Mediation of iron uptake and release in erythroid cells by photodegradation products of nifedipine

Biochemical Pharmacology

Volumn 51, Issue 12, 1996, Pages 1701-1709

  Savigni, Donna L ^a   Morgan, Evan H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Ca2+ antagonists; erythroid cells; iron transport; nitrosophenyl pyridine; photodegraded nifedipine

Indexed keywords

CALCIUM ANTAGONIST; CINNARIZINE; DEFEROXAMINE; DILTIAZEM; IONOPHORE; IRON; IRON 59; MANGANESE; NICARDIPINE; NIFEDIPINE; NITROSOPYRIDINE DERIVATIVE; TRANSFERRIN; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CHELATION THERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RELEASE; DRUG UPTAKE; ERYTHROCYTE; ERYTHROID CELL; IRON TRANSPORT; NONHUMAN; PHOTODEGRADATION; PRIORITY JOURNAL; RABBIT; RETICULOCYTE;

EID: 0029888395     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00164-5     Document Type: Article

References (18)

1. Morgan EH, Transferrin, biochemistry, physiology and clinical significance. Mol Aspects Med 34: 1-122, 1981.
2. Morgan EH, Membrane transport of non-transferrin-bound iron by reticulocytes. Biochim Biophys Acta 943: 428-439, 1988.
3. Hodgson LL, Quail EA and Morgan EH, Iron transport mechanisms in reticulocytes and mature erythrocytes. J Cell Physiol 162: 181-190, 1995.
4. Hemmaplardh D and Morgan EH, The role of calcium in transferrin and iron uptake by reticulocytes. Biochim Biophys Acta 468: 423-436, 1977.
5. Morgan EH, Calcium chelators induce association with the detergent-insoluble cytoskeleton and functional inactivation of the transferrin receptor in reticulocytes. Biochim Biophys Acta 981: 121-129, 1989.
6. Winegar BD, Kelly R and Lansman JB, Block of current through single calcium channels by Fe, Co and Ni. Location of the transition metal binding site in the pore. J Gen Physiol 97: 351-367, 1991.
7. Triggle DJ, Calcium, calcium channels, and calcium channel antagonists. Can J Physiol Pharmacol 68: 1474-1481, 1990.
8. 2+ channel interaction. Trends Pharmacol Sci 11: 38-44, 1990.
9. Plageman PGW and Woffendin C, Effects of calcium-channel antagonists on nucleoside and nucleobase transport in human erythrocytes and cultured mammalian cells. Biochim Biophys Acta 928: 243-250, 1987.
10. Hemmaplardh D and Morgan EH, The mechanism of iron exchange between synthetic iron chelators and rabbit reticulocytes. Biochim Biophys Acta 373: 84-89, 1974.
11. 59Fe in hemin in peripheral red cells and red cells in bone marrow cultures. Clin Chim Acta 11: 321-333, 1965.
12. Berson JA and Brown E, Studies on dehydropyridines. II. The photochemical disproportion of 4-(2′-nitrophenyl)-1,4 dihydropyridines. J Am Chem Soc 77: 447-450, 1955.
13. Jakobsen P, Pedersen OL and Mikkelsen E, Gas chromatographic determination of nifedipine and one of its metabolites using electron capture detection. J Chromatogr 162: 81-87, 1979.
14. Majeed IA, Murray WJ, Newton DW, Othamn S and Al-Turk WA, Spectrophotometric study of the photodecomposition kinetics of nifedipine. J Pharm Pharmacol 39: 1044-1046, 1987.
15. Borova J, Ponka P and Neuwirt J, Study of intracellular iron distribution in rabbit reticulocytes with normal and inhibited heme synthesis. Biochim Biophys Acta 320: 143-156, 1973.
16. Baker E and Morgan EH, Iron transport.In: Iron Metabolism and Health and Disease (Eds. Brock JH, Halliday JW, Pippard MJ and Powell LW), pp. 63-95. Saunders, London, 1994.
17. Sanguinetti MC and Kass RS, Photoalteration of calcium channel blockade in the cardiac Purkinje fiber. Biophys J 45: 873-880, 1984.
18. Gurney AM, Nerbonne JM and Lester HA, Photoinduced removal of nifedipine reveals mechanisms of calcium antagonist action in single heart cells. J Gen Physiol 86: 353-379, 1985.