Prospective follow-up and pulmonary functions from a placebo-controlled randomized trial of ribavirin therapy in respiratory syncytial virus bronchiolitis

Archives of Pediatrics and Adolescent Medicine

Volumn 153, Issue 5, 1999, Pages 469-474

  Rodriguez, William J ^a,b   Arrobio, Julita ^a   Fink, Robert ^a   Kim, Hyun W ^a   Milburn, Cherye ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBAVIRIN;

ANTIVIRAL ACTIVITY; ARTICLE; BRONCHIOLITIS; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; HIGH RISK POPULATION; HUMAN; LUNG FUNCTION; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PULSE OXIMETRY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS INFECTION;

EID: 0032923353     PISSN: 10724710     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpedi.153.5.469     Document Type: Article

References (22)

1. Parrot RH, Kim HW, Chanock RW. Respiratory syncytial in infants and children. Prev. Med. 1984;3:473-480.
2. Rodriguez WJ, Kim HW, Brandt CD, et al. Aerosolized ribavirin in the treatment of patients with respiratory syncytial virus disease. Pediatr Infect Dis J. 1987;6:154-163.
3. Chai H, Farr RS, Froehlich LA, et al. Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol. 1975;56:323.
4. SAS/STAT User's Guide, Version 6. Vol 2. 4th ed. Cary, NC: SAS Institute Inc; 1990:1197-1210.
5. Armitage P. Statistical Methods in Medical Research. New York, NY: John Wiley & Sons Inc; 1971:135-137.
6. STATXACT 3 for Windows: Statistical Software for Exact Nonparametric Inference. Cambridge, Mass: CYTEL Software Corp; 1995.
7. Hiatt P, Treece D, Morris L, Taber L. Longitudinal pulmonary function (PF) following treatment with ribavirin in infants hospitalized with RSV bronchiolitis [abstract]. Am J Respir Crit Care Med. 1994;149:A354.
8. Rooney JC, Williams HE. The relationship between proved viral bronchiolitis and subsequent wheezing. J Pediatr. 1971;79:744-747.
9. Hall CB. Respiratory syncytial virus: what we know. Contemp Pediatr. December 31, 1993:92-106.
10. Korpi M, Kuikka L, Reijonem T, et al. Bronchial asthma and hyperactivity after early childhood bronchiolitis or pneumonia: an 8-year follow-up study. Arch Pediatr Adolesc Med. 1994;148:1079-1084.
11. Pullan CR, Hey EN. Wheezing asthma and pulmonary dysfunction 10 years after infection with respiratory syncytial in infancy. BMJ. 1982;284:1665-1669.
12. Sigurs N, Bjarnason R, Sigurbersson F, Kjellman B, Bjorsten B. Asthma and immunoglobulin E antibodies after respiratory syncytial virus bronchiolitis: a prospective cohort study with matched controls. Pediatrics. 1995;95:500-505.
13. Sims DG, Downham MAPS, Gardner PS, Webb JKG, Weightman D. Study of 8-year-old children with a history of respiratory syncytial virus bronchiolitis in infancy. BMJ. 1978;1:11-14.
14. Wiling HJ, Cranford NJ, Glaser J. The relationship between bronchiolitis and childhood asthma. J Allergy. 1959;30:19-23.
15. Eisen AH, Bacal HL. The relationship of acute bronchiolitis to bronchial asthma: a 4-14 year follow-up. Pediatrics. 1963;31:859-861.
16. Martinez F, Wright A, Taussig L, et al. Asthma and wheezing in the first six years of life. N Engl J Med. 1995;332:133-138.
17. Welliver RC, Wong OT, Sun M, et al. The development of respiratory syncytial virus specific IgE and the release of histamine in nasopharyngeal secretions after infection. N Engl J Med. 1981;305:841-846.
18. Welliver RC, Sun M, Rinaldo D, et al. Predictive value of respiratory syncytial virus specific IgE response for recurrent wheezing following bronchiolitis. J Pediatr. 1986;109:776-780.
19. Volovitz M, Welliver RC, De Castro G, et al. The release of leukotrienes in the respiratory host during infection with respiratory syncytial virus: role in obstructive airway disease. Pediatr Res. 1988;24:504-507.
20. Rosmer LK, Welliver RC, Edelson P, et al. Effect of ribavirin therapy on respiratory syncytial virus specific IgE and IgA response after infection. J Infect Dis. 1982;155:1043-1047.
21. Krilov LR, Mandel FS, Barone SR, et al. Follow-up of children with respiratory syncytial virus bronchiolitis in 1986 and 1987: potential effect of ribavirin on long-term pulmonary function. Pediatr Infect Dis J. 1997;16:173-276.
22. Long C, Voter K, Baker W, Wall C. Long-term follow-up of children hospitalized with respiratory syncytial virus lower respiratory tract infection and randomly treated with ribavirin or placebo. Pediatr Infect Dis J. 1997;16:1023-1028.