, and R. J. Randall. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
24. Maes, M., L. E. Underwood, and J.-M. Ketelslegers. Low serum somatomedin-C in insulin-dependent diabetes mellitus: evidence for a post-receptor mechanism. Endocrinology 118: 377-382, 1986.
25. Matsumoto, T., S. E. Gargosky, Y. Oh, and R. G. Rosenfeld. Transcriptional and post-translational regulation of insulin-like growth factor binding protein (IGFBP)-5 in rat articular chondrocytes. J. Endocrinol. 148: 355-369, 1996.
26. Moskowitz, R. W., V. M. Goldberg, and C. J. Malemud. Metabolic responses of cartilage in experimentally induced osteoarthritis. Ann. Rheum. Dis. 40: 584-594, 1981.
27. Olney, R. C., R. L. Smith, Y. Kee, and D. M. Wilson. Production and hormonal regulation of insulin-like growth factor binding protiens in bovine chondrocytes. Endocrinology 133: 563-570, 1993.
28. Paolisso, G., G. Valentini, D. Guigliano, G. Marrazzo, R. Tirri, M. Gallo, G. Tirri, M. Varricchio, and F. D'Onofrio. Evidence for peripheral impaired glucose handling in patients with connective tissue diseases. Metabolism 40: 902-907, 1991.
29. Rodgers, B. D., A. O. T. Lau, and C. S. Nicoll. Hypophysectomy or adrenalectomy of rats with insulin-dependent diabetes mellitus partially restores their responsiveness to growth hormone. Proc. Soc. Exp. Biol. Med. 207: 220-226, 1994.
30. Rodgers, B. D., A. M. Strack, M. F. Dallman, L. Hwa, and C. S. Nicoll. Corticosterone regulation of insulin-like growth factor-1, IGF-binding proteins, and growth in streptozotocin-induced diabetic rats. Diabetes 44: 1420-1425, 1995.
31. Schalkwijk, J., L. A. B. Joosten, W. B. van den Berg, and L. B. A. van de Putte. Chondrocyte nonresponsiveness to insulin-like growth factor 1 in experimental arthritis. Arthritis Rheum. 32: 894-900, 1989.
32. Styrud, J., and U. J. Eriksson. In vitro effects of glucose and growth factors on limb bud and mandibular arch chondrocytes maintained at various serum concentrations. Teratology 44: 65-75, 1991.
33. Svenson, K. L. G., T. Pollare, H. Lithell, and R. Hallgren. Impaired glucose handling in active rhuematoid arthritis: relationship to peripheral insulin resistance. Metabolism 37: 125-130, 1988.
34. Tesch, G. H., C. J. Handley, H. J. Cornell, and A. C. Herington. Effects of free and bound insulin-like growth factors on proteoglycan metabolism in articular cartilage explants. J. Orthop. Res. 10: 14-22, 1992.
35. Werner, H., M. Woloschak, M. Adamo, Z. Shen-Orr, C. T. Roberts, Jr., and D. LeRoith. Developmental regulation of the rat insulin-like growth factor I receptor gene. Proc. Natl. Acad Sci. USA 86: 7451-7455, 1989.