Functional and immunogenic characterization of two cloned regions of Streptococcus mutans glucosyltransferase I

Infection and Immunity

Volumn 67, Issue 2, 1999, Pages 810-816

  Jespersgaard, Christina ^a   Hajishengallls, George ^b   Greenway, Terrence E ^a   Smith, Daniel J ^c   Russell, Michael W ^a   Michalek, Suzanne M ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c FORSYTH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICARIES AGENT; GLUCAN; GLUCOSYLTRANSFERASE; IMMUNOGLOBULIN A;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CONTROLLED STUDY; DENTAL CARIES; IMMUNE RESPONSE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; STREPTOCOCCUS MUTANS;

STREPTOCOCCUS MUTANS;

EID: 0032935612     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.2.810-816.1999     Document Type: Article

References (33)

1. Aoki, H., T. Shiroza, M. Hayakawa, S. Sato, and H. K. Kuramitsu. 1986. Cloning of a Streptococcus mutans glucosyltransferase gene coding for insoluble glucan synthesis. Infect. Immun. 53:587-594.
2. Banas, J. A., R. R. B. Russell, and J. J. Feretti. 1990. Sequence analysis of the gene for the glucan-binding protein of Streptococcus mutans Ingbritt. Infect. Immun. 58:667-673.
3. Chia, J.-S., R.-H. Lin, S.-W. Lin, J.-Y. Chen, and C.-S. Yang. 1993. Inhibition of glucosyltransferase activities of Streptococcus mutans by a monoclonal antibody to a subsequence peptide. Infect. Immun. 61:4689-4695.
4. Coligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Stroeber. 1991. Current protocols in immunology, vol. 2. Greene Publishing Associates. Inc./John Wiley & Sons. Inc., New York, N.Y.
5. Devulapalle, K. S., S. D. Goodman, Q. Gao, A. Hemsley, and G. Mooser. 1997. Knowledge-based model of a glucosyltransferase from the oral bacterial group of mutans streptococci. Protein Sci. 6:2489-2493.
6. Gravekamp, C., D. L. Kasper, J. L. Michel, D. E. Kling, V. Carey, and L. C. Madoff. 1997. Immunogenicity and protective efficacy of the alpha C protein of group B streptococci are inversely related to the number of repeats. Infect. Immun. 65:5216-5221.
7. Hajishengallis, G., E. Harokopakis, S. K. Hollingshead, M. W. Russell, and S. M. Michalek. 1996. Construction and oral immunogenicity of a Salmonella typhimurium strain expressing a streptococcal adhesin linked to the A2/B subunits of cholera toxin. Vaccine 14:1545-1548.
8. Hajishengallis, G., T. Koga, and M. W. Russell. 1994. Affinity and specificity of the interactions between Streptococcus mutans antigen I/II and salivary components. J. Dent. Res. 73:1493-1502.
9. Harokopakis, E., G. Hajishengallis, T. E. Greenway, M. W. Russell, and S. M. Michalek. 1997. Mucosal immunogenicity of a recombinant Salmonella typhimurium-cloned heterologous antigen in the absence or presence of coexpressed cholera toxin A2 and B subunits. Infect. Immun. 65:1445-1454.
10. Honda, O., C. Kato, and H. K. Kuramitsu. 1990. Nucleotide sequence of the Streptococcus mutans gtfD gene encoding the glucosyltransferase-S enzyme. J. Gen. Microbiol. 136:2099-2105.
11. Kato, C., and H. K. Kuramitsu. 1990. Carboxyl-terminal deletion analysis of the Streptococcus mutans glucosyltransferase-I enzyme. FEMS Microbiol. Lett. 60:299-302.
12. Kato, C., Y. Nakano, M. Lis, and H. K. Kuramitsu. 1992. Molecular genetic analysis of the catalytic site of Streptococcus mutans glucosyltransferases. Biochem. Biophys. Res. Commun. 189:1184-1188.
13. Kuramitsu, H. K. 1993. Virulence factors of mutans streptococci: role of molecular genetics. Crit. Rev. Oral. Biol. Med. 4:159-176.
14. Laloi, P., C. L. Munro, K. R. Jones, and F. L. Macrina. 1996. Immunologic characteristics of a Streptococcus mutans glucosyltransferase B sucrose-binding site peptide-cholera toxin B-subunit chimeric protein. Infect. Immun. 64:28-36.
15. Loesche, W. J. 1986. Role of Streptococcus mutans in human dental decay. Microbiol. Rev. 50:353-380.
16. MacGregor, E. A., H. M. Jespersen, and B. Svensson. 1996. A circularly permuted α-amylase-type α/β-barrel structure in glucan-synthesizing glucosyltransferases. FEBS Lett. 378:263-266.
17. Manthey, C. L., and S. N. Vogel. 1994. Elimination of trace endotoxin protein from rough chemotype LPS. J. Endotoxin Res. 1:84-91.
18. Mooser, G., S. A. Hefta, R. J. Paxton, J. E. Shively, and T. D. Lee. 1991. Isolation and sequence of an active-site peptide containing a catalytic aspartic acid from two Streptococcus sobrinus alpha-glucosyltransferases. J. Biol. Chem. 266:8916-8922.
19. Mooser, G., and C. Wong. 1988. Isolation of a glucan-binding domain of glucosyltransferase (1,6-α-glucan synthase) from Streptococcus sobrinus. Infect. Immun. 56:880-884.
20. Munro, C., S. M. Michalek, and F. L. Macrina. 1991. Cariogenicity of Streptococcus mutans V403 glucosyltransferase and fructosyltransferase mutants constructed by allelic exchange. Infect. Immun. 59:2316-2323.
21. Russell, R. R., T. Shiroza, H. K. Kuramitsu, and J. J. Ferretti. 1988. Homology of glucosyltransferase gene and protein sequences from Streptococcus sobrinus and Streptococcus mutans. J. Dent. Res. 67:543-547.
22. Shiroza, T., S. Ueda, and H. K. Kuramitsu. 1987. Sequence analysis of the gtfB gene from Streptococcus mutans. J. Bacteriol. 169:4263-4270.
23. Smith, D. J., B. Shoushtari, R. L. Heschel, W. F. King, and M. A. Taubman. 1997. Immunogenicity and protective immunity induced by synthetic peptides associated with a catalytic subdomain of mutans group streptococcal glucosyltransferase. Infect. Immun. 65:4424-4430.
24. Smith, D. J., M. A. Taubman, and J. L. Ebersole. 1985. Salivary IgA antibody to glucosyltransferase in man. Clin. Exp. Immunol. 61:416-424.
25. Smith, D. J., M. A. Taubman, C. F. Holmberg, J. Eastcott, W. F. King, and P. Ali-Salaam. 1993. Antigenicity and immunogenicity of a synthetic peptide derived from a glucan-binding domain of mutans streptococcal glucosyltransferase. Infect. Immun. 61:2899-2905.
26. Smith, D. J., M. A. Taubman, W. F. King, S. Eida, J. R. Powell, and J. Eastcott. 1994. Immunological characteristics of a synthetic peptide associated with a catalytic domain of mutans streptococcal glucosyltransferase. Infect. Immun. 62:5470-5476.
27. Tabor, S., and C. C. Richardson. 1985 A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes. Proc. Natl. Acad. Sci. USA 82:1074-1078.
28. Taubman, M. A., C. J. Holmberg, and D. J. Smith. 1995. Immunization of rats with synthetic peptide constructs from the glucan-binding or catalytic region of mutans streptococcal glucosyltransferase protects against dental caries. Infect. Immun. 63:3088-3093.
29. Tomita, Y., X. Zhu, K. Ochiai, Y. Namiki, T. Okada, T. Ikemi, and K. Fukushima. 1996. Evaluation of three individual glucosyltransferases produced by Streptococcus mutans using monoclonal antibodies. FEMS Microbiol. Lett. 145:427-432.
30. Isumori, H., T. Minami, and H. K. Kuramitsu. 1997 Identification of essential amino acids in the Streptococcus mutans glucosyltransferases. J. Bacteriol. 179:3391-3396.
31. Ueda, S., T. Shiroza, and H. K. Kuramitsu. 1988. Sequence analysis of the gtfC gene from Streptococcus mutans GS-5. Gene 69:101-109.
32. Vamashita, Y., W. H. Bowen, R. A. Burne, and H. K. Kuramitsu. 1993. Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect. Immun. 61:3811-3817.
33. Yu, H., Y. Nakano, Y. Yamashita, T. Ohio, and T. Koga. 1997 Effects of antibodies against cell surface protein antigen PAc-glucosyltransferase fusion proteins on glucan synthesis and cell adhesion of Streptococcus mutans. Infect. Immun. 65:2292-2298.