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Volumn 24, Issue 3, 1999, Pages 261-268

Lamifiban. Platelet antiaggregatory, fibrinogen gpIIb/IIIa receptor antagonist

Author keywords

[No Author keywords available]

Indexed keywords

3 [[4 [4 [AMINO(ETHOXYCARBONYLIMINO)METHYL]PHENYL] 2 THIAZOLYL](1 ETHOXYCARBONYLMETHYL 4 PIPERIDINYL)AMINO]PROPIONIC ACID ETHYL ESTER; 3 ACETOXY 5 [2 (DIMETHYLAMINO)ETHYL] 2,3 DIHYDRO 8 METHYL 2 (4 METHYLPHENYL) 1,5 BENZOTHIAZEPIN 4(5H) ONE MALEATE; 4 (4 AMIDINOBENZOYLGLYCYL) 3 METHOXYCARBONYLMETHYL 2 OXO 1 PIPERAZINEACETIC ACID; 4 (4 AMIDINOPHENOXY)BUTYRYLASPARTYLVALINE; 4 [[3 [4 [IMINO[(METHOXYCARBONYL)AMINO]METHYL]PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL] 1 PIPERAZINEACETIC ACID ETHYL ESTER; ABCIXIMAB; ANTITHROMBOCYTIC AGENT; CT 50352; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; FRADAFIBAN; GR 233548; LAMIFIBAN; LEFRADAFIBAN; LOTRAFIBAN; RWJ 533078; S 1197; SDZ GPI 562; SIBRAFIBAN; T 250; TIROFIBAN; UNCLASSIFIED DRUG; YM 028; YM 337;

EID: 0032929006     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.1999.024.03.527582     Document Type: Review
Times cited : (3)

References (52)
  • 5
    • 0345173583 scopus 로고    scopus 로고
    • Spotlight update: Fibrinogen (gpIIb/IIIa) receptor antagonists
    • Spotlight update: Fibrinogen (gpIIb/IIIa) receptor antagonists. Prous Science Daily Essentials March 1, 1999.
    • (1999) Prous Science Daily Essentials March 1
  • 6
    • 0344311159 scopus 로고
    • TRAP-induced ex vivo platelet aggregation might be a useful method to predict anti-thrombotic efficacy
    • Abst 1122
    • Steiner, B., Jones, C.R., van Heiningen, P.N.M., Jonkman, J.H.G., Carroll, R.C., Kouns, W.C. TRAP-induced ex vivo platelet aggregation might be a useful method to predict anti-thrombotic efficacy. Blood 1993, 10(Suppl. 1): Abst 1122.
    • (1993) Blood , vol.10 , Issue.SUPPL. 1
    • Steiner, B.1    Jones, C.R.2    Van Heiningen, P.N.M.3    Jonkman, J.H.G.4    Carroll, R.C.5    Kouns, W.C.6
  • 8
    • 0345605665 scopus 로고
    • Identification of a peptidomimetic inhibitor with minimal effects on the conformation of GPIIb-IIIa
    • Abst 650
    • Kouns, W.C., Weller, T., Hadvary, P., Jennings, L.K., Steiner, B. Identification of a peptidomimetic inhibitor with minimal effects on the conformation of GPIIb-IIIa. Blood 1992, 80(10, Suppl. 1): Abst 650.
    • (1992) Blood , vol.80 , Issue.10 SUPPL. 1
    • Kouns, W.C.1    Weller, T.2    Hadvary, P.3    Jennings, L.K.4    Steiner, B.5
  • 9
    • 0001410543 scopus 로고
    • Five independent neo-epitopes on GPIIb-IIIa are differentially exposed by two potent peptidomimetic platelet inhibitors
    • Abst 860
    • Steiner, B., Häring, P., Jennings, L., Kouns, W.C. Five independent neo-epitopes on GPIIb-IIIa are differentially exposed by two potent peptidomimetic platelet inhibitors. Thromb Haemost 1993, 69(6): Abst 860.
    • (1993) Thromb Haemost , vol.69 , Issue.6
    • Steiner, B.1    Häring, P.2    Jennings, L.3    Kouns, W.C.4
  • 10
    • 0344743466 scopus 로고
    • GP IIb-IIIa antagonists like lamifiban (Ro 44-9883) that do not induce conformational changes are potent inhibitors of platelet adhesion to fibrinogen
    • Abst 1594
    • Satoh, T., Kouns, W.C., Steiner, B. GP IIb-IIIa antagonists like lamifiban (Ro 44-9883) that do not induce conformational changes are potent inhibitors of platelet adhesion to fibrinogen. Thromb Haemost 1995, 73(6): Abst 1594.
    • (1995) Thromb Haemost , vol.73 , Issue.6
    • Satoh, T.1    Kouns, W.C.2    Steiner, B.3
  • 11
    • 0013653351 scopus 로고
    • Functional relevance of LIBS expression in the response to platelet glycoprotein antagonists in vivo
    • Abst 1591
    • Murphy, N., Jennings, L., Pratico, D., Doyle, C., Fitzgerald, D.J. Functional relevance of LIBS expression in the response to platelet glycoprotein antagonists in vivo. Thromb Haemost 1995, 73(6): Abst 1591.
    • (1995) Thromb Haemost , vol.73 , Issue.6
    • Murphy, N.1    Jennings, L.2    Pratico, D.3    Doyle, C.4    Fitzgerald, D.J.5
  • 12
    • 0032411217 scopus 로고    scopus 로고
    • Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo
    • Murphy, N.P., Pratico, D., Fitzgerald, D.J. Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. J Pharmacol Exp Ther 1998, 286: 945-51.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 945-951
    • Murphy, N.P.1    Pratico, D.2    Fitzgerald, D.J.3
  • 13
    • 0028849289 scopus 로고
    • Role of collagen-adherent platelets in mediating fibrin formation in flowing whole blood
    • Kirchhofer, D., Tschopp, T.B., Steiner, B., Baumgartner, H.R. Role of collagen-adherent platelets in mediating fibrin formation in flowing whole blood. Blood 1995, 86: 3815-22.
    • (1995) Blood , vol.86 , pp. 3815-3822
    • Kirchhofer, D.1    Tschopp, T.B.2    Steiner, B.3    Baumgartner, H.R.4
  • 14
    • 0344743463 scopus 로고
    • Antithrombotic effect of a new inhibitor of platelet glycoprotein IIb-IIIa, Ro 44-9883, in guinea-pig thrombosis model
    • Abst P-97
    • Takiguchi, Y., Wada, K., Asai, F., Nishiyama, H., Nakashima, M. Antithrombotic effect of a new inhibitor of platelet glycoprotein IIb-IIIa, Ro 44-9883, in guinea-pig thrombosis model. Jpn J Pharmacol 1993, 61 (Suppl. 1): Abst P-97.
    • (1993) Jpn J Pharmacol , vol.61 , Issue.SUPPL. 1
    • Takiguchi, Y.1    Wada, K.2    Asai, F.3    Nishiyama, H.4    Nakashima, M.5
  • 15
    • 0027526992 scopus 로고
    • Ro 44-9883, a new nonpeptidic GPIIb-GPIIIa antagonist prevents platelet loss in a guinea pig model of extracorporeal circulation
    • Carteaux, J.P., Steiner, B., Roux, S. Ro 44-9883, a new nonpeptidic GPIIb-GPIIIa antagonist prevents platelet loss in a guinea pig model of extracorporeal circulation. Thromb Haemost 1993, 70: 817-21.
    • (1993) Thromb Haemost , vol.70 , pp. 817-821
    • Carteaux, J.P.1    Steiner, B.2    Roux, S.3
  • 16
    • 0027515415 scopus 로고
    • Ro 44-9883, a new nonpeptide glycoprotein IIb/IIIa antagonist, prevents platelet loss during experimental cardiopulmonary bypass
    • Carteaux, J.P., Roux, S., Kuhn, H., Tschopp, T., Colombo, V., Hadvéry, P. Ro 44-9883, a new nonpeptide glycoprotein IIb/IIIa antagonist, prevents platelet loss during experimental cardiopulmonary bypass. J Thorac Cardiovasc Surg 1993, 106: 834-41.
    • (1993) J Thorac Cardiovasc Surg , vol.106 , pp. 834-841
    • Carteaux, J.P.1    Roux, S.2    Kuhn, H.3    Tschopp, T.4    Colombo, V.5    Hadvéry, P.6
  • 17
    • 0344743462 scopus 로고    scopus 로고
    • GPIIb/IIIa receptor blockade at reperfusion reduces infarct size in the dog
    • Abst 4163
    • Dagenais, P., Libersan, D., Merhi, Y., Rousseau, G., Latour, J.-G. GPIIb/IIIa receptor blockade at reperfusion reduces infarct size in the dog. Circulation 1997, 96(8, Suppl.): Abst 4163.
    • (1997) Circulation , vol.96 , Issue.8 SUPPL.
    • Dagenais, P.1    Libersan, D.2    Merhi, Y.3    Rousseau, G.4    Latour, J.-G.5
  • 19
    • 0345605662 scopus 로고
    • Interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor
    • (Aug 27-31, Seattle) Abst 268
    • Lave, T., Saner, A., Coassolo, P., Schmitt-Hoffmann, A.H., Chou, R.C. Interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor. 4th Int ISSX Meet (Aug 27-31, Seattle) 1995, Abst 268.
    • (1995) 4th Int ISSX Meet
    • Lave, T.1    Saner, A.2    Coassolo, P.3    Schmitt-Hoffmann, A.H.4    Chou, R.C.5
  • 20
    • 0030036409 scopus 로고    scopus 로고
    • Animal pharmacokinetics and interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor
    • Lave, T., Saner, A., Coassolo, P., Brandt, R., Schmitt-Hoffmann, A.H., Chou, R.C. Animal pharmacokinetics and interspecies scaling from animals to man of lamifiban, a new platelet aggregation inhibitor. J Pharm Pharmacol 1996, 48: 573-7.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 573-577
    • Lave, T.1    Saner, A.2    Coassolo, P.3    Brandt, R.4    Schmitt-Hoffmann, A.H.5    Chou, R.C.6
  • 22
    • 0031860510 scopus 로고    scopus 로고
    • Increased potency and decreased elimination of lamifiban, a GPIIb-IIIa antagonist, in patients with severe renal dysfunction
    • Lehne, G., Nordal, K.P., Midtvedt, K., Goggin, T., Brosstad, F. Increased potency and decreased elimination of lamifiban, a GPIIb-IIIa antagonist, in patients with severe renal dysfunction. Thromb Haemost 1998, 79: 1119-25.
    • (1998) Thromb Haemost , vol.79 , pp. 1119-1125
    • Lehne, G.1    Nordal, K.P.2    Midtvedt, K.3    Goggin, T.4    Brosstad, F.5
  • 23
    • 0000647588 scopus 로고
    • Flow cytometry as a quantitative measure of the antiplatelet activity of a glycoprotein IIb-IIIa inhibitor
    • Abst 3558
    • Anderson, D.R., Zayed, E., Embree, J., Theroux, P., Steiner, B. Flow cytometry as a quantitative measure of the antiplatelet activity of a glycoprotein IIb-IIIa inhibitor. Blood 1995, 86(10, Suppl. 1): Abst 3558.
    • (1995) Blood , vol.86 , Issue.10 SUPPL. 1
    • Anderson, D.R.1    Zayed, E.2    Embree, J.3    Theroux, P.4    Steiner, B.5
  • 24
    • 0345173577 scopus 로고
    • A rapid flow cytometric method to monitor plasma concentrations of GP IIb-IIIa antagonists in the clinic
    • Abst 1269
    • Kouns, W.C., Weller, T., Steiner, B. A rapid flow cytometric method to monitor plasma concentrations of GP IIb-IIIa antagonists in the clinic. Blood 1994, 84(10, Suppl. 1): Abst 1269.
    • (1994) Blood , vol.84 , Issue.10 SUPPL. 1
    • Kouns, W.C.1    Weller, T.2    Steiner, B.3
  • 25
  • 26
    • 0345553953 scopus 로고    scopus 로고
    • Platelet-membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study
    • Théroux, P., Kouz, S., Roy, L. et al. Platelet-membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina. The Canadian Lamifiban Study. Circulation 1996, 94: 899-905.
    • (1996) Circulation , vol.94 , pp. 899-905
    • Théroux, P.1    Kouz, S.2    Roy, L.3
  • 27
    • 0032560628 scopus 로고    scopus 로고
    • International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina
    • The PARAGON Investigators. International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina. Circulation 1998, 97: 2386-95.
    • (1998) Circulation , vol.97 , pp. 2386-2395
  • 28
    • 0344853945 scopus 로고    scopus 로고
    • Combining IIb/IIIa inhibition and heparin for acute coronary syndromes: Evidence of a gradient for bleeding hazard from the PARAGON randomized factorially designed trial
    • Abst 1033-38
    • Harrington, R.A., Newby, L.K., Moliterno, D.J. et al. Combining IIb/IIIa inhibition and heparin for acute coronary syndromes: Evidence of a gradient for bleeding hazard from the PARAGON randomized factorially designed trial. J Am Coll Cardiol 1997, 29(2, Suppl. A): Abst 1033-38.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.2 SUPPL. A
    • Harrington, R.A.1    Newby, L.K.2    Moliterno, D.J.3
  • 29
    • 0008946601 scopus 로고    scopus 로고
    • Late diverging event curves for survival following IIb/IIIa antagonism in patients with unstable angina: PARAGON study 1-year follow-up
    • Abst 854-6
    • Moliterno, D.J., Harrington, R.A., Newby, K.L., Armstrong, P.W., Van de Werf, F., White, H.D., Califf, R.M., Topol, E.J. Late diverging event curves for survival following IIb/IIIa antagonism in patients with unstable angina: PARAGON study 1-year follow-up. J Am Coll Cardiol 1998, 31(2, Suppl. A): Abst 854-6.
    • (1998) J Am Coll Cardiol , vol.31 , Issue.2 SUPPL. A
    • Moliterno, D.J.1    Harrington, R.A.2    Newby, K.L.3    Armstrong, P.W.4    Van De Werf, F.5    White, H.D.6    Califf, R.M.7    Topol, E.J.8
  • 30
    • 0000973487 scopus 로고    scopus 로고
    • Pronounced reduction in long-term ischemic events with platelet IIb/IIIa antagonism among diabetics with unstable angina: PARAGON 6-month results
    • Abst 2646
    • Moliterno, D.J., Harrington, R.A., Newby, K., Bhapkar, M., Emanuelsson, H., Armstrong, P.W., Topol, E.J. Pronounced reduction in long-term ischemic events with platelet IIb/IIIa antagonism among diabetics with unstable angina: PARAGON 6-month results. Circulation 1997, 96(8, Suppl.): Abst 2646.
    • (1997) Circulation , vol.96 , Issue.8 SUPPL.
    • Moliterno, D.J.1    Harrington, R.A.2    Newby, K.3    Bhapkar, M.4    Emanuelsson, H.5    Armstrong, P.W.6    Topol, E.J.7
  • 32
    • 0000396490 scopus 로고    scopus 로고
    • Plasma concentration of lamifiban and glycoprotein IIb-IIIa receptor occupancy best predict clinical outcome in patients with unstable angina: Results from PARAGON A
    • Abst 3420
    • Steiner, B., Hofer, U., Wittke, B., Topol, E.J., Califf, R.M., Harrington, R.A., Armstrong, P.W., Van de Werf, F., Moliterno, D.J. Plasma concentration of lamifiban and glycoprotein IIb-IIIa receptor occupancy best predict clinical outcome in patients with unstable angina: Results from PARAGON A. Eur Heart J 1998, 19(Suppl.): Abst 3420.
    • (1998) Eur Heart J , vol.19 , Issue.SUPPL.
    • Steiner, B.1    Hofer, U.2    Wittke, B.3    Topol, E.J.4    Califf, R.M.5    Harrington, R.A.6    Armstrong, P.W.7    Van De Werf, F.8    Moliterno, D.J.9
  • 33
    • 0001094450 scopus 로고    scopus 로고
    • Plasma level of lamifiban and platelet receptor occupancy best predict clinical outcome in patients with unstable angina: Results from PARAGON A
    • Abst 2955
    • Steiner, B., Hofer, U., Wittke, B., Harrington, R.A., Bhapkar, M.V., Armstrong, P.W., Moliterno, D.J. Plasma level of lamifiban and platelet receptor occupancy best predict clinical outcome in patients with unstable angina: Results from PARAGON A. Circulation 1998, 98(17, Suppl.): Abst 2955.
    • (1998) Circulation , vol.98 , Issue.17 SUPPL.
    • Steiner, B.1    Hofer, U.2    Wittke, B.3    Harrington, R.A.4    Bhapkar, M.V.5    Armstrong, P.W.6    Moliterno, D.J.7
  • 34
    • 0001145269 scopus 로고
    • Randomized, placebo-controlled study of lamifiban with thrombolytic therapy for the treatment of acute myocardial infarction: Rationale and design for the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) study
    • Moliterno, D.J., Harrington, R.A., Califf, R.M., Rapold, H.J., Topol, E.J. Randomized, placebo-controlled study of lamifiban with thrombolytic therapy for the treatment of acute myocardial infarction: Rationale and design for the Platelet Aggregation Receptor Antagonist Dose Investigation and Reperfusion Gain in Myocardial Infarction (PARADIGM) study. J Thromb Thrombolysis 1995, 2: 165-9.
    • (1995) J Thromb Thrombolysis , vol.2 , pp. 165-169
    • Moliterno, D.J.1    Harrington, R.A.2    Califf, R.M.3    Rapold, H.J.4    Topol, E.J.5
  • 35
    • 0031809073 scopus 로고    scopus 로고
    • New antiplatelet agents for acute coronary syndromes
    • Ferguson, J.J., Lau, T.K. New antiplatelet agents for acute coronary syndromes. Am Heart J 1998, 135(5, Part 2): S194-200.
    • (1998) Am Heart J , vol.135 , Issue.5 PART 2
    • Ferguson, J.J.1    Lau, T.K.2
  • 36
    • 0001144438 scopus 로고    scopus 로고
    • Thrombocytopenia with GP IIb/IIIa inhibitors: A meta-analysis
    • Abst 837-5
    • Giugliano, R.P., Hyatt, R.R. Jr. Thrombocytopenia with GP IIb/IIIa inhibitors: A meta-analysis. J Am Coll Cardiol 1998, 31(2, Suppl. A): Abst 837-5.
    • (1998) J Am Coll Cardiol , vol.31 , Issue.2 SUPPL. A
    • Giugliano, R.P.1    Hyatt R.R., Jr.2
  • 37
    • 0344311154 scopus 로고    scopus 로고
    • F. Hoffman-La Roche AG Company Communication Nov 18
    • Lamifiban development status. F. Hoffman-La Roche AG Company Communication Nov 18, 1998.
    • (1998) Lamifiban Development Status
  • 38
    • 13044261825 scopus 로고
    • Overdosing of potent GP IIb-IIIa antagonists differentially prolongs the bleeding time in guinea pigs
    • Abst 66
    • Roux, S., Bunting, S., Kouns, C., Steiner, B. Overdosing of potent GP IIb-IIIa antagonists differentially prolongs the bleeding time in guinea pigs. Thromb Haemost 1993, 69(6): Abst 66.
    • (1993) Thromb Haemost , vol.69 , Issue.6
    • Roux, S.1    Bunting, S.2    Kouns, C.3    Steiner, B.4
  • 39
    • 0000888542 scopus 로고    scopus 로고
    • Delaying and preventing ischemic events in patients with acute coronary syndromes using the platelet glycoprotein IIb/IIIa inhibitor lamifiban
    • Abst 1033-31
    • Harrington, R.A., Moliterno, D.J., Van de Werf, F. et al. Delaying and preventing ischemic events in patients with acute coronary syndromes using the platelet glycoprotein IIb/IIIa inhibitor lamifiban. J Am Coll Cardiol 1997, 29(2, Suppl. A): Abst 1033-31.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.2 SUPPL. A
    • Harrington, R.A.1    Moliterno, D.J.2    Van De Werf, F.3
  • 40
    • 0344311153 scopus 로고    scopus 로고
    • The paradigm for anti-platelet effect on continuous 12-lead ST-segment recovery in acute MI
    • Abst 738-3
    • Krucoff, M.W., Harrington, R.A., Moliterno, D.J. et al. The paradigm for anti-platelet effect on continuous 12-lead ST-segment recovery in acute MI. J Am Coll Cardiol 1997, 29(2, Suppl. A): Abst 738-3.
    • (1997) J Am Coll Cardiol , vol.29 , Issue.2 SUPPL. A
    • Krucoff, M.W.1    Harrington, R.A.2    Moliterno, D.J.3
  • 41
    • 0007441581 scopus 로고    scopus 로고
    • Amplification of clinical benefit at six months with the glycoprotein IIb/IIIa inhibitor lamifiban in patients with non ST segment elevation acute coronary syndromes
    • Abst 2645
    • Harrington, R.A., Moliterno, D.J., Newby, K. et al. Amplification of clinical benefit at six months with the glycoprotein IIb/IIIa inhibitor lamifiban in patients with non ST segment elevation acute coronary syndromes. Circulation 1997, 96(8, Suppl.): Abst 2645.
    • (1997) Circulation , vol.96 , Issue.8 SUPPL.
    • Harrington, R.A.1    Moliterno, D.J.2    Newby, K.3
  • 42
    • 0009505012 scopus 로고
    • A randomized double-blind controlled trial with the non-peptide platelet GP IIb/IIIa antagonist Ro 44-9883 in unstable angina
    • Abst 1243
    • Théroux, P., Kouz, S., Knudtson, M.L., Kells, C., Nasmith, J., Roy, L., Dalle Ave, S., Steiner, B., Xiao, Z., Rapold, H.J. A randomized double-blind controlled trial with the non-peptide platelet GP IIb/IIIa antagonist Ro 44-9883 in unstable angina. Circulation 1994, 90(4, Part 2): Abst 1243.
    • (1994) Circulation , vol.90 , Issue.4 PART 2
    • Théroux, P.1    Kouz, S.2    Knudtson, M.L.3    Kells, C.4    Nasmith, J.5    Roy, L.6    Dalle Ave, S.7    Steiner, B.8    Xiao, Z.9    Rapold, H.J.10
  • 43
    • 0345173572 scopus 로고    scopus 로고
    • A randomized trial of potent platelet IIb/IIIa antagonism, heparin, or both in patients with unstable angina: The PARAGON study
    • Abst 3234
    • PARAGON Investigators. A randomized trial of potent platelet IIb/IIIa antagonism, heparin, or both in patients with unstable angina: The PARAGON study. Circulation 1996, 94(8, Suppl.): Abst 3234.
    • (1996) Circulation , vol.94 , Issue.8 SUPPL.
  • 44
    • 0000440352 scopus 로고    scopus 로고
    • More complete and stable reperfusion with platelet IIb/IIIa antagonism plus thrombolysis for AMI: The PARADIGM trial
    • Abst 3232
    • Moliterno, D.J., Harrington, R.A., Krucoff, M.W. et al. More complete and stable reperfusion with platelet IIb/IIIa antagonism plus thrombolysis for AMI: The PARADIGM trial. Circulation 1996, 94(8, Suppl.): Abst 3232.
    • (1996) Circulation , vol.94 , Issue.8 SUPPL.
    • Moliterno, D.J.1    Harrington, R.A.2    Krucoff, M.W.3
  • 45
    • 0007441503 scopus 로고    scopus 로고
    • Meta-analysis of platelet GP IIb/IIIa antagonist randomized clinical trials in ischemic heart disease: Consistent, durable, salutary effects
    • Abst 2652
    • Moliterno, D.J., Topol, E.J. Meta-analysis of platelet GP IIb/IIIa antagonist randomized clinical trials in ischemic heart disease: Consistent, durable, salutary effects. Circulation 1997, 96(8, Suppl.): Abst 2652.
    • (1997) Circulation , vol.96 , Issue.8 SUPPL.
    • Moliterno, D.J.1    Topol, E.J.2
  • 46
    • 0344311151 scopus 로고    scopus 로고
    • Tight control of aPTT in acute coronary syndrome patients using an automated strategy for bedside heparin adjustment: Results from the PARAGON A trial
    • Abst 4200
    • Newby, K., Harrington, R.A., Bhapkar, M., Granger, C.B., Rames, A., Moliterno, D.J. Tight control of aPTT in acute coronary syndrome patients using an automated strategy for bedside heparin adjustment: Results from the PARAGON A trial. Circulation 1997, 96(8, Suppl.): Abst 4200.
    • (1997) Circulation , vol.96 , Issue.8 SUPPL.
    • Newby, K.1    Harrington, R.A.2    Bhapkar, M.3    Granger, C.B.4    Rames, A.5    Moliterno, D.J.6
  • 48
    • 0344311150 scopus 로고
    • The effects of Ro 43-5054 and Ro 44-9883, peptidomimetic inhibitors of the GPIIb-IIIa fibrinogen binding site, on platelet stimulus-response coupling
    • Abst 868
    • Carroll, R.C., Steiner, B., Kouns, W.C. The effects of Ro 43-5054 and Ro 44-9883, peptidomimetic inhibitors of the GPIIb-IIIa fibrinogen binding site, on platelet stimulus-response coupling. Thromb Haemost 1993, 69(6): Abst 868.
    • (1993) Thromb Haemost , vol.69 , Issue.6
    • Carroll, R.C.1    Steiner, B.2    Kouns, W.C.3
  • 49
    • 8544262806 scopus 로고
    • Inhibition of fibrinogen binding to platelets by MK-852 and Ro 44-9883. Two low molecular weight gpIIb/IIIa antagonists
    • Abst 375
    • Larsson, A., Lindahl, T.L. Inhibition of fibrinogen binding to platelets by MK-852 and Ro 44-9883. Two low molecular weight gpIIb/IIIa antagonists. Thromb Haemost 1995, 73(6): Abst 375.
    • (1995) Thromb Haemost , vol.73 , Issue.6
    • Larsson, A.1    Lindahl, T.L.2
  • 50
    • 0031939116 scopus 로고    scopus 로고
    • An overview of the results of clinical trials with glycoprotein IIb/IIIa inhibitors
    • Adgey, A.A.J. An overview of the results of clinical trials with glycoprotein IIb/IIIa inhibitors. Eur Heart J 1998,19(Suppl. D): D10-21.
    • (1998) Eur Heart J , vol.19 , Issue.SUPPL. D
    • Adgey, A.A.J.1
  • 51
    • 0031959918 scopus 로고    scopus 로고
    • An overview of the results of clinical trials with glycoprotein IIb/IIIa inhibitors
    • Adgey, A.A.J. An overview of the results of clinical trials with glycoprotein IIb/IIIa inhibitors. Am Heart J 1998, 135: 843-55.
    • (1998) Am Heart J , vol.135 , pp. 843-855
    • Adgey, A.A.J.1
  • 52
    • 0345605654 scopus 로고
    • Synthetic non-peptide GP IIb-IIIa antagonists for the treatment and prevention of arterial thrombosis
    • Abst S24.3
    • Steiner, B., Kouns, W.C., Roux, S., Weller, T., Rapold, H.J., Jones, R.C. Synthetic non-peptide GP IIb-IIIa antagonists for the treatment and prevention of arterial thrombosis. Can J Physiol Pharmacol 1994, 72(Suppl. 1): Abst S24.3.
    • (1994) Can J Physiol Pharmacol , vol.72 , Issue.SUPPL. 1
    • Steiner, B.1    Kouns, W.C.2    Roux, S.3    Weller, T.4    Rapold, H.J.5    Jones, R.C.6


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