Effects of antibodies against cell surface protein antigen PAc- glucosyltransferase fusion proteins on glucan synthesis and cell adhesion of Streptococcus mutans

Infection and Immunity

Volumn 65, Issue 6, 1997, Pages 2292-2298

  Yu, Hao ^a   Nakano, Yoshio ^a   Yamashita, Yoshihisa ^a   Oho, Takahiko ^a   Koga, Andtoshihiko ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; GLUCAN; GLUCOSYLTRANSFERASE; HYBRID PROTEIN;

ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERIAL COLONIZATION; CELL ADHESION; IMMUNIZATION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS MUTANS;

EID: 0031001179     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.6.2292-2298.1997     Document Type: Article

References (37)

1. Amann, E., B. Ochs, and K.-J. Abel. 1988. Tightly regulated tac promoter vectors useful for the expression of unfused and fused proteins in Escherichia coli. Gene 69:301-315.
2. Aoki, H., T. Shiroza, M. Hayakawa, S. Sato, and H. K. Kuramitsu. 1986. Cloning of a Streptococcus mutans glucosyltransferase gene coding for insoluble glucan synthesis. Infect. Immun. 53:587-594.
3. Bowen, W. H., K. Schilling, E. Giertsen, S. Pearson, S. F. Lee, A. Bleiweis, and D. Beeman. 1991. Role of a cell surface-associated protein in adherence and dental caries. Infect. Immun. 59:4606-4609.
4. Brady, L. J., D. A. Piacentini, P. J. Crowley, P. C. F. Oyston, and A. S. Bleiweis. 1992. Differentiation of salivary agglutinin-mediated adherence and aggregation of mutans streptococci by use of monoclonal antibodies against the major surface adhesin P1. Infect. Immun. 60:1008-1017.
5. Chia, J.-S., R.-H. Lin, S.-W. Lin, J.-Y. Chen, and C.-S. Yang. 1943. Inhibition of glucosyltransferase activities of Streptococcus mutans by a monoclonal antibody to a subsequence peptide. Infect. Immun. 61:4689-4695.
6. Cope, P. A., and G. Mooser. 1993. Antibodies against active-site peptides common to glucosyltransferases of mutans streptococci. Infect. Immun. 61:4814-1817.
7. Crowley, P. J., L. J. Brady, D. A. Piacentini, and A. S. Bleiweis. 1993. Identification of a salivary agglutinin-binding domain within cell surface adhesin P1 at Streptococcus mutans. Infect. Immun. 61:1547-1552.
8. Dertzbaugh, M. T., and C. O. Elson. 1993. Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines. Infect. Immun. 61:48-55.
9. Gangloff, S., R. M'Zoughi, E. Lett, M. Schöller, J. Baer, A. Pini, J. Ogier, and J.-P. Klein. 1992. Epitope mapping of Streptococcus mutans SR protein and human IgG cross-reactive determinants, by using recombinant proteins and synthetic peptides. J. Immunol. 148:3249-3255.
10. Giffard, P. M., and N. A. Jacques. 1994. Definition of a fundamental repeating unit in streptococcal glucosyltransferase glucan-binding regions and related sequences. J. Dent. Res. 73:1133-1141.
11. Hujishengallis, G., S. K. Hollingshead, T. Koga, and M. W. Russell. 1995. Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B subunits. J. Immunol. 154:4322-4332.
12. Hajishengallis, G., T. Koga, and M. W. Russell. 1994. Affinity and specificity of the interactions between Streptococcus mutans antigen I/II and salivary components. J. Dent. Res. 73:1493-1502.
13. Hamada, S., T. Horikoshi, T. Minami, N. Okahashi, and T. Koga. 1989. Purification and characterization of cell-associated glucosyltransferase synthesizing water-insoluble glucan from serotype c Streptococcus mutans. J. Gen. Microbiol. 135:335-344.
14. Hanada, N., and H. K. Kuramitsu. 1989. Isolation and characterization of the Streptococcus mutans gtfD gene, coding for primer-dependent soluble glucan synthesis. Infect. Immun. 57:2079-2085.
15. Kelly, C., P. Evans, L. Bergmeier, S. F. Lee, A. Progulske-Fox, A. C. Harris, A. Aitken, A. S. Bleiweis, and T. Lehner. 1989. Sequence analysis of the cloned streptococcal cell surface antigen I/II. FEES Lett. 258:127-132.
16. Kelly, C. G., S. Todryk, H. L. Kendal, G. H. Munro, and T. Lehner. 1995. T-cell, adhesion, and B-cell epitopes of the cell surface Streptococcus mutans protein antigen I/II. Infect. Immun. 63:3649-3658.
17. Koga, T., H. Asakawa, N. Okahashi, and S. Hamada, 1986. Sucrose-dependent cell adherence and cariogenicity of serotype c Streptococcus mutans. J. Gen. Microbiol. 132:2873-2883.
18. Koga, T., N. Okahashi, I. Takahashi, T. Kanamoto, H. Asakawa, and M. Iwaki. 1990. Surface hydrophobicity, adherence, and aggregation of cell surface protein antigen mutants of Streptococcus mutans serotype c. Infect. Immun. 58:289-296.
19. Koga, T., Y. Yamashita, Y. Nukaiio, M. Kawasaki, T. Oho, H. Yu, M. Natai, and N. Okahashi. 1995. Surface proteins of Streptococcus mutans. Dev. Biol. Stand. 85:363-369.
20. Kuramitsu, H. K., M. Smorawinska, Y. J. Nakano, A. Shimamura, and M. Lis. 1995. Analysis of gluean synthesis by Streptococcus mutans. Dev. Biol. Stand. 85:303-307.
21. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
22. Laloi, P., C. L. Munro, K. K. Jones, and F. L. Macrina. 1996. Immunologic characteristics of a Streptococcus mutans glucosyltransferase B sucrose-binding site peptide-cholera toxin B-subunit chimeric protein. Infect. Immun. 64:28-36.
23. Lee, S. F., A. Progulske-Fox, G. W. Erdos, D. A. Piacentini, G. Y. Ayakawa, P. J. Crowley, and A. S. Bleiweis, 1989. Construction and characterization of isogenic mutants of Streptococcus mutans deficient in major surface protein antigen P1 (I/II). Infect. Immun. 57:3306-3313.
24. Lehner, T., J. K.-C. Ma, G. Munro, P. Walker, A. Childerstone, S. Todryk, H. Kendal, and C. G. Kelly. 1994. T-cell and B-cell epitope mapping and construction of peptide vaccines, p. 274-292. In R. Genco, S. Hamada, T. Lehner, J. McGhee, and S. Mergenhagen (ed.), Molecular pathogenesis of periodontal disease. ASM Press, Washington, D.C.
25. Moisset, A., N. Schatz, Y. Lepoivre, S. Amadio, D. Wachsmann, M. Schöller, and J.-P. Klein. 1994. Conservation of salivary glycoprotein-interacting and human immunoglobulin G-cross-reactive domains of antigen I/II in oral streptococci. Infect. Immun. 62:184-193.
26. Munro, G. H., P. Evans, S. Todryk, P. Bukett, C. G. Kelly, and T. Lehner. 1993. A protein fragment of streptococcal cell surface antigen I/II which prevents adhesion of Streptococcus mutans. Infect. Immun. 61:4590-4598.
27. Nakai, M., N. Okahashi, H. Ohta, and T. Koga. 1993. Saliva-binding region of Streptococcus mutans surface protein antigen. Infect. Immun. 61:4344-4349.
28. Okahashi, N., C. Sasakawa, M. Yoshikawa, S. Hamada, and T. Koga. 1989. Molecular characterization of a surface protein antigen gene from serotype c Streptococcus mutans, implicated in dental caries. Mol. Microbiol. 3:673-678.
29. Russell, M. W. 1992. Immunization against dental caries. Curr. Opin. Dent. 2:72-80.
30. Russell, R. R. B. 1994. The application of molecular genetics to the microbiology of dental caries. Caries Res. 28:69-82.
31. Schachtele, C. F., S. K. Harlander, J. W. Bracke, L. C. Ostrum, J.-A. B. Maltais, and R. J. Billings. 1978. Streptococcus mutans dextransucrase: stimulation by phospholipids from human sera and oral fluids. Infect. Immun. 22:714-720.
32. Shiroza, T., and H. K. Kuramitsu. 1993. Construction of a model secretion system for oral streptococci. Infect. Immun. 61:3745-3755.
33. Shiroza, T., S. Ueda, and H. K. Kuramitsu. 1987. Sequence analysis of the gtfB gene from Streptococcus mutans. J. Bacteriol. 169:4263-4270.
34. Smith, D. J., M. A. Taubman, W. F. King, S. Eida, J. R. Powell, and J. Eastcott. 1994. Immunological characteristics of a synthetic peptide associated with a catalytic domain of mutans streptococcal glucosyltransferase. Infect. Immun. 62:5470-5476.
35. Taubman, M. A., C. J. Holmberg, and D. J. Smith. 1995. Immunization of rats with synthetic peptide constructs from the glucan-binding or catalytic region of mutans streptococcal glucosyltransferase protects against dental caries. Infect. Immun. 63:3088-3093.
36. Von Eichel-Strelber, C., M. Sauerborn, and H. K. Kuramitsu. 1992. Evidence for a modular structure of the homologous repetitive C-terminal carbohydrate-binding sites of Clostridium difficile toxins and Streptococcus mutans glucosyltransferases. J. Bacteriol. 174:6707-6710.
37. Yamashita, Y., W. H. Bowen, R. A. Burne, and H. K. Kuramitsu. 1993. Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect. Immun. 61:3811-3817.