Long term follow-up of children hospitalized with respiratory syncytial virus lower respiratory tract infection and randomly treated with ribavirin or placebo

Pediatric Infectious Disease Journal

Volumn 16, Issue 11, 1997, Pages 1023-1028

  Long, Christine E ^a   Voter, Karen Z ^a   Barker, William H ^a   Hall, Caroline B ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Antivirals; Follow up; Pulmonary function; Respiratory syncytial virus; Ribavirin

Indexed keywords

OXYGEN; RIBAVIRIN;

ARTICLE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LONG TERM CARE; LOWER RESPIRATORY TRACT INFECTION; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; OXYGEN SATURATION; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SPIROMETRY;

ANTIVIRAL AGENTS; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; GROWTH; HOSPITALIZATION; HUMANS; MALE; RECURRENCE; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY TRACT INFECTIONS; RIBAVIRIN;

EID: 0030694798     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199711000-00004     Document Type: Article

References (26)

1. Heilman CA. Respiratory syncytial and parainfluenza viruses. J Infect Dis 1990;161:402-6.
2. Hall CB. Respiratory syncytial virus. In: Feigin RD, Cherry JD, eds. Textbook of pediatric infectious diseases. 3rd ed. Philadelphia: Saunders, 1992:1633-56.
3. Hall CB, McBride JT, Walsh EE, et al. Aerosolised ribavirin treatment of infants with respiratory syncytial virus infection. N Engl J Med 1983;308:1443-7.
4. Hall CB, McBride JT, Gala CL, Hildreth S, Schnabel K. Ribavirin treatment of RSV infection in infants with underlying cardiopulmonary disease. JAMA 1985;254:3047-51.
5. Taber LH, Knight V, Gilbert BE, et al. Ribavirin aerosol treatment of bronchiolitis associated with respiratory syncytial virus infection in infants. Pediatrics 1983;72:613-8.
6. Rodriguez WJ, Kim HW, Brandt CT, et al. Aerosolized ribavirin in the treatment of patients with respiratory syncytial virus disease. Pediatr Infect Dis J 1987;6:159-63.
7. Smith DW, Frankel LR, Mathers LH, Tang ATS, Ariaggno RL, Prober CG. A controlled trial of aerosolized ribavirin in infants receiving mechanical ventilation for severe respiratory syncytial virus infection. N Engl J Med 1991;325:24-9.
8. Barry W, Cockburn F, Cornall R, Price JF, Sutherland G, Vardag A. Ribavirin aerosol for acute bronchiolitis. Arch Dis Child 1986;61:593-7.
9. Janai HK, Marks MI, Zaleska M, Stutman H. Ribavirin: adverse drug reactions 1986 to 1988. Pediatr Infect Dis J 1990;9:209-11.
10. Sims D, Downham M, Gardner P, Webb J, Weightman D. Study of 8 year old children with a history of RSV bronchiolitis in infancy. Br Med J 1978;111-14.
11. Mok JYQ, Simpson H. Symptoms, atopy, and bronchial reactivity after lower respiratory infection in infancy. Arch Dis Child 1984;59:299-305.
12. Pullen CR, Hey EN. Wheezing, asthma and pulmonary dysfunction 10 years after infection with respiratory syncytial virus in infancy. Br Med J 1982;284:1665-9.
13. Voter KZ, Henry MM, Stewart PW, Henderson FW. Lower respiratory illness in early childhood and lung function and bronchial reactivity in adolescent males. Am Rev Respir Dis 1988;137:302-7.
14. Hall CB, Hall WJ, Gala CL, Magill FB, Leddy JP. Long term prospective study in children after respiratory syncytial virus infection. J Pediatr 1984;105:358-64.
15. Polgar G. Pulmonary function testing in children: techniques and standards. Philadelphia: Saunders, 1971.
16. Weng T, Levison H. Standards of pulmonary function in children. Am Rev Respir Dis 1969;99:879-94.
17. National Center for Health Statistics. NCHS growth charts. Monthly Vital Statistics Reports 1976;25(3, Suppl (HRA)):76-1120.
18. Cahan C, Decker MJ, Hoekje PL, Kingman PS. Agreement between non-invasive oximetric values for oxygen saturation. Chest 1990;97:814-9.
19. Welliver R. The relationship of RSV-specific immunoglobulin E antibody responses in infancy, recurrent wheezing, and pulmonary function at age 7-8 years. Pediatr Pulmonol 1993;15:19-27.
20. McConnochie KM, Mark JD, McBride JT, Hall WJ, Brooks JG. Normal pulmonary function measurements and airway reactivity in childhood after mild bronchiolitis. Pediatrics 1985;107:54-8.
21. Weiss ST, Tager IB, Speizer FE, Rosner B. Persistent wheeze: its relation to respiratory illness, cigarette smoking and level of pulmonary function in a population sample of children. Am Rev Respir Dis 1980;122:697-707.
22. Garofalo R, Welliver RC, Ogra P. Modulation of leukotriene (LT) release with ribavirin during infection with respiratory syncytial virus. Pediatr Res 1989;25(Part 2):163A.
23. Rosner I, Welliver R, Edelson P, Geraci-Ciardullo K, Sun M. Effect of ribavirin therapy on RSV-specific IgE and IgA responses after infection. J Infect Dis 1987;155:1043-7.
24. Krilov LR, Mandel FS, Barone SR, et al. Follow-up of children with respiratory syncytial virus bronchiolitis in 1986 and 1987: potential effect of ribavirin on long term pulmonary function. Pediatr Infect Dis J 1997;16:273-6.
25. Rodriguez WJ, Arrobio J, Fink R, Kim HW, Milburn C. Prospective(7 yrs) follow-up and pulmonary functions from a placebo controlled, randomized trial of ribavirin in RSV bronchiolitis [Abstract 183A]. Pediatr Res 1996;39: 1086.
26. Giffin FJ, Greenough A, Yuksle B. Antiviral therapy in neonatal chronic disease. Early Hum Dev 1995;42:97-109.