Mechanism of verapamil block of a neuronal delayed rectifier K channel: Active form of the blocker and location of its binding domain

British Journal of Pharmacology

Volumn 126, Issue 8, 1999, Pages 1699-1706

  Catacuzzeno, L ^a   Trequattrini, C ^a   Petris, A ^a   Franciolini, F ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

Author keywords

D890; Delayed rectifier K channel; DRG neurons; Mechanism of block; Patch clamp; TEA; Verapamil

Indexed keywords

D 890; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM CHANNEL; VERAPAMIL;

ANIMAL CELL; ARTICLE; BINDING SITE; CHICKEN; CONTROLLED STUDY; CYTOPLASM; DRUG MECHANISM; DRUG PROTEIN BINDING; ELECTRIC POTENTIAL; EMBRYO; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN DOMAIN; SPINAL GANGLION;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BIOTRANSFORMATION; CALCIUM CHANNEL BLOCKERS; CHICK EMBRYO; ELECTROPHYSIOLOGY; GALLOPAMIL; GANGLIA, SPINAL; KINETICS; NEURONS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; TETRAETHYLAMMONIUM; VERAPAMIL;

EID: 0032933822     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702477     Document Type: Article

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