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Volumn 135, Issue 4, 1998, Pages

An overview of the results of clinical trials with glycoprotein IIb/IIIa inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; ALTEPLASE; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; FIBRINOLYTIC AGENT; HEPARIN; HEPTAPEPTIDE; LAMIFIBAN; PLACEBO; TIROFIBAN; UNCLASSIFIED DRUG;

EID: 0031959918     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(98)70297-2     Document Type: Article
Times cited : (42)

References (40)
  • 1
    • 2242477091 scopus 로고
    • Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
    • The EPIC Investigators Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty N Engl J Med 330 1994 956 961
    • (1994) N Engl J Med , vol.330 , pp. 956-961
    • The EPIC Investigators1
  • 2
    • 0028345255 scopus 로고
    • Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months
    • EJ Topol RM Califf HF Weisman Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: results at six months Lancet 343 1994 881 886
    • (1994) Lancet , vol.343 , pp. 881-886
    • Topol, EJ1    Califf, RM2    Weisman, HF3
  • 3
    • 8544284052 scopus 로고    scopus 로고
    • Long-term protection from myocardial ischemic events in a randomized trial of brief integrin β3 blockade with percutaneous coronary intervention
    • 3 blockade with percutaneous coronary intervention JAMA 278 1997 479 484
    • (1997) JAMA , vol.278 , pp. 479-484
    • Topol, EJ1    Ferguson, JJ2    Weisman, HF3
  • 4
    • 0030738122 scopus 로고    scopus 로고
    • Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization
    • AM Lincoff RM Califf KM Anderson Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization J Am Coll Cardiol 30 1997 149 156
    • (1997) J Am Coll Cardiol , vol.30 , pp. 149-156
    • Lincoff, AM1    Califf, RM2    Anderson, KM3
  • 5
    • 0030004098 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa receptor blockade by a chimeric monoclonal antibody (abciximab) on acute and six-month outcomes after percutaneous transluminal coronary angioplasty for acute myocardial infarction
    • J Lefkovits RJ Ivanhoe RM Califf Effects of platelet glycoprotein IIb/IIIa receptor blockade by a chimeric monoclonal antibody (abciximab) on acute and six-month outcomes after percutaneous transluminal coronary angioplasty for acute myocardial infarction Am J Cardiol 77 1996 1045 1051
    • (1996) Am J Cardiol , vol.77 , pp. 1045-1051
    • Lefkovits, J1    Ivanhoe, RJ2    Califf, RM3
  • 6
    • 0030273574 scopus 로고    scopus 로고
    • Increased risk of non-Q wave myocardial infarction after directional atherectomy is platelet dependent: evidence from the EPIC Trial
    • J Lefkovits JC Blankenship KM Anderson Increased risk of non-Q wave myocardial infarction after directional atherectomy is platelet dependent: evidence from the EPIC Trial J Am Coll Cardiol 28 1996 849 855
    • (1996) J Am Coll Cardiol , vol.28 , pp. 849-855
    • Lefkovits, J1    Blankenship, JC2    Anderson, KM3
  • 7
    • 0344141599 scopus 로고
    • Can conjunctive platelet glycoprotein IIb/IIIa receptor blockade improve outcomes of coronary interventions for restenotic lesions [abstract]?
    • J Lefkovits GL Stoner KM Anderson HF Weisman EJ Topol Can conjunctive platelet glycoprotein IIb/IIIa receptor blockade improve outcomes of coronary interventions for restenotic lesions [abstract]? Circulation 92 suppl I 1995 I607
    • (1995) Circulation , vol.92 , Issue.suppl I , pp. I607
    • Lefkovits, J1    Stoner, GL2    Anderson, KM3    Weisman, HF4    Topol, EJ5
  • 8
    • 0001258838 scopus 로고
    • Platelet glycoprotein IIb/IIIa monoclonal antibody (c7E3) reduces distal embolization during percutaneous intervention of saphenous vein grafts [abstract]
    • RM Challapalli MJ Eisenberg K Sigmon J Lemberger Platelet glycoprotein IIb/IIIa monoclonal antibody (c7E3) reduces distal embolization during percutaneous intervention of saphenous vein grafts [abstract] Circulation 92 suppl I 1995 I607
    • (1995) Circulation , vol.92 , Issue.suppl I , pp. I607
    • Challapalli, RM1    Eisenberg, MJ2    Sigmon, K3    Lemberger, J4
  • 9
    • 0343122956 scopus 로고
    • Special considerations for diabetics receiving platelet IIb/IIIa antagonists during coronary interventions: results from the EPIC Trial [abstract]
    • DJ Moliterno RM Califf K Anderson HF Weisman EJ Topol EPIC Study Investigators Special considerations for diabetics receiving platelet IIb/IIIa antagonists during coronary interventions: results from the EPIC Trial [abstract] J Am Coll Cardiol 25 1995 155A 156A
    • (1995) J Am Coll Cardiol , vol.25 , pp. 155A-156A
    • Moliterno, DJ1    Califf, RM2    Anderson, K3    Weisman, HF4    Topol, EJ5    EPIC Study Investigators6
  • 10
    • 9544243719 scopus 로고    scopus 로고
    • Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty
    • DB Mark JD Talley EJ Topol Economic assessment of platelet glycoprotein IIb/IIIa inhibition for prevention of ischemic complications of high-risk coronary angioplasty Circulation 94 1996 629 635
    • (1996) Circulation , vol.94 , pp. 629-635
    • Mark, DB1    Talley, JD2    Topol, EJ3
  • 11
    • 0002571590 scopus 로고    scopus 로고
    • The economics of IIb/IIIa therapy
    • WB Hillegass The economics of IIb/IIIa therapy J Invas Cardiol 8 suppl B 1996 30B 33B
    • (1996) J Invas Cardiol , vol.8 , Issue.suppl B , pp. 30B-33B
    • Hillegass, WB1
  • 12
    • 0031970904 scopus 로고    scopus 로고
    • Costs and effects in acute coronary syndrome: the case of ReoPro in high risk PTCA patients
    • BA Van Hout L Bowman DJ Zelinger ML Simoons Costs and effects in acute coronary syndrome: the case of ReoPro in high risk PTCA patients Am Heart J 135 1998 S98 S106
    • (1998) Am Heart J , vol.135 , pp. S98-S106
    • Van Hout, BA1    Bowman, L2    Zelinger, DJ3    Simoons, ML4
  • 13
    • 0031966339 scopus 로고    scopus 로고
    • Abciximab therapy in percutaneous intervention: economic issues in the United States
    • AK Goklaney JD Murphy WB Hillegass Jr Abciximab therapy in percutaneous intervention: economic issues in the United States Am Heart J 135 1998 S90 S97
    • (1998) Am Heart J , vol.135 , pp. S90-S97
    • Goklaney, AK1    Murphy, JD2    Hillegass, WB3
  • 14
    • 0029030141 scopus 로고
    • Bleeding complications with the chimeric antibody to platelet glycoprotein IIb/IIIa integrin in patients undergoing percutaneous coronary intervention
    • FV Aguirre EJ Topol JJ Ferguson Bleeding complications with the chimeric antibody to platelet glycoprotein IIb/IIIa integrin in patients undergoing percutaneous coronary intervention Circulation 91 1995 2882 2890
    • (1995) Circulation , vol.91 , pp. 2882-2890
    • Aguirre, FV1    Topol, EJ2    Ferguson, JJ3
  • 15
    • 1842369101 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization
    • The EPILOG Investigators Platelet glycoprotein IIb/IIIa receptor blockade and low-dose heparin during percutaneous coronary revascularization N Engl J Med 336 1997 1689 1696
    • (1997) N Engl J Med , vol.336 , pp. 1689-1696
    • The EPILOG Investigators1
  • 16
    • 8044222756 scopus 로고    scopus 로고
    • Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization
    • AM Lincoff JE Tcheng RM Califf Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization Am J Cardiol 79 1997 286 291
    • (1997) Am J Cardiol , vol.79 , pp. 286-291
    • Lincoff, AM1    Tcheng, JE2    Califf, RM3
  • 17
    • 0023864355 scopus 로고
    • Thrombolysis in Myocardial Infarction (TIMI) trial—phase I: hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase
    • AK Rao C Pratt A Berke Thrombolysis in Myocardial Infarction (TIMI) trial—phase I: hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase J Am Coll Cardiol 11 1988 1 11
    • (1988) J Am Coll Cardiol , vol.11 , pp. 1-11
    • Rao, AK1    Pratt, C2    Berke, A3
  • 18
    • 85119795755 scopus 로고    scopus 로고
    • Abciximab (c7E3) reduces death and myocardial infarction but not target vessel revascularization in diabetics undergoing percutaneous transluminal coronary angioplasty: the EPILOG experience [abstract]
    • NS Kleiman AM Lincoff DP Miller Abciximab (c7E3) reduces death and myocardial infarction but not target vessel revascularization in diabetics undergoing percutaneous transluminal coronary angioplasty: the EPILOG experience [abstract] Eur Heart J 18 suppl 1997 13
    • (1997) Eur Heart J , vol.18 , Issue.suppl , pp. 13
    • Kleiman, NS1    Lincoff, AM2    Miller, DP3
  • 19
    • 0000596748 scopus 로고    scopus 로고
    • Economic assessment of platelet glycoprotein IIb/IIIa receptor blockade during coronary intervention in the EPILOG Trial [abstract]
    • AM Lincoff DB Mark RM Califf Economic assessment of platelet glycoprotein IIb/IIIa receptor blockade during coronary intervention in the EPILOG Trial [abstract] J Am Coll Cardiol 29 1997 240A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 240A
    • Lincoff, AM1    Mark, DB2    Califf, RM3
  • 20
    • 23444458293 scopus 로고
    • Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina
    • ML Simoons MJ de Boer MJBM van den Brand Randomized trial of a GPIIb/IIIa platelet receptor blocker in refractory unstable angina Circulation 89 1994 596 603
    • (1994) Circulation , vol.89 , pp. 596-603
    • Simoons, ML1    de Boer, MJ2    van den Brand, MJBM3
  • 21
    • 0030918995 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE Study
    • The CAPTURE Investigators Randomised placebo-controlled trial of abciximab before and during coronary intervention in refractory unstable angina: the CAPTURE Study Lancet 349 1997 1429 1435
    • (1997) Lancet , vol.349 , pp. 1429-1435
    • The CAPTURE Investigators1
  • 22
    • 0342777621 scopus 로고    scopus 로고
    • Reduction of recurrent ischemia with abciximab during continuous ECG-ischemia monitoring in patients with unstable angina refractory to standard treatment (CAPTURE) [abstract]
    • P Klootwijk S Meij R Melkert ML Simoons Reduction of recurrent ischemia with abciximab during continuous ECG-ischemia monitoring in patients with unstable angina refractory to standard treatment (CAPTURE) [abstract] J Am Coll Cardiol 29 1997 367A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 367A
    • Klootwijk, P1    Meij, S2    Melkert, R3    Simoons, ML4
  • 23
    • 0027194452 scopus 로고
    • Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy: results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 pilot study
    • NS Kleiman EM Ohman RM Califf Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy: results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 pilot study J Am Coll Cardiol 22 1993 381 389
    • (1993) J Am Coll Cardiol , vol.22 , pp. 381-389
    • Kleiman, NS1    Ohman, EM2    Califf, RM3
  • 24
    • 0030919511 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II
    • The IMPACT-II Investigators Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II Lancet 349 1997 1422 1428
    • (1997) Lancet , vol.349 , pp. 1422-1428
    • The IMPACT-II Investigators1
  • 25
    • 16944362255 scopus 로고    scopus 로고
    • Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction: results of a randomized, placebo-controlled, dose-ranging trial
    • EM Ohman NS Kleiman G Gacioch Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction: results of a randomized, placebo-controlled, dose-ranging trial Circulation 95 1997 846 854
    • (1997) Circulation , vol.95 , pp. 846-854
    • Ohman, EM1    Kleiman, NS2    Gacioch, G3
  • 26
    • 85119804600 scopus 로고    scopus 로고
    • Califf RM. PURSUIT. Presented at the 70th Scientific Sessions of the American Heart Association; November 9-12, 1997, Orlando, Fla.
  • 27
    • 0345553953 scopus 로고    scopus 로고
    • Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina: the Canadian Lamifiban Study
    • P Théroux S Kouz L Roy Platelet membrane receptor glycoprotein IIb/IIIa antagonism in unstable angina: the Canadian Lamifiban Study Circulation 94 1996 899 905
    • (1996) Circulation , vol.94 , pp. 899-905
    • Théroux, P1    Kouz, S2    Roy, L3
  • 28
    • 0002776983 scopus 로고    scopus 로고
    • Relationship of outcomes to treatment with lamifiban in patients undergoing PTCA: analysis of PARAGON A [abstract]
    • JH Alexander LK Newby DJ Moliterno Relationship of outcomes to treatment with lamifiban in patients undergoing PTCA: analysis of PARAGON A [abstract] J Am Coll Cardiol 29 1997 409A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 409A
    • Alexander, JH1    Newby, LK2    Moliterno, DJ3
  • 29
    • 0000888542 scopus 로고    scopus 로고
    • Delaying and preventing ischemic events in patients with acute coronary syndromes using the platelet glycoprotein IIb/IIIa inhibitor lamifiban [abstract]
    • RA Harrington DJ Moliterno F Van de Werf Delaying and preventing ischemic events in patients with acute coronary syndromes using the platelet glycoprotein IIb/IIIa inhibitor lamifiban [abstract] J Am Coll Cardiol 29 1997 409A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 409A
    • Harrington, RA1    Moliterno, DJ2    Van de Werf, F3
  • 30
    • 0030857049 scopus 로고    scopus 로고
    • Clinical trials with glycoprotein IIb/IIIa receptor antagonists in acute coronary syndromes
    • F Van de Werf Clinical trials with glycoprotein IIb/IIIa receptor antagonists in acute coronary syndromes Thromb Haemost 78 1997 210 213
    • (1997) Thromb Haemost , vol.78 , pp. 210-213
    • Van de Werf, F1
  • 31
    • 85119809906 scopus 로고    scopus 로고
    • Van de Werf F. PARAGON. Presented at the 19th Congress of the European Society of Cardiology; August 24-28, 1997, Stockholm, Sweden.
  • 32
    • 85119804220 scopus 로고    scopus 로고
    • Harrington RA. PARADIGM. Presented at the 69th Scientific Sessions of the American heart Association, November 10-13, 1996, New Orleans, La.
  • 33
    • 4244044287 scopus 로고    scopus 로고
    • Analysis of hospital costs and outcomes in RESTORE [abstract]
    • RESTORE Economic Study Group Analysis of hospital costs and outcomes in RESTORE [abstract] J Am Coll Cardiol 29 1997 395A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 395A
    • RESTORE Economic Study Group1
  • 34
    • 0343376106 scopus 로고    scopus 로고
    • Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty
    • The RESTORE Investigators Effects of platelet glycoprotein IIb/IIIa blockade with tirofiban on adverse cardiac events in patients with unstable angina or acute myocardial infarction undergoing coronary angioplasty Circulation 96 1997 1445 1453
    • (1997) Circulation , vol.96 , pp. 1445-1453
    • The RESTORE Investigators1
  • 35
    • 85119787535 scopus 로고    scopus 로고
    • White HD. PRISM. Presented at the 46th Annual Scientific Session of the American College of Cardiology; March 16-19, 1997, Anaheim, Calif.
  • 36
    • 85119806767 scopus 로고    scopus 로고
    • Théroux P. PRISM-PLUS. Presented at the 46th Annual Scientific Session of the American College of Cardiology; March 16-19, 1997, Anaheim, Calif.
  • 37
    • 0030738111 scopus 로고    scopus 로고
    • Results from late breaking clinical trials sessions at ACC '97
    • RJ. Cody Results from late breaking clinical trials sessions at ACC '97 J Am Coll Cardiol 30 1997 1 7
    • (1997) J Am Coll Cardiol , vol.30 , pp. 1-7
    • Cody, RJ.1
  • 38
    • 0000728218 scopus 로고    scopus 로고
    • Use of abciximab (ReoPro) is not associated with an increase in the risk of stroke: overview of three randomized trials [abstract]
    • J Deckers RM Califf EJ Topol AM Lincoff JE Tcheng ML Simoons Use of abciximab (ReoPro) is not associated with an increase in the risk of stroke: overview of three randomized trials [abstract] J Am Coll Cardiol 29 1997 241A
    • (1997) J Am Coll Cardiol , vol.29 , pp. 241A
    • Deckers, J1    Califf, RM2    Topol, EJ3    Lincoff, AM4    Tcheng, JE5    Simoons, ML6
  • 39
    • 0344101457 scopus 로고    scopus 로고
    • A platelet glycoprotein IIb/IIIa inhibitor (ReoPro) as an adjunctive therapy in elective stenting: initial experience with safety and efficacy [abstract]
    • LA Guzman PL Whitlow EJ Topol SG Ellis A platelet glycoprotein IIb/IIIa inhibitor (ReoPro) as an adjunctive therapy in elective stenting: initial experience with safety and efficacy [abstract] J Invas Cardiol 8 1996 46
    • (1996) J Invas Cardiol , vol.8 , pp. 46
    • Guzman, LA1    Whitlow, PL2    Topol, EJ3    Ellis, SG4
  • 40
    • 8244262792 scopus 로고    scopus 로고
    • ReoPro plus stenting: pushing the envelope of clinical applications for stents [abstract]
    • RA Yaryura S Simek J Benrey ReoPro plus stenting: pushing the envelope of clinical applications for stents [abstract] J Inv Cardiol 8 1996 67
    • (1996) J Inv Cardiol , vol.8 , pp. 67
    • Yaryura, RA1    Simek, S2    Benrey, J3


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