Photodegraded nifedipine promotes transferrin-independent gallium uptake by cultured tumor cells

Journal of Nuclear Medicine

Volumn 40, Issue 1, 1999, Pages 159-165

  Luttropp, Cheryl A ^b   Vu, Chau ^b   Morton, Kathryn A ^a  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

Cultured tumor cells; Gallium isotopes; Photodegraded nifedipine

Indexed keywords

GALLIUM 67; NIFEDIPINE; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ARTICLE; CANCER DIAGNOSIS; CHO CELL; NONHUMAN; PHOTODEGRADATION; PRIORITY JOURNAL; TUMOR CELL; TUMOR CELL CULTURE; ULTRAVIOLET RADIATION;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CRICETINAE; GALLIUM RADIOISOTOPES; LIGHT; NIFEDIPINE; PHOTOCHEMISTRY; TRANSFERRIN; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

EID: 0032922784     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Edwards CL, Haves RL. Tumor scanning with 67Ga citrate. J Nucl Med. 1969;10:103-105.
2. Halpern S, Hagan P. Gallium-67 citrate imaging in neoplastic and inflammatory disease. In: Freeman LM, Weissman HS, eds. Nuclear Medicine Annual. New York, NY: Raven Press; 1980:219-265.
3. Beckerman C, Hoffer PB, Bitran JD. The role of gallium-67 in the clinical evaluation of cancer. Semin Nucl Med. 1985;15:72-103.
4. Andrrson KC, Leonard RCF, Canellos GP, et al. High-dose gallium imaging in lymphoma. Am J Med. 1983;75:327-331.
5. Israel O, Front D, Epelbaum R, et al. Residual mass and negative gallium scintigraphy in treated lymphoma. J Nucl Med. 1990;31:365-368.
6. Kaplan WD. Residual mass and negative gallium scintigraphy in treated lymphoma: when is the gallium scan really negative [Editorial]? J Nucl Med. 1990;31:369-371.
7. Front D, Isreal O. The role of Ga-67 scintigraphy in evaluating the results of therapy of lymphoma patients. Semin Nucl Med. 1995;25:60-71.
8. Front D, Bar-Shalom R, Israel O. The continuing clinical role of gallium-67 scintigraphy in the age of receptor imaging. Semin Nucl Med. 1997;27:68-74.
9. Rossleigh MA, Murray PC, Mackey DWJ, Bargwanna KA, Nayanar VV. Pediatric solid tumors: evaluation by gallium-67 SPECT studies. J Nucl Med. 1990;31:168-172.
10. Hoffer P. Gallium: mechanisms. J Nucl Med. 1990;21:282-285.
11. Harris AW, Sephton RG. Transferrin promotion of 67Ga and 59Fe uptake by cultured mouse myeloma cells. Cancer Res. 1977;37:3635-3638.
12. Larson SM, Rasey JS, Allen DR, et al. A transferrin-mediated uptake of gallium-67 by EMT-6 sarcoma. I. Studies in tissue culture. J Nucl Med. 1979;20:837-842.
13. Chitambar CR, Sax D. Regulatory effects of gallium on transferrin-independent iron uptake by human leukemic HL60 cells. Blood. 1992;80:505-511.
14. Otten J, Johnson GS, Paslen I. Cyclic AMP levels in fibroblasts: relationship to growth rate and contact inhihition of growth. Proc Soc Exp Biol Med. 1973;142: 92-95.
15. Wong H, Terner UK, English D, et al. The role of transform in the in vivo uptake of gallium-67 in a canine tumor. Int J Nucl Med Biol. 1980;7:9-16.
16. Sohn M-H, Jones BJ, Whiting JH Jr, Datz FL, Lynch RE, Morton KA. Distribution of gallium-67 in normal and hypotransferrinemic tumor-bearing mice. J Nucl Med. 1993;34:2135-2143.
17. Luttropp CA, Jackson JA, Jones BJ, Sohn M-H, Lynch RE, Morton KA. Uptake of gallium-67 in transfected cells and tumors absent or enriched in the transferrin receptor. J Nucl Med. 1998;39:1405-1411.
18. Phelouzat M-A, Basselin M, Lawrence F, Robert-Gero M. Sinefungin shares AdoMct-uptake system to enter Leishmania donovani promastigotes. Biochem J. 1995;305:133-137.
19. Leo A, Hansch C, Elkins D. Partition coefficients and their uses. Chem Rev. 1971;71:525-616.
20. Smith RN, Hansch C, Ames MW. Selection of a reference partitioning system for drug design work. J Pharm Sci. 1975;64:599-606.
21. Triggle DJ. Calcium channel antagonists: mechanism of action, vascular selectivities, and clinical relevance. Clevel Clin J Med. 1995;59:617-627.
22. Berson JA, Brown E. Studies on dihydropyridines. II. The photochemical disproportionate of 4-(2′-nitrophenyl)-1,4-dihydropyridines. J Am Chem Soc. 1955;77:447-450.
23. Majeed IA, Murray WJ, Newton DW, Othman S, Al-turk WA. Spectrophotometric study of the photodecomposition kinetics of nifedipine. J Pharm Pharmacol. 1987;39:1044-1046.
24. Hayase N, Itagaki Y-I, Ogawa S, Akutsu S, Inagaki S-I, Abiko U. Newly discovered photodegradation products of nifedipine in hospital prescriptions. J Pharm Sci. 1994;83:532-538.
25. Grundy JS, Kherani R, Foster RT. Photostability determination of commercially available nifedipine oral dosage formulations. J Pharm Biomed Anal. 1994;12: 1529-1535.
26. Nerbonne JM, Richard S, Nargeot J. Calcium channels are "unblocked" within a few milliseconds after photoremoval of nifedipine. J Mol Cell Cardiol. 1985;17: 511-515.
27. Lovren F, O'Neill SK, Dieger D, Igbal N, Knaus EE, Triggle CR, Nitric oxide, a possible mediator of 1,4-dihydropyridine-induced photorelaxation of vascular smooth muscle. Br J Pharmacol. 1996;118:879-884.
28. Hayase N, Inagaki S-I, Abiko Y. Effects of photodegradation products of nifedipine: the nitroso-derivative relaxes contraction of the rat aortic strip induced by norepinephrine and other agonists. J Pharmacol Exp Ther. 1995;275:813-821.
29. Savigni DL, Morgan EH. Mediation of iron uptake and release in erythroid cells by photodegradation products of nifedipine. Biochem Pharmacol. 1996;51:1701-1709.
30. Cotton FA, Wilkinson G. Advanced Inorganic Chemistry, 5th ed. New York, NY: Interscience; 1988:543-545.
31. Sturrock A, Alexander J, Lamb J, Craven CM, Kaplan J. Characterization of a transferrin-independent uptake system for iron in HeLa cells. J Biol Chem. 1990;265:3139-3145.
32. Kaplan J, Jordan I, Sturrock A. Regulation of the transferrin-independent iron transport system in cultured cells. J Biol Chem. 1991;266:2997-3004.
33. Jordan I, Kaplan J. The mammalian transferrin-independenl iron transport system may involve a surface ferrireductase activity. Biochem J. 1994;302:875-879.
34. Inman RS, Coughlan MM, Wessling-Resnick M. Extracellular ferrireductase activity of K562 cells is coupled to transferrin independent iron transport. Biochemistry. 1994;33:11850-11857.
35. Chitambar CR, Zivkovic Z. Uptake of gallium-67 by human leukemic cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms. Cancer Res. 1987;47:3929-3934.