Modulation of constitutive nitric oxide synthase, bcl-2 and fas expression in cultured human coronary endothelial cells exposed to anoxia- reoxygenation and angiotensin II: Role of AT1 receptor activation

Cardiovascular Research

Volumn 41, Issue 1, 1999, Pages 109-115

  Li, Dayuan ^a   Tomson, Kathleen ^a   Yang, Baichun ^a   Mehta, Paulette ^a   Croker, Byron P ^a   Mehta, Jawahar L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Angiotensin II; Anoxia; Apoptosis; AT1 receptors; Bcl 2; Endothelial cell; Fas; Nitrite oxide synthase; Reoxygenation

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; FAS ANTIGEN; LOSARTAN; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; VASCULAR ENDOTHELIUM;

ANALYSIS OF VARIANCE; ANGIOTENSIN II; ANTIGENS, CD95; ANTIHYPERTENSIVE AGENTS; APOPTOSIS; CELLS, CULTURED; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; HUMANS; LOSARTAN; MYOCARDIAL REPERFUSION INJURY; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANGIOTENSIN; RNA, MESSENGER;

EID: 0032938569     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00196-5     Document Type: Article

References (32)

1. Yang BC, Phillips MI, Ambuehl PEJ, et al. Increase in angiotensin II type 1 receptor expression immediately following ischemia-reperfusion in isolated rat hearts. Circulation 1997;96:922-926.
2. Ertl G. Angiotensin converting enzyme inhibitors and ischemic heart disease. Eur Heart J 1988;9:716-727.
3. Pfeffer M, Braunwald E, Boye L. for the SAVE investigators. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. New Engl J Med 1992;327:669-677.
4. Feolde E, Vigne P, Frelin C. Angiotensin II receptor subtypes and biological responses in the rat heart. J Mol Cell Cardiol 1993;25:1359-1367.
5. Stoll M, Steckelings M, Paul M, et al. The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest 1995;95:651-657.
6. Wildhirt SM, Suzuzki H, Horstman D, et al. Selective modulation of inducible nitric oxide synthase isozyme in myocardial infarction. Circulation 1997;96:1616-1623.
7. Pollman MJ, Yamada T, Horiuchi M, Gibbons GH. Vasoactive substances regulate vascular smooth muscle cell apoptosis: counter-vailing influences of nitric oxide and angiotensin II. Circ Res 1996;79:748-756.
8. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 1994;94:1621-1628.
9. Li DY, Weng S, Yang BC, Mehta JL. Angiotensin II augments anoxia-reoxygenation-mediated apoptosis of cultured human coronary endothelial cells: Modulation by ATI receptor antagonist losartan. Circulation 1997;96(1):1-418.
10. Hockenbery DM, Oltvai N, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241-251.
11. Tanaka M, Hiroshi I, Adachi S, et al. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 1994;75:426-430.
12. Dong C, Wilson JE, Winters GI, McManus BM. Human transplant coronary artery disease: pathological evidence for Fas-mediated apoptotic cytotoxicity in allograft arteriopathy. Lab invest 1996;74:921-931.
13. Cigola E, Kajstura J, Li B, Meggs LG, Anversa P. Angiotensin II activates programmed myocyte cell death in vitro. Exp Cell Res 1997;231:363-371.
14. Leung KH, Chang RS, Lotti VJ, et al. ATI receptors mediate the release of prostaglandins in porcine smooth muscle cells and rat astrocytes. Am J Hypertens 1992;5:648-656.
15. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
16. Garvey EP, Tuttle JV, Covington K, et al. Purification and characterization of the constitutive nitric oxide synthase from human placenta. Arch Biochem Biophys 1994;311:235-241.
17. Chen LY, Mehta P, Mehta JL. Oxidized-LDL decreases L-arginine uptake and nitric oxide synthase protein expression in human platelets: Relevance of the effect of oxidized-LDL on platelet function. Circulation 1996;93:1740-1746.
18. Tanaka M, Ohnishi J, Ozawa Y, et al. Characterization of angiotensin II receptor type 2 during differentiation and apoptosis of rat ovarian cultured granulosa cells. Biochem Biophys Res Commun 1995;207:593-598.
19. Mehta JL, Nichols WW, Donnelly WH, et al. Protection by superoxide dismutase from myocardial dysfunction and attenuation of vasodilator reserve after coronary occlusion and reperfusion in dog. Circ Res 1989;65:1283-1295.
20. Tsao PS, Aoki N, Lefer DJ, et al. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat. Circulation 1990;82:1402-1412.
21. Weyrich AS, Ma X-L, Lefer AM. The role of L-arginine in ameliorating reperfusion injury after myocardial ischemia in the cat. Circulation 1992;86:279-288.
22. Yang BC, Chen LY, Saldeen TGP, Mehta JL. Reperfusion injury in the endotoxin-treated rat heart: reevaluation of the role of nitric oxide. Br J Pharmacol 1997;120:305-311.
23. Liao JK, Zulueta JJ, Yu FS, et al. Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen. J Clin Invest 1995;96:2661-2666.
24. Wright CE, Rees DR, Moncada S. Protective and pathological roles of nitric oxide in endotoxin shock. Cardiovasc Res 1992;26:48-57.
25. Joly GA, Ayres M, Chelly F, Kilbourn RG. Effects of N-methyl-L-arginine, N-nitro-L-arginine and aminoguranidine on constitutive and inducible nitric oxide synthase in rat aorta. Biochem Biophys Res Commun 1994;199:147-154.
26. Saito S, Hirata Y, Emori T, Imai T, Marumo F. Angiotensin II activates endothelial constitutive nitric oxide synthase via AT1 receptors. Hypertension Res 1996;19:201-202.
27. Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. Cell 1994;79:1137-1146.
28. Haendeler J, Zeiher AM, Dimmeler S. Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax. Eur J Pharmacol 1996;317:407-411.
29. Tsai JC, Jain M, Hsieh CM, et al. Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem 1996;271:3667-3670.
30. Kondo S, Yin D, Aoki T, et al. Bcl-2 gene prevents apoptosis of basic fibroblast growth factor-deprived murine aortic endothelial cells. Exp Cell Res 1994;213:428-432.
31. Misao J, Hayakawa Y, Ohno M, et al. Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 1996;94:1506-1512.
32. Pierzchalski P, Reiss K, Cheng W, et al. P53 induces myocyte apoptosis via the activation of the renin-angiotensin system. Exp Cell Res 1997;234:57-65.