메뉴 건너뛰기




Volumn 48, Issue 1, 1999, Pages 29-38

Production and characterization of an anti-(MUC1 mucin) recombinant diabody

Author keywords

Diabody; Immunotherapy; MUC1; Mucin; scFv

Indexed keywords

GLYCOPROTEIN; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY C595; MUCIN; UNCLASSIFIED DRUG;

EID: 0032919498     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002620050545     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 0031942906 scopus 로고    scopus 로고
    • Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu
    • 1. Adams GP, Schier R, Mccall AM, Crawford RS, Wolf EJ, Weiner LM, Marks JD (1998) Prolonged in vivo tumour retention of a human diabody targeting the extracellular domain of human HER2/neu . Br J Cancer 77:1405
    • (1998) Br J Cancer , vol.77 , pp. 1405
    • Adams, G.P.1    Schier, R.2    Mccall, A.M.3    Crawford, R.S.4    Wolf, E.J.5    Weiner, L.M.6    Marks, J.D.7
  • 3
    • 0028574387 scopus 로고
    • Prognostic value in predicting overall survival of two mucinous markers: CA 15-3 and CA 125 in breast cancer patients at first relapse of disease
    • 3. Berruti A, Tampellini M, Torta M, Buniva T, Gorzegno G, Dogliotti L (1994) Prognostic value in predicting overall survival of two mucinous markers: CA 15-3 and CA 125 in breast cancer patients at first relapse of disease. Eur J Cancer 30A:2082
    • (1994) Eur J Cancer , vol.30 A , pp. 2082
    • Berruti, A.1    Tampellini, M.2    Torta, M.3    Buniva, T.4    Gorzegno, G.5    Dogliotti, L.6
  • 5
    • 0027362816 scopus 로고
    • Epithelial mucin core antigen (EMCA) in assessing therapeutic response in advanced breast cancer - A comparison with CA15.3
    • 5. Dixon AR, Price MR, Hand CW, Sibley PEC, Selby C, Blamey RW (1993) Epithelial mucin core antigen (EMCA) in assessing therapeutic response in advanced breast cancer - a comparison with CA15.3, Br J Cancer 68:947
    • (1993) Br J Cancer , vol.68 , pp. 947
    • Dixon, A.R.1    Price, M.R.2    Hand, C.W.3    Sibley, P.E.C.4    Selby, C.5    Blamey, R.W.6
  • 6
    • 0028875822 scopus 로고
    • Identification of an HLA-A11 restricted epitope from the tandem repeat domain of the epithelial tumour-antigen mucin
    • 6. Domenech N, Henderson RA, Finn OJ (1995) Identification of an HLA-A11 restricted epitope from the tandem repeat domain of the epithelial tumour-antigen mucin. J Immunol 155:4766
    • (1995) J Immunol , vol.155 , pp. 4766
    • Domenech, N.1    Henderson, R.A.2    Finn, O.J.3
  • 7
    • 0023741252 scopus 로고
    • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • 7. Gendler S, Taylor-Papadimitriou J, Duhig T, Rothbard J, Burchell J (1988) A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 263:12820
    • (1988) J Biol Chem , vol.263 , pp. 12820
    • Gendler, S.1    Taylor-Papadimitriou, J.2    Duhig, T.3    Rothbard, J.4    Burchell, J.5
  • 9
    • 0027197493 scopus 로고
    • "Diabodies": Small bivalent and bispecific antibody fragments
    • 9. Holliger P, Prospero T, Winter G (1993) "Diabodies": small bivalent and bispecific antibody fragments. Proc Natl Acad Sci USA 90:6444
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6444
    • Holliger, P.1    Prospero, T.2    Winter, G.3
  • 11
    • 0025834851 scopus 로고
    • Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognise an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells
    • 11. Jerome KR, Barnd DL, Bendt KM, Boyer CM, Taylor-Papadimitriou J, McKenzie IFC, Bast RC, Finn OJ (1991) Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognise an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells. Cancer Res 51:2908
    • (1991) Cancer Res , vol.51 , pp. 2908
    • Jerome, K.R.1    Barnd, D.L.2    Bendt, K.M.3    Boyer, C.M.4    Taylor-Papadimitriou, J.5    McKenzie, I.F.C.6    Bast, R.C.7    Finn, O.J.8
  • 12
    • 0028235908 scopus 로고
    • Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic and colon cancer patients
    • 12. Kotera Y, Fontenot JD, Pecher G, Metzgar RS, Finn OJ (1994) Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic and colon cancer patients. Cancer Res 54:2856
    • (1994) Cancer Res , vol.54 , pp. 2856
    • Kotera, Y.1    Fontenot, J.D.2    Pecher, G.3    Metzgar, R.S.4    Finn, O.J.5
  • 13
    • 0013537622 scopus 로고
    • Targeting of bladder cancer with radiolabelled monoclonal antibody NCRC-48 - A novel approach for intravesical therapy
    • 13. Kunkler RB, Bishop MC, Green DJ, Pimm MV, Price MR, Frier M (1995) Targeting of bladder cancer with radiolabelled monoclonal antibody NCRC-48 - a novel approach for intravesical therapy. Br J Urol 75:9
    • (1995) Br J Urol , vol.75 , pp. 9
    • Kunkler, R.B.1    Bishop, M.C.2    Green, D.J.3    Pimm, M.V.4    Price, M.R.5    Frier, M.6
  • 14
    • 0029069430 scopus 로고
    • Retargeting of CTL by an efficiently refolded bispecific single chain Fv dimer produced in bacteria
    • 14. Kurucz I, Titus JA, Jost CR, Jacobus CM, Segal DM (1995) Retargeting of CTL by an efficiently refolded bispecific single chain Fv dimer produced in bacteria. J Immunol 154:4576
    • (1995) J Immunol , vol.154 , pp. 4576
    • Kurucz, I.1    Titus, J.A.2    Jost, C.R.3    Jacobus, C.M.4    Segal, D.M.5
  • 16
    • 0029148633 scopus 로고
    • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
    • 16. Mack M, Riethmuller G, Kufer P (1995) A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc Natl Acad Sci USA 92:7021
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7021
    • Mack, M.1    Riethmuller, G.2    Kufer, P.3
  • 17
    • 0028140247 scopus 로고
    • Construction, expression and activity of a bivalent bispecific single-chain antibody
    • 17. Mallender WD, Voss EW Jr (1994) Construction, expression and activity of a bivalent bispecific single-chain antibody. J Biol Chem 269:199
    • (1994) J Biol Chem , vol.269 , pp. 199
    • Mallender, W.D.1    Voss E.W., Jr.2
  • 18
    • 0028886481 scopus 로고
    • CEA, MCA CA 15.3 and CA 549 and their combinations in expressing and monitoring metastatic breast cancer: A prospective comparative study
    • 18. Martoni A, Zamagni C, Bellanova B, Zanichelli L, Vecchi F, Cacciari N, Strocchi E, Pannuti F (1995) CEA, MCA CA 15.3 and CA 549 and their combinations in expressing and monitoring metastatic breast cancer: a prospective comparative study. Eur J Cancer 31:1615
    • (1995) Eur J Cancer , vol.31 , pp. 1615
    • Martoni, A.1    Zamagni, C.2    Bellanova, B.3    Zanichelli, L.4    Vecchi, F.5    Cacciari, N.6    Strocchi, E.7    Pannuti, F.8
  • 19
    • 0025226085 scopus 로고
    • Phage antibodies: Filamentous phage displaying antibody variable domains
    • 19. McCafferty J, Griffiths AD, Winter G, Chiswell DJ (1990) Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348:552
    • (1990) Nature , vol.348 , pp. 552
    • McCafferty, J.1    Griffiths, A.D.2    Winter, G.3    Chiswell, D.J.4
  • 20
    • 0025323102 scopus 로고
    • Polymorphic epithelial mucin from the sera of advanced breast cancer patients-isolation and partial characterisation
    • 20. O'Sullivan C, Price MR, Baldwin RW (1990) Polymorphic epithelial mucin from the sera of advanced breast cancer patients-isolation and partial characterisation. Br J Cancer 61:801
    • (1990) Br J Cancer , vol.61 , pp. 801
    • O'Sullivan, C.1    Price, M.R.2    Baldwin, R.W.3
  • 21
    • 0026528230 scopus 로고
    • Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric Fv fragments with high avidity in Escherichia coli
    • 21. Pack P, Pluckthun A (1992) Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric Fv fragments with high avidity in Escherichia coli. Biochem 31:1579
    • (1992) Biochem , vol.31 , pp. 1579
    • Pack, P.1    Pluckthun, A.2
  • 22
    • 0027319517 scopus 로고
    • Immunoscintigraphy of ovarian carcinoma using a monoclonal antibody (In-111-NCRC-48) defining polymorphic epithelial mucin
    • 22. Perkins AC, Symonds IM, Pimm MV, Price MR, Wastie ML, Symonds EM (1993) Immunoscintigraphy of ovarian carcinoma using a monoclonal antibody (In-111-NCRC-48) defining polymorphic epithelial mucin. Nucl Med Commun 14:578
    • (1993) Nucl Med Commun , vol.14 , pp. 578
    • Perkins, A.C.1    Symonds, I.M.2    Pimm, M.V.3    Price, M.R.4    Wastie, M.L.5    Symonds, E.M.6
  • 23
    • 0027241333 scopus 로고
    • Polymorphic epithelial mucins (PEM): Molecular characteristics and association with breast cancer
    • 23. Price MR, Tendler SJB (1993) Polymorphic epithelial mucins (PEM): molecular characteristics and association with breast cancer. Breast 2:3
    • (1993) Breast , vol.2 , pp. 3
    • Price, M.R.1    Tendler, S.J.B.2
  • 24
    • 0025321809 scopus 로고
    • C595 - A monoclonal antibody against the protein core of human urinary epithelial mucin commonly expressed in breast carcinomas
    • 24. Price MR, Pugh JA, Hudecz F, Griffiths W, Jacobs E, Clarke AJ, Chan WC, Baldwin RW (1990) C595 - a monoclonal antibody against the protein core of human urinary epithelial mucin commonly expressed in breast carcinomas. Br J Cancer 61:681
    • (1990) Br J Cancer , vol.61 , pp. 681
    • Price, M.R.1    Pugh, J.A.2    Hudecz, F.3    Griffiths, W.4    Jacobs, E.5    Clarke, A.J.6    Chan, W.C.7    Baldwin, R.W.8
  • 25
    • 0025801974 scopus 로고
    • Purification of anti-epithelial mucin monoclonal antibodies by epitope affinity chromatography
    • 25. Price MR, Sekowski M, Tendler SJB (1991) Purification of anti-epithelial mucin monoclonal antibodies by epitope affinity chromatography. J Immunol Methods 139:83
    • (1991) J Immunol Methods , vol.139 , pp. 83
    • Price, M.R.1    Sekowski, M.2    Tendler, S.J.B.3
  • 31
    • 0026684815 scopus 로고
    • Rapid tumor penetration of a single chain Fv and comparison with other immunoglobulin forms
    • 31. Yokota T, Milenic DE, Whitlow M, Schlom J (1992) Rapid tumor penetration of a single chain Fv and comparison with other immunoglobulin forms. Cancer Res 52:3402
    • (1992) Cancer Res , vol.52 , pp. 3402
    • Yokota, T.1    Milenic, D.E.2    Whitlow, M.3    Schlom, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.