-
1
-
-
0003511663
-
-
Atlanta, GA: American Cancer Society
-
American Cancer Society. 1998. Cancer facts and figures. 1998. Atlanta, GA: American Cancer Society.
-
(1998)
Cancer Facts and Figures
-
-
-
2
-
-
0003452668
-
-
Philadelphia: J.B. Lippincott
-
th ed. Philadelphia: J.B. Lippincott.
-
(1992)
th Ed.
-
-
-
3
-
-
0028109165
-
Comparative analysis of mutations in the p53 gene and K-ras genes in pancreatic cancer
-
Berozzpe G, Schaeffer J, Peinado MA, Real FX, Perucho M. 1994. Comparative analysis of mutations in the p53 gene and K-ras genes in pancreatic cancer. Int J Cancer 58:185-191.
-
(1994)
Int J Cancer
, vol.58
, pp. 185-191
-
-
Berozzpe, G.1
Schaeffer, J.2
Peinado, M.A.3
Real, F.X.4
Perucho, M.5
-
4
-
-
0029125820
-
K-ras mutation and pancreatic adenocarcinoma
-
Caldas C, Kern SE. 1995. K-ras mutation and pancreatic adenocarcinoma. Int J Pancreatol 18:1-6.
-
(1995)
Int J Pancreatol
, vol.18
, pp. 1-6
-
-
Caldas, C.1
Kern, S.E.2
-
5
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16(MTS1) gene in pancreatic adenocarcinoma
-
Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruhan RH, Yeo CJ, Kern SE. 1994. Frequent somatic mutations and homozygous deletions of the p16(MTS1) gene in pancreatic adenocarcinoma. Nat Genet 8:27-32.
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruhan, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
6
-
-
0027404853
-
Detection of point mutations in the p53 gene: Comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroylamine and osmium tetroxide techniques
-
Condie A, Eeles R, Borresen AL, Coles C, Cooper C, Prosser J. 1993. Detection of point mutations in the p53 gene: comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroylamine and osmium tetroxide techniques. Hum Mutat 2:56-66.
-
(1993)
Hum Mutat
, vol.2
, pp. 56-66
-
-
Condie, A.1
Eeles, R.2
Borresen, A.L.3
Coles, C.4
Cooper, C.5
Prosser, J.6
-
7
-
-
0030758293
-
Relationship of family cancer history to the expression of p53, p21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma
-
Dergham ST, Dugan MC, Arlauskas P, Du W, Vaitkevicius VK, Crissman JD, Sarkar FH. 1997. Relationship of family cancer history to the expression of p53, p21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma. Int J Pancreatol 21(3):225-234.
-
(1997)
Int J Pancreatol
, vol.21
, Issue.3
, pp. 225-234
-
-
Dergham, S.T.1
Dugan, M.C.2
Arlauskas, P.3
Du, W.4
Vaitkevicius, V.K.5
Crissman, J.D.6
Sarkar, F.H.7
-
8
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, Butel JS, Bradley A. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356(6366):215-221.
-
(1992)
Nature
, vol.356
, Issue.6366
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery C.A., Jr.5
Butel, J.S.6
Bradley, A.7
-
9
-
-
0028950318
-
Screening for p53 gene mutations in archived tumors of workers exposed to carcinogens: Examples from analysis of bladder tumors
-
Esteve A, Sorlie T, Maertel-Plance G, Hollstein M, Kusters I, Lewalter J, Vineis P, Stephan-Odenthal M, Montesano R. 1995. Screening for p53 gene mutations in archived tumors of workers exposed to carcinogens: examples from analysis of bladder tumors. J Occup Environ Med 37:59-68.
-
(1995)
J Occup Environ Med
, vol.37
, pp. 59-68
-
-
Esteve, A.1
Sorlie, T.2
Maertel-Plance, G.3
Hollstein, M.4
Kusters, I.5
Lewalter, J.6
Vineis, P.7
Stephan-Odenthal, M.8
Montesano, R.9
-
10
-
-
0029851830
-
Pancreatic adenocarcinoma: Epidemiology and genetics
-
Flanders TY, Foulkes WD. 1996. Pancreatic adenocarcinoma: epidemiology and genetics. J Med Genet 33:889-898.
-
(1996)
J Med Genet
, vol.33
, pp. 889-898
-
-
Flanders, T.Y.1
Foulkes, W.D.2
-
11
-
-
0030024411
-
Pancreatic cancer: The potential clinical relevance of alterations in growth factors and their receptors
-
Friess H, Berberat P, Schilling M, Kunz J, Korc M, Buchler MW. 1996. Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. J Mol Med 74:35-42.
-
(1996)
J Mol Med
, vol.74
, pp. 35-42
-
-
Friess, H.1
Berberat, P.2
Schilling, M.3
Kunz, J.4
Korc, M.5
Buchler, M.W.6
-
12
-
-
0031911012
-
Epidemiology of and risk factor for pancreatic cancer
-
Gold EB, Goldin SB. 1998. Epidemiology of and risk factor for pancreatic cancer. Surg Oncol Clin N Am 7(1):67-91.
-
(1998)
Surg Oncol Clin N Am
, vol.7
, Issue.1
, pp. 67-91
-
-
Gold, E.B.1
Goldin, S.B.2
-
13
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC. 1994. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
14
-
-
0027435938
-
The rapid detection of unknown mutations in nucleic acids
-
Grompe M. 1993. The rapid detection of unknown mutations in nucleic acids. Nat Genet 5:111-117.
-
(1993)
Nat Genet
, vol.5
, pp. 111-117
-
-
Grompe, M.1
-
15
-
-
0024333967
-
High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas
-
Grunewald K, Lyons J, Frohlich A, Feichtinger H, Weger RA, Schwab G, Janssen JWG, Bartram CR. 1989. High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas. Int J Cancer 43:1037-1041.
-
(1989)
Int J Cancer
, vol.43
, pp. 1037-1041
-
-
Grunewald, K.1
Lyons, J.2
Frohlich, A.3
Feichtinger, H.4
Weger, R.A.5
Schwab, G.6
Janssen, J.W.G.7
Bartram, C.R.8
-
16
-
-
0031051042
-
p53: From inductive signal to cellular effect
-
Hansen R, Oren M. 1997. p53: from inductive signal to cellular effect. Curr Opin Genet Dev 7:46-51.
-
(1997)
Curr Opin Genet Dev
, vol.7
, pp. 46-51
-
-
Hansen, R.1
Oren, M.2
-
17
-
-
0029976723
-
P53 tumor suppressor gene: At the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment
-
Harris CC. 1996. P53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment. Environ Health Perspect 104:435-439.
-
(1996)
Environ Health Perspect
, vol.104
, pp. 435-439
-
-
Harris, C.C.1
-
19
-
-
0028269061
-
Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas
-
Hoshi T, Imai M, Ogawa K. 1994. Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas. J Surg Oncol 55:84-91.
-
(1994)
J Surg Oncol
, vol.55
, pp. 84-91
-
-
Hoshi, T.1
Imai, M.2
Ogawa, K.3
-
20
-
-
0026500701
-
Ki-ras oncogene activation in preinvasive pancreatic cancer
-
Lemoine NR, Jain S, Hughes C, Staddon S, Maillet B, Hall P, Kloppel G. 1992. Ki-ras oncogene activation in preinvasive pancreatic cancer. Gastroenterology 102:230-236.
-
(1992)
Gastroenterology
, vol.102
, pp. 230-236
-
-
Lemoine, N.R.1
Jain, S.2
Hughes, C.3
Staddon, S.4
Maillet, B.5
Hall, P.6
Kloppel, G.7
-
21
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine AJ. 1997. P53, the cellular gatekeeper for growth and division. Cell 88:323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
22
-
-
0031038579
-
Alterations in the tumor suppressor genes p53, RB, p16/MTS1, and p15/MTS2 in human pancreatic cancer and hepatoma cell lines
-
Kaino M. 1997. Alterations in the tumor suppressor genes p53, RB, p16/MTS1, and p15/MTS2 in human pancreatic cancer and hepatoma cell lines. J Gastroenterol 32:40-46.
-
(1997)
J Gastroenterol
, vol.32
, pp. 40-46
-
-
Kaino, M.1
-
23
-
-
0002428437
-
Pancreatic, non-endocrine tumors
-
Kloppel G, Heitz PU, editors. Edinburgh: Churchill Livingstone
-
Kloppel G. 1984. Pancreatic, non-endocrine tumors. In: Kloppel G, Heitz PU, editors. Pancreatic pathology. Edinburgh: Churchill Livingstone, p 79-113.
-
(1984)
Pancreatic Pathology
, pp. 79-113
-
-
Kloppel, G.1
-
24
-
-
0028807377
-
Ras-related proteins in signal transduction and growth control
-
McCormick F. 1995. Ras-related proteins in signal transduction and growth control. Mol Reprod Dev 42:500-506.
-
(1995)
Mol Reprod Dev
, vol.42
, pp. 500-506
-
-
McCormick, F.1
-
25
-
-
0025306220
-
Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer
-
Nagata Y, Abe M, Motoshima K, Nakayma E, Shiku H. 1990. Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer (in Japanese). Jpn J Cancer Res 81:135-140.
-
(1990)
Jpn J Cancer Res
, vol.81
, pp. 135-140
-
-
Nagata, Y.1
Abe, M.2
Motoshima, K.3
Nakayma, E.4
Shiku, H.5
-
26
-
-
0028268635
-
K-ras and p53 gene mutations in pancreatic cancer: Ductal and nonductal tumors progress through different genetic lesions
-
Pellegata NS, Sessa F, Renault B, Bonato M, Leone BE, Solcia E, Ranzani GN. 1994. K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res 54:1556-1560.
-
(1994)
Cancer Res
, vol.54
, pp. 1556-1560
-
-
Pellegata, N.S.1
Sessa, F.2
Renault, B.3
Bonato, M.4
Leone, B.E.5
Solcia, E.6
Ranzani, G.N.7
-
27
-
-
0030063636
-
Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma
-
Rall CJN, Van YX, Graeme-Cook F, Beauchamp R, Yandell DW, Povoskli SP, Rustgi AK. 1996. Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma. Pancreas 12:10-17.
-
(1996)
Pancreas
, vol.12
, pp. 10-17
-
-
Rall, C.J.N.1
Van, Y.X.2
Graeme-Cook, F.3
Beauchamp, R.4
Yandell, D.W.5
Povoskli, S.P.6
Rustgi, A.K.7
-
28
-
-
0028308492
-
p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
-
Redston MS, Caldas C, Seymour CB, Hruban RH, da Costa L, Yeo CJ, Kern SE. 1994. p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 54:3025-3033.
-
(1994)
Cancer Res
, vol.54
, pp. 3025-3033
-
-
Redston, M.S.1
Caldas, C.2
Seymour, C.B.3
Hruban, R.H.4
Da Costa, L.5
Yeo, C.J.6
Kern, S.E.7
-
29
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
Rozenblum E, Schutte M, Goggins M, Hahn SA, Panzer S, Zahurak M, Goodman SN, Sohn TA, Hruban RH, Yeo CJ, Kern SE. 1997. Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 57:1731-1734.
-
(1997)
Cancer Res
, vol.57
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
Hahn, S.A.4
Panzer, S.5
Zahurak, M.6
Goodman, S.N.7
Sohn, T.A.8
Hruban, R.H.9
Yeo, C.J.10
Kern, S.E.11
-
30
-
-
0026663706
-
Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes
-
Ruggeri B, Zhang S-Y, Caamano J, DiRado M, Flynn SD, Klein-Szanto AJP. 1992. Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes. Oncogene 7:1503-1511.
-
(1992)
Oncogene
, vol.7
, pp. 1503-1511
-
-
Ruggeri, B.1
Zhang, S.-Y.2
Caamano, J.3
DiRado, M.4
Flynn, S.D.5
Klein-Szanto, A.J.P.6
-
31
-
-
0031047115
-
Molecular pathology of primary and metastatic ductal pancreatic lesions: Analyses of mutations and expression of the p53, mdm-2, and p21/WAF-1 genes in sporadic and familial lesions
-
Ruggeri BA, Huang L, Berger D, Chang H, Kjlein-Szanto AJ, Goodrow T, Obara T, Heath CW, Lynch H. 1997. Molecular pathology of primary and metastatic ductal pancreatic lesions: analyses of mutations and expression of the p53, mdm-2, and p21/WAF-1 genes in sporadic and familial lesions. Cancer 79:700-716.
-
(1997)
Cancer
, vol.79
, pp. 700-716
-
-
Ruggeri, B.A.1
Huang, L.2
Berger, D.3
Chang, H.4
Kjlein-Szanto, A.J.5
Goodrow, T.6
Obara, T.7
Heath, C.W.8
Lynch, H.9
-
32
-
-
0004282518
-
-
Cary, NC: SAS Institute
-
th ed. Cary, NC: SAS Institute.
-
(1991)
th Ed.
-
-
-
33
-
-
0027743438
-
Pancreatic adenocarcinomas frequently show p53 gene mutations
-
Scarpa A, Capelli P, Mukai K, Zamboni G, Oda T, Iacona C, Hiohashi S. 1993. Pancreatic adenocarcinomas frequently show p53 gene mutations. Am J Pathol 142:1534-1542.
-
(1993)
Am J Pathol
, vol.142
, pp. 1534-1542
-
-
Scarpa, A.1
Capelli, P.2
Mukai, K.3
Zamboni, G.4
Oda, T.5
Iacona, C.6
Hiohashi, S.7
-
34
-
-
0028211438
-
Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences
-
Scarpa A, Capelli P, Villaneuva A, Zamboni G, Lluis F, Accolla R, Mariuzzi G, Capella G. 1994. Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences. Int J Cancer 57:167-171.
-
(1994)
Int J Cancer
, vol.57
, pp. 167-171
-
-
Scarpa, A.1
Capelli, P.2
Villaneuva, A.3
Zamboni, G.4
Lluis, F.5
Accolla, R.6
Mariuzzi, G.7
Capella, G.8
-
35
-
-
0023735997
-
KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas
-
Smit THBM, Boot AJM, Smits AMM, Fleuren GJ, Cornelisse CJ, Bos JL. 1988. KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas. Nucleic Acids Res 16:7773-7782.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 7773-7782
-
-
Smit, T.H.B.M.1
Boot, A.J.M.2
Smits, A.M.M.3
Fleuren, G.J.4
Cornelisse, C.J.5
Bos, J.L.6
-
36
-
-
0028353711
-
Multifactorial analysis of p53 alterations in human cancer: A review
-
Soussi T, Legros Y, Lubin R, Ory K, Schlichtholz B. 1994. Multifactorial analysis of p53 alterations in human cancer: a review. Int J Cancer 57:1-9.
-
(1994)
Int J Cancer
, vol.57
, pp. 1-9
-
-
Soussi, T.1
Legros, Y.2
Lubin, R.3
Ory, K.4
Schlichtholz, B.5
-
37
-
-
0003757194
-
-
College Station, TX: Stata Corp.
-
th ed. College Station, TX: Stata Corp.
-
(1993)
th Ed.
-
-
-
38
-
-
0030050945
-
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease
-
Tada M, Ohashi M, Shiratori Y, Okudaira T, Komatsu Y, Kawabe T, Yoshida H, Machinami R, Kishi K, Omata M. 1996. Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease. Gastroenterology 100:227-231.
-
(1996)
Gastroenterology
, vol.100
, pp. 227-231
-
-
Tada, M.1
Ohashi, M.2
Shiratori, Y.3
Okudaira, T.4
Komatsu, Y.5
Kawabe, T.6
Yoshida, H.7
Machinami, R.8
Kishi, K.9
Omata, M.10
-
39
-
-
0026647264
-
Evidence for synergistic interactions between ras, myc, and a mutant form of p53 in cellular transformation and tumor dissemination
-
Taylor WR, Eagan SE, Mowat M, Greenberger AH, Wright JA. 1992. Evidence for synergistic interactions between ras, myc, and a mutant form of p53 in cellular transformation and tumor dissemination. Oncogene 7:1383-1390.
-
(1992)
Oncogene
, vol.7
, pp. 1383-1390
-
-
Taylor, W.R.1
Eagan, S.E.2
Mowat, M.3
Greenberger, A.H.4
Wright, J.A.5
-
41
-
-
0030048977
-
P53, Ki-ras, and DNA ploidy in pancreatic adenocarcinomas
-
Weyrer K, Feichtinger H, Haun M, Weiss G, Ofner D, Weger AR, Umlauft F, Grunewald K. 1996. P53, Ki-ras, and DNA ploidy in pancreatic adenocarcinomas. Lab Invest 74:279-289.
-
(1996)
Lab Invest
, vol.74
, pp. 279-289
-
-
Weyrer, K.1
Feichtinger, H.2
Haun, M.3
Weiss, G.4
Ofner, D.5
Weger, A.R.6
Umlauft, F.7
Grunewald, K.8
-
42
-
-
0027502624
-
C-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation
-
Yanagisawa K, Ohtake K, Ohashi K, Hori M, Kitagawa T, Sugano H, Kato Y. 1993. C-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation. Cancer Res 53: 953-956.
-
(1993)
Cancer Res
, vol.53
, pp. 953-956
-
-
Yanagisawa, K.1
Ohtake, K.2
Ohashi, K.3
Hori, M.4
Kitagawa, T.5
Sugano, H.6
Kato, Y.7
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