Tumor gene therapy made easy: Allogeneic major histocompatibility complex in the C6 rat glioma model

Human Gene Therapy

Volumn 10, Issue 1, 1999, Pages 95-101

  Beutler, Andreas S ^a,b   Banck, Michaela S ^a,b   Wedekind, Dirk ^c   Hedrich, Hans J ^c  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE THERAPY; GENETIC TRANSDUCTION; GLIOMA; HAPLOTYPE; MOUSE; NONHUMAN; RAT; TUMOR IMMUNITY; TUMOR REGRESSION;

ANIMALS; BRAIN NEOPLASMS; FLOW CYTOMETRY; GENE EXPRESSION; GENE THERAPY; GLIOBLASTOMA; HERPESVIRUS 4, HUMAN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MICE; MICE, NUDE; NUCLEAR PROTEINS; RATS; SEROLOGIC TESTS; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 0032927487     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950019228     Document Type: Article

References (35)

1. BENDA, P., LIGHTBODY, J., SATO, G., LEVINE, L., and SWEET, W. (1968). Differentiated rat glial cell strain in tissue culture. Science 161, 370-371.
2. BENDA, P., SOMEDA, K., MESSER. J., and SWEET, W.H. (1971). Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture. J. Neurosurg. 34, 310-323.
3. BENDER, K., BALOGH, P., BERTRAND, M.F., DEN BIEMAN, M., VON DEIMLING, O., EGHTESSADI, S., GUTMAN, G.A., HEDRICH, H.J., HUNT, V., KLUGE, R., MATSUMOTO, K., MORALEJO, D.H., NAGEL, M., PORTAL, A., PROKOP, C.-M., SEIBERT, R.T., and VAN ZUTPHEN, L.F.M. (1994). Genetic characterization of inbred strains of the rat (Rattus norvegicus). J. Exp. Anim. Sci. 36, 151-165.
4. CARSON, W.E., III, JAKOWATZ, J.G., YAMAMOTO, R., FITZGERALD, T., GUPTA, S., VAYUVEGULA, B., LUCCI, J.A., BECKMAN, M.T., DULKANCHAINUN, S., GRANGER, G.A., and JEFFES, W.B., III (1991). Rat mitogen-stimulated lymphokine-activated T killer cells: Production and effects of C6 glioma cells in vitro and in vivo in the brain of Wistar rats. J Immunother. 10, 131-140.
5. CHIOCCA, E.A., BOVIATSIS, E.J., FILIPEK, P.A., BREAKIFIELD, X.O., and KENNEDY, D.N. (1993). Gene therapy for gliomas using virus vectors. Neuroimmunol Res. 6, 23-32.
6. DAVID-WATINE, B., ISRAEL, A., and KOURILSKY, P. (1990). The regulation and expression of MHC class I genes. Immunol. Today 11, 286-292.
7. DRUCKREY, H., IVANKOVIC, S., and PREUSSMANN R. (1965). Selektive Erzeugung maligner Tumoren im Gehirn and Ruckenmark von Ratten durch N-methyl-N-nitrosoharnstoff. [Selective induction of malignant tumors in the brain and spinal cord of rats by N-methyl-N-nitrosourea.] Z. Krebsforsch. 66, 389-408.
8. FEARON, E.R., ITAYA, T., HUNT, B., VOGELSTEIN, B., and FROST, P. (1988). Induction in a murine tumor of immunogenic tumor variants by transfection with a foreign gene. Cancer Res. 48, 2975-2980.
9. GOBIN, S.J., PEIJNENBURG, A., KEIJSERS, V., and VAN DEN ELSEN, P.J. (1997). Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: The ISRE-mediated route and a novel pathway involving CIITA. Immunity 6, 601-611.
10. GUNTHER, E. (1990). In Generic Monitoring of Inbred Strains of Rats. H.J. Hedrich, ed. (Gustaf Fischer Verlag, Stuttgart/New York), pp. 79-88.
11. JOHNSON, T.R., TROJAN, J., ANTHONY, D.D., RUDIN, S.D., TYKOCINSKI, M.L., ILAN, J., and ILAN, J. (1994). Gene therapy of rat brain glioblastoma by an episome-based transcriptional casette expressing antisense IGF-I cDNA. Indian J. Biochem. Biophys. 31, 1-13.
12. KAPLITT, G., TJUVAJEV, J.G., LEIB, D.A., BERK, J., PETTIGREW, K.D., POSNER, J.B., PFAFF, D.W., RABKIN, S.D., and BLASBERG, R.G. (1994). Mutant herpes simplex virus induced regression of tumors growing in immunocompetent rats. J Neuro-Oncol. 19, 137-147.
13. KO, L., KOESTNER, A., and WECHSLER, W. (1980a). Morphological characterization of nitrosourea-induced glioma cell lines and clones. Acta Neuropathol. 51, 23-31.
14. KO, L., KOESTNER, A., and WECHSLER, W. (1980b). Characterization of cell cycle and biological parameters of transplantation glioma cell line clones. Acta Neuropathol. 51, 107-111.
15. KONDZIOLKA, D., LUNSFORD, L.D., CLAASSEN, M.D., PANDALAI, S., MAITZ, A.H., and FLICKINGER, J.C. (1992). Radiobiology of radiosurgery. II. The rat C6 glioma model. Neurosurgery 31, 280-288.
16. LITTLE, C.C., and TYZZER, E.F. (1924). Genetic studies of transplantation of two adenocarcinomas. J. Exp. Zool. 41, 93.
17. LIU, S.K.M., JAKOWATZ, J.G., POLLACK, R.B., CERALDI, C., YAMAMOTO, R., DETT, C., LOPEZ, F., CAMACHO, C., CARSON, W.E., SENTOVICH, S.M., JACQUES, D., and GRANGER, G.A. (1991). Effects of intracarotid and intravenous infusion of human TNF and LT on established intracerebral rat gliomas. Lymphokine Cytokine Res. 10(3), 189-194.
18. MACH, B., STEIMLE, V., MARTINEZ-SORIA, E., and REITH, W. (1996). Regulation of MHC class II genes: Lessons from a disease. Annu. Rev. Immunol. 14, 301-331.
19. MARON, A., GUSTIN, T., LE ROUX, A., MOTTET, I., DEDIEU, J.-F., BRION, J.-F., DEMEURE, R., PERRICAUDET, M., and OCTAVE, J.-N. (1996). Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: Long-term follow-up by magnetic resonance imaging. Gene Ther. 3, 315-322.
20. MARTIN, B.K., CHIN, K.C., OLSEN, J.C., SKINNER, C.A., DEY, A., OZATO, K., and TING, J.P. (1997). Induction of MHC class I expression by the MHC class II transactivator CIITA. Immunity 6, 591-600.
21. NAGANO, N., SASAKI, H., AOYAGI, M., and HIRAKAWA, K. (1993). Invasion of experimental rat brain tumor: Early morphological changes following microinjection of C6 glioma cells. Acta Neurophathol. 86, 117-125.
22. PLATE, K.H., BREIER, G., MILLAUER, B., ULLRICH, A., and RISAU, W. ( 1993). Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis. Cancer Res. 53, 5822-5827.
23. RESNICOFF, M., SELL, C., RUBINI, M., COPPOLA, D., AMBROSE, D., BASERGA, R., and RUBIN, R. (1994). Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-I (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. Cancer Res. 54, 2218-2222.
24. RESNICOFF, M., BURGAUD, J.-L., ROTMAN, H.L., ABRAHAM, D., and BASERGA, R. (1995). Correlation between apoptosis, tumorigenesis, and levels of insulin-like growth factor I receptor. Cancer Res. 55, 3739-3741.
25. RESNICOFF, M., LI, W., BASAK, S., HERLYN, D., BASERGA, R., and RUBIN, R. (1996). Inhibition of rat C6 glioblastoma tumor growth be expression of insulin-like growth factor I antisense mRNA. Cancer Immunol. Immunother. 42, 64-68.
26. RICHARDSON, U.I., TASHJIAN, A.H., JR., and LEVINE, L. (1969). Establishment of a clonal strain of hepatoma cells which secrete albumin. J. Cell Biol. 40, 236-247.
27. RUBINSTEIN, L.J. (1977). Correlation of animal brain tumor models with human neuro-oncology. Natl. Cancer Inst. Monogr. 46, 43-49.
28. SAMPSON, J.H., ARCHER, J.G., and BIGNER, D.D. (1999). The use of experimental models in neuro-oncological research. In Neurosurgery: The Scientific Basis of Clinical Practice, 3rd Ed. (Blackwell Science, Oxford, UK) Chapter 41. (In press.)
29. STEIMLE, V., OTTEN, L.A., ZUFFEREY, M., and MACH, B. (1993). Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75, 135-146.
30. SUGIURA, K., and STOCK, C.C. (1955). Studies in a tumor spectrum. III. The effect of phosphoramides on the growth of a variety of mouse and rat tumors. Cancer Res. 15, 38-51.
31. TROJAN, J., BLOSSEY, B.K., JOHNSON, T.R., RUDIN, S.D., TYKOCINSKI, M., ILAN, J., and ILAN, J. (1992). Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I. Proc. Natl. Acad. Sci. U.S.A. 89, 4874-4878.
32. TROJAN, J., JOHNSON, T.R., RUDIN, S.D., ILAN, J., TYKOCINSKI, M., and ILAN, J. (1993). Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA. Science 259, 94-97.
33. TROJAN, J., DUC, H.T., UPEGUI-GONZALEZ, L.C., HOR, F., GUO, Y., ANTHONY, D., and ILAN, J. (1996). Presence of MHC-I and B-7 molecules in rat and human glioma cells expressing antisense IGF-I mRNA. Neurosci. Lett. 212, 9-12.
34. TZENG, J.-J., BARTH, R.F., CLENDENON, N.R., and GORDON, W.A. (1990). Adoptive immunotherapy of a rat glioma using lymphokine-activated killer cells. Cancer Res. 50, 4338-4343.
35. WEDEKIND, D., PROKOP, C.M., BRUNSBERG, U., HOLMDAHL, R., and HEDRICH, H.J. (1997). Identification and differentiation of transcribed major histocompatibility complex class II RT1.B alpha and RT1.B beta alleles from laboratory rats. Transplant. Proc. 29, 1668-1669.