Propofol administration reduces hippocampal neuronal damage induced by kainic acid in rats

Neurological Research

Volumn 21, Issue 2, 1999, Pages 225-228

  Lee, Seong Ryong ^a   Cheun, Jae Kyu ^a  

^a Keimyung University   (South Korea)

Author keywords

Excitotoxicity; Kainic acid; Neuroprotection; Propofol

Indexed keywords

INTRALIPOS; KAINIC ACID; PROPOFOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRIC ACTIVITY; HIPPOCAMPUS; HISTOPATHOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; RAT;

EID: 0032921343     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1080/01616412.1999.11740922     Document Type: Article

References (28)

1. Beveniste H, Drejer J, Schousbe A, Deimer NH. Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984; 43: 1369-1374
2. Choi DW, Rothman SM. Role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990; 13: 171-182
3. Winn P, Stone TW, Latimer M, Hastings MH, Clark AJM. A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat. Br J Pharmacol 1991; 102: 904-908
4. Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy. Neuroscience 1985; 14: 375-403
5. Young AB, Fagg GE. Excitatory amino acid receptors in the brain: Membrane binding and receptor autoradiographic approaches. Trends Pharmacol Sci 1990; 11: 126-133
6. Sebel PS, Lowdon JD. Propofol: A new intravenous anesthetic. Anesthesiology 1989; 71: 260-277
7. Smith I, White PF, Nathanson M, Gouldson R. Propofol. An update on its clincial use. Anesthesiology 1994; 81: 1005-1043
8. Dam M, Ori C, Pizzolato G, Ricchieri GL, Pellegrini A, Giron GP, Battistin L. The effects of propofol anesthesia on local cerebral glucose utilization in the rat. Anesthesiology 1990; 80: 499-505
9. Werner C, Hoffman WE, Kochs E, Albrecht RF, Esch J. The effects of propofol on cerebral blood flow in correlation to cerebral blood flow velocity in dogs (abstract). Anesthesiology 1990; 73: A556
10. Kochs E, Hoffman WE, Werner C, Thomas C, Albrecht RF, Esch J. The effects of propofol on brain electrical activity. Neurologic outcome and neuronal damage following incomplete ischemia in rats. Anesthesiology 1992; 76: 245-252
11. Hans P, Bonhomme V, Collette J, Albert A, Moonen G. Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity. J Neurosurg Anesthesiol 1994; 6: 249-253
12. Ridenour TC, Warner DS, Todd RM, Gionet TX. Comparative effects of propofol and halothane on outcome from temporary middle cerebral artery occlusion in the rat. Anesthesiology 1992; 76: 807-812
13. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates, edn 4, San Diego: Academic Press, 1998
14. Eke A, Conger KA, Anderson M. Histological assessment of neurons in rat model of cerebral ischemia. Stroke 1990; 21: 299-304
15. Bansinath M, Shukla VK, Turndorf H. Propofol modulates the effects of chemoconvulsants acting at GABAergic, glycinergic, and glutamate receptor subtypes. Anesthesiology 1995; 83: 809-815
16. Bianchi M, Battistin T, Galzigna L. 2,6-Diisopropylphenol, a general anesthetic, inhibits glutamate action on rat synaptosomes. Neurochem Res 1991; 16: 443-446
17. Zhu H, Cottrell JE, Kass IS. The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity. Anesthesiology 1997; 87: 944-951
18. Collins GGS. Effects of anaesthetic 2,6-diisopropylphenol on synaptic transmission in the rat olfactory cortex slice. Br J Pharmacol 1988; 95: 939-949
19. Peduto VA, Concas A, Santoro G, Biggio G, Gessa GL. Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology 1991; 75: 1000-1009
20. Borgeat A, Wilder-Smith OHG, Suter PM. The nonhypnotic therapeutic applications of propofol. Anesthesiology 1994; 80: 642-656
21. Hollrigel GS, Toth K, Soltesz I. Neuroprotection by propofol in acute mechanical injury: Role of GABAergic inhibition. J Neurophysiol 1996; 76: 2412-2422
22. Pitt-Miller P, Elcock B, Maharaj M. The management of status epilepticus with a continuous propofol infusion. Anesth Analg 1994; 78: 1193-1194
23. Mackenzie SJ, Kapadia F, Grant IS. Propofol infusion for control of status epilepticus. Anaesthesia 1990; 45: 1043-1045
24. Sperk G. Kainic acid seizures in the rat. Progress Neurobiol 1994; 42: 1-32
25. Bondy SC, Lee DK. Oxidative stress induced by glutamate receptor agonists. Brain Res 1993; 610: 229-233
26. Tsirka SE, Gualandris A, Amaral DG, Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature (London) 1995; 377: 340-344
27. Murphy PG, Davies MJ, Columb MO, Stratford N. Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte. Br J Anaesth 1996; 76: 536-543
28. Kahramans S, Demiryürek AT. Propofol is a peroxynitrite scavenger. Anesth Analg 1997; 84: 1127-1129