Steroidogenic enzyme expression in human corpora lutea in the presence and absence of exogenous human chorionic gonadotrophin (HCG)

Molecular Human Reproduction

Volumn 5, Issue 4, 1999, Pages 291-298

  Duncan, W Colin ^a   Cowen, Gwen M ^a   Illingworth, Peter J ^a,b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Corpus luteum; Enzymes; HCG; Steroidogenesis; Steroidogenic acute regulatory protein

Indexed keywords

CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CHORIONIC GONADOTROPIN; CYTOCHROME P450; PROGESTERONE; REGULATOR PROTEIN; STEROIDOGENIC ACUTE REGULATORY PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CORPUS LUTEUM FUNCTION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYSTERECTOMY; IMMUNOHISTOCHEMISTRY; LUTEINIZING HORMONE RELEASE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STEROIDOGENESIS;

EID: 0032917134     PISSN: 13609947     EISSN: None     Source Type: Journal    
DOI: 10.1093/molehr/5.4.291     Document Type: Article

References (49)

1. Bassett, S.G., Little-Ihrig, L.L., Mason, J.I. and Zeleznik, A.J. (1991) Expression of messenger ribonucleic acids that encode for 3β-hydroxysteroid dehydrogenase and cholesterol side-chain cleavage enzyme throughout the luteal phase of the macaque menstrual cycle. J. Clin. Endocrinol. Metab., 72, 362-366.
2. Behrman, H.R., Endo, T., Aten, R.F. and Musicki, B. (1993) Corpus luteum function and regression. Reprod. Med. Rev., 2, 153-180.
3. Bramley, T.A., Stirling, D., Swanston, I.A. et al. (1987) Specific binding sites for gonadotrophin-releasing hormone, LH/chorionic gonadotrophin, low-density lipoprotein, prolactin and FSH in homogenates of human corpus luteum. II: Concentrations throughout the luteal phase of the menstrual cycle and early pregnancy. J. Endocrinol., 113, 317-327.
4. Brännström, M. and Norman, R.J. (1993) Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function. Hum. Reprod., 8, 1762-1775.
5. Brooks, J., Crow, W.J., McNeilly, J.R. and McNeilly, A.S. (1992) Relationship between gonadotropin subunit gene-expression, gonadotropin-releasing hormone receptor content and pituitary and plasma gonadotropin concentrations during the rebound release of FSH after treatment of ewes with bovine follicular-fluid during the luteal phase of the cycle. J. Mol. Endocrinol., 8, 109-118.
6. Carr, B.R., MacDonald, P.C. and Simpson, E.R. (1982) The role of lipoproteins in the regulation of progesterone secretion by the corpus luteum. Fertil. Steril., 38, 303-311.
7. Chavatte, P.M., Rossdale, P.D. and Tait, A.D. (1995) Modulation of 3β-hydroxysteroid dehydrogenase (3β-HSD) activity in the equine placenta by pregnenolone and progesterone metabolites. Equine Vet J., 5, 342-347.
8. Chedrese, P.J., The, V.L., Labrie, F. et al. (1990) Evidence for the regulation of 3β-hydroxysteroid dehydrogenase messenger RNA by human chorionic gonadotropin in luteinized porcine granulosa cells. Endocrinology, 126, 2228-2230.
9. Chomczynski, P. and Sacchi, N. (1987) Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
10. Clark, B.J., Wells, J., King, S.R. and Stocco, D.M. (1994) The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse leydig tumor cells. J. Biol. Chem., 269, 28314-28322.
11. Cole, F.E., Weed, J.C., Schneider, G.T. et al. (1973) The gonadotropin receptor of the human corpus luteum. Am. J. Obstet. Gynecol., 117, 87-95.
12. Conley, A.J., Kaminski, M.A., Dubowsky, S.A. et al. (1995) Immunohistochemical localization of 3β-hydroxysteroid dehydrogenase and P450 17α-hydroxylase during follicular and luteal development in pigs, sheep and cows. Biol Reprod., 52, 1081-1094.
13. Djahanbakhch, O., McNeilly, A.S., Hobson, B.M. and Templeton, A.A. (1981a) A rapid luteinizing hormone radioimmunoassay for the prediction of ovulation. Br. J. Obstet. Gynaecol., 88, 1016-1020.
14. Djahanbakhch, O., Swanston, I.A., Corrie, J.E.T. and McNeilly, A.S. (1981b) Prediction of ovulation by progesterone. Lancet, ii, 1164-1165.
15. Doody, K.J., Lorence, M.C., Mason, J.I. and Simpson, E.R. (1990) Expression of messenger ribonucleic acid species encoding steroidogenic enzymes in human follicles and corpora lutea throughout the menstrual cycle. J. Clin. Endocrinol Metab., 70, 1041-1045.
16. Duffy, D.M., Hess, D.L. and Stouffer, R.L. (1994) Acute administration of a 3β-hydroxysteroid dehydrogenase inhibitor to rhesus monkeys at the midluteal phase of the menstrual cycle: evidence for possible autocrine regulation of the primate corpus luteum by progesterone. J. Clin. Endocrinol. Metab., 79, 1587-1594.
17. Duffy, D.M., Stouffer, R.L. and Stewart, D.R. (1995) Dissociation of relaxin and progesterone secretion from the primate corpus luteum by acute administration of a 3β-hydroxysteroid dehydrogenase inhibitor during the menstrual cycle. Biol. Reprod., 53, 447-453.
18. Duncan, W.C., McNeilly, A.S., Fraser, H.M. and Illingworth. P.J. (1996a) Luteinizing hormone receptor in the human corpus luteum: lack of down-regulation during maternal recognition of pregnancy. Hum. Reprod., 11, 2291-2297.
19. Duncan, W.C., McNeilly, A.S. and Illingworth, P.J. (1996b) Expression of tissue inhibitor of metalloproteinases-1 in the human corpus luteum after luteal rescue. J. Endocrinol., 148, 59-67.
20. Ellinwood, W.E., Norman, R.L. and Spies, H.G. (1984) Changing frequency of pulsatile LH and progesterone secretion during the luteal phase of the menstrual cycle of rhesus monkeys. Biol. Reprod., 31, 714-722.
21. Fisch, B., Margara, R.A., Winston, R.M.L. and Hillier, S.G. (1990) Cellular basis of luteal steroidogenesis in the human ovary. J. Endocrinol., 122, 303-311.
22. Fraser, H.M., Abbott, M., Laird, N.C. et al. (1986) Effects of an LHRH antagonist on the secretion of LH, FSH, prolactin and ovarian steroids at different stages of the luteal phase in the stumptailed (Macca arctoides). J. Endocrinol., 111, 83-89.
23. Hartung, S., Rust, W., Balvers, M. and Ivell, R. (1995) Molecular cloning and in vivo expression of the bovine steroidogenic acute regulatory protein. Biochem. Biophys. Res. Comm., 215, 646-653.
24. Hild-Petito, S. and Fazleabas, A.T. (1997) Expression of steroid receptors and steroidogenic enzymes in the baboon (Papio anubis) corpus luteum during the menstrual cycle and early pregnancy. J. Clin. Endocrinol. Metab., 82, 955-962.
25. Hutchison, J.S. and Zeleznik, A.J. (1984) The rhesus monkey corpus luteum is dependent on pituitary gonadotropin secretion throughout the luteal phase of the menstrual cycle. Endocrinology, 115, 1780-1786.
26. Hutchison, J.S., Nelson, P.B. and Zeleznik, A.J. (1986) Effects of different gonadotrophin pulse frequencies on corpus luteum function during the menstrual cycle of rhesus monkeys. Endocrinology, 119, 1964-1971.
27. Illingworth, P.J., Reddi, K., Smith, K. and Baird, D.T. (1990) Pharmacologic 'rescue' of the corpus luteum results in increased inhibin production. Clin. Endocrinol., 33, 323-332.
28. Juengel, J.L., Meberg, B.M., Turzillo, A.M. et al. (1995) Hormonal regulation of messenger ribonucleic acid encoding steroidogenic acute regulatory protein in ovine corpora lutea. Endocrinology, 136, 5423-5429.
29. King, S.R., Ronen-Fuhrmann, T., Timberg, R. et al. (1995) Steroid production after in vitro transcription, translation, and mitochondrial processing of protein products of complementary deoxyribonucleic acid for steroidogenic acute regulatory protein. Endocrinology, 136, 5165-5176.
30. Kiriakidou, M., McAllister, J.M., Sugawara, T. and Strauss, J.F. III (1996) Expression of steroidogenic acute regulatory protein (StAR) in the human ovary. J. Clin. Endocrinol. Metab., 81, 4122-4128.
31. Li, T.C., Rogers, A.W., Dockery, P. et al. (1988) A new method of histologic dating of human endometrium in the luteal phase. Fertil. Steril., 50, 52-60.
32. Lin, D., Sugawara, T., Strauss, J.F. III et al. (1995) Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis. Science, 267, 1828-1831.
33. Lobb, D.K., Soliman, S.R., Daya, S. and Younglai, E.V. (1998) Steroidogenesis in luteinized granulosa cell cultures varies with follicular priming regimen. Hum. Reprod., 13, 2064-2067.
34. McNeilly, A.S., Kenn, J., Swanston, I.A. et al. (1980) Changes in the binding of human chorionic gonadotrophin/luteinizing hormone, follicle-stimulating hormone and prolactin to human corpora lutea during the menstrual cycle and pregnancy. J. Endocrinol., 87, 315-325.
35. Nappi, C., Gargiulo, A.R. and Di Carlo, C. (1994) The human luteal paracrine system: current concepts. J. Endocrinol. Invest., 17, 825-836.
36. Nishimori, K., Dunkel, L., Hsueh, A.J.W. et al. (1995) Expression of luteinizing hormone and chorionic gonadotropin receptor messenger ribonucleic acid in human corpora lutea during menstrual cycle and pregnancy. J. Clin. Endocrinol. Metab., 80, 1444-1448.
37. Oonk, R.B., Krasnow, J.S., Beattie, W.G. and Richards, J.S. (1989) Cyclic AMP-dependent and independent regulation of cholesterol side chain cleavage cytochrome P-450 in rat ovarian granulosa cells and corpora lutea. J. Biol. Chem., 264, 21934-21942.
38. Ottander, U., Nakata, M., Bäckström, T. et al. (1997) Compartmentalization of human chorionic gonadotrophin sensitivity and luteinizing hormone receptor mRNA in different subtypes of the human corpus luteum. Hum. Reprod., 12, 1037-1042.
39. Ravindranath, N., Little-Ihrig, L.L. and Zeleznik, A.J. (1992a) Characterization of the levels of messenger ribonucleic acid that encode for luteinizing hormone receptor during the luteal phase of the primate menstrual cycle. J. Clin. Endocrinol. Metab., 74, 779-785.
40. Ravindranath, N., Little-Ihrig, L.L., Benyo, D.F. and Zeleznik, A.J. (1992b) Role of luteinizing hormone in the expression of cholesterol side-chain cleavage cytochrome P450 and 3β-hydroxysteroid dehydrogenase in the primate corpus luteum. Endocrinology, 131, 2065-2070.
41. Sanders, S.L. and Stouffer, R.L. (1997) Localization of steroidogenic enzymes in macaque luteal tissue during the menstrual cycle and simulated early pregnancy: immunohistochemical evidence supporting the two-cell model for estrogen production in the primate corpus luteum. Biol. Reprod., 56, 1077-1087.
42. Segaloff, D.L. and Ascoli, M. (1993) The lutropin/choriogonadotropin receptor... 4 years later. Endocrine Rev., 14, 324-347.
43. Simpson, E.R. and Boyd, G.S. (1967) The cholesterol side-chain cleavage system of the adrenal cortex. J. Biochem., 2, 275-285.
44. Stocco, D.M. and Clark, B.J. (1996) Regulation of the acute production of steroids in steroidogenic cells. Endocrine Rev., 17, 221-244.
45. Strauss, J.F. III and Miller, W.L. (1991) Molecular basis of ovarian steroid synthesis. In Hillier, S.G. (ed.), Ovarian Endocrinology. Blackwell Scientific Publications, Oxford, UK, pp. 25-72.
46. Sugawara, T., Holt, J.A., Driscoll, D. et al. (1995) Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13. Proc. Natl. Acad. Sci. USA, 92, 4778-4782.
47. Suzuki, T., Sasano, H., Tamura, M. et al. (1993) Temporal and spacial localization of steroidogenic enzymes in premenopausal human ovaries: in situ hybridization and immunohistochemical study. Mol. Cell. Endocrinol., 97, 135-143.
48. scc (20,22-desmolase) and P450c17 (17α-hydroxylase/17,20-lyase) in cultured human granulosa cells. J. Clin. Endocrinol. Metab., 63, 202-207.
49. Zeleznik, A.J. and Hillier, S.G. (1996) The ovary: endocrine function. In Hillier, S.G., Kitchener, H.C. and Neilson, J.P. (eds), Scientific Essentials of Reproductive Medicine. W.B. Saunders, London, UK, pp. 133-146.