Evidence for superantigen involvement in skin homing of T cells in atopic dermatitis

Journal of Investigative Dermatology

Volumn 112, Issue 2, 1999, Pages 249-253

  Strickland, Ian ^a   Hauk, Pia J ^a   Trumble, Anne E ^a   Picker, Louis J ^b   Leung, Donald Y M ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

CLA; Inflammation; SEB; TSST 1

Indexed keywords

BACTERIAL ANTIGEN; SUPERANTIGEN;

ADULT; ALLERGENICITY; ANTIGEN ANTIBODY REACTION; ARTICLE; ATOPIC DERMATITIS; CLINICAL ARTICLE; HUMAN; IMMUNOPATHOGENESIS; LYMPHOCYTE HOMING; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE ACTIVATION;

EID: 0032918376     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1999.00502.x     Document Type: Article

References (27)

1. Abe J, Kotzin BL, Meissner C, et al: Characterization of T cell repertoire changes in acute Kawasaki disease. J Exp Med 177:791-796, 1993
2. Abernathy-Carver KJ, Sampson HA, Picker LJ, Leung DYM: Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 95:913-918, 1995
3. Brosius DL, Newburger JC, Burns JC, Hojnowski-Diaz P, Zierler S, Leung DYM: Increased prevalence of atopic dermatitis in Kawasaki disease. J Ped Infect Dis 7:863-866, 1988
4. Grewe M, Gyufko K, Schopf E, Krutmann J: Lesional expression of interferon- gamma in atopic eczema. Lancet 343:25-26, 1994
5. Hamid Q, Boguniewicz M, Leung DYM: Differential in situ cytokine gene expression in acute vs. chronic atopic dermatitis. J Clin Invest 94:870-876, 1994
6. Hamid Q, Naseer T, Minshall EM, Song YL, Boguniewicz M, Leung DYM: In vivo expression of IL-12 and IL-13 in atopic dermatitis. J Allergy Clin Immunol 98:225-231, 1996
7. Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Dermatol Venereol (Stockh) 92:44-47, 1980
8. Herz U, Schnoy N, Borelli S, et al: A human-SCID mouse model for allergic immune responses: Bacterial superantigen enhances skin inflammation and suppresses IgE production. J Invest Dermatol 110:224-231, 1998
9. Jozefckz Z: Specific human antibodies to eneterotoxins A, B and C of Staphylococcus: their increased synthesis in staphylococcal infection. J Infect Dis 130:1-7, 1974
10. Kotzin BL, Leung DYM, Kappler J, Marrack P: Superantigens and their potential role in human disease. Adv Immunol 54:99-166, 1993
11. Lester MR, Hofer MF, Gately M, Trumble AE, Leung DYM: Down-regulating effects of IL-4 and IL-10 on the IFN-gamma response in atopic dermatitis. J Immunol 154:6174-6181, 1995
12. Leung DYM: Atopic dermatitis: the skin as a window into the pathogenesis of chrome allergic diseases. J Allergy Clin Immunol 96:302-318;, 1995
13. Leung DYM, Harbeck H, Bina P, et al: Presence of IgE antibodies to staphylococcal enterotoxins on the skin of patients with atopic dermatitis: evidence for a new group of allergens. J Clin Invest 92:1374-1380, 1993a
14. Leung DYM, Meissner HC, Fulton DR, Murray DL, Kotzin BL, Schlievert PM: Toxic shock syndrome toxin X secreting Staphylococcus aureus in Kawasaki syndrome. Lancet 342:1385-1388, 1993b
15. Leung DYM, Gately M, Trumble AE, Ferguson-Darnell B, Schlievert PM, Picker LJ: Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med 181:747-753, 1995
16. Lever R, Hadley K, Downey D, Mackie R: Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy. Br J Dermatol 119:189- 198, 1988
17. Leyden JE, Marples RR, Kligman AM: Staphylococcus aureus in the lesions of atopic dermatitis. Br J Dermatol 90:525-530, 1974
18. Marrack P, Kappler J: The staphylococcal enterotoxins and their relatives. Science 248:705-711, 1990
19. McFadden JP, Noble WC, Camp RD: Superantigenic exotoxin-secreting potential of staphylococci isolated from atopic eczematous skin. Br J Dermatol 128:631- 632, 1993
20. Michie CA, Davis T: Atopic dermatitis and staphylococcal superantigens. Lancet 347:324, 1996
21. Neuber K, Loliger C, Kohler I, Ring J: Preferential expression of T-cell receptor V beta-chains in atopic eczema. Acta Derm Venereol 76:214-218, 1996
22. Santamaria-Babi LF, Picker LJ, Perez Soler MT, Drzimalla K, Flohr P, Blaser K, Hauser C: Circulating allergen-reactive T cells from patients with atopic dermatitis and allergic contact dermatitis express the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen. J Exp Med 181:1935- 1940, 1995
23. Schultz-Larsen F, Holm NV, Henningsen K: Atopic dermatitis. A genetic-epidemiologic study in a population based twin sample. J Am Acad Derm 15:487-494, 1986
24. Strange P, Skov L, Lisby S, Nielsen PL, Baadsgaard O: Staphylococcal enterotoxin B applied on intact normal and intact atopic skin induces dermatitis. Arch Dermatol 132:27-33, 1996
25. Tada J, Toi Y, Akiyama H, Arata J: Presence of specific IgE antibodies to staphylococcal enetertoxins in patients with atopic dermatitis. Eur J Dermatol 6:552-554, 1996
26. + allergen-specific T lymphocytes in atopic dermatitis lesional skin. J Invest Dermatol 97:389-394, 1991
27. Wu CY, Demeure C, Kiniwa M, Gately M, Delespesse G: IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells. J Immunol 151:1938-1949, 1993