Sequence polymorphisms between latent membrane proteins LMP1 and LMP2A do not correlate in EBV-associated reactive and malignant lympho- proliferations

International Journal of Cancer

Volumn 81, Issue 3, 1999, Pages 371-375

  Berger, Christoph ^a,c   Rothenberger, Sylvia ^b   Bachmann, Edith ^b   McQuain, Cathy ^a   Nadal, David ^c   Knecht, Hans ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LATENT MEMBRANE PROTEIN 1;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHILD; CYTOTOXIC T LYMPHOCYTE; DNA POLYMORPHISM; DNA SEQUENCE; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; LYMPHOMA; MAJOR CLINICAL STUDY; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0032913903     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990505)81:3<371::AID-IJC10>3.0.CO;2-D     Document Type: Article

References (22)

1. AZUMA, M., CAYABYAB, M, BUCK, D., PHILLIPS, J.H. and LANIER, L.L., CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. J. exp. Med., 175, 353-360 (1992).
2. BERGER, C., BROUSSET, P., MCQUAIN, C. and KNECHT, H., Deletion variants within the NF-κB activation domain of the LMP1 oncogene in acquired immunodeficiency syndrome related large cell lymphomas, prelymphomas and atypical lympho-proliferations. Leukemia Lymphoma, 26, 239-250 (1997).
3. BERGER, C., VAN BAARLE, D., KERSTEN, M.J., KLEIN, M.R., AL-HOMSI, A.S., DUNN, B., MCQUAIN, C., VAN OERS, R. and KNECHT, H., Carboxy-terminal variants of EBV encoded latent membrane protein 1 during long term HIV-infection: markers for individual strain identification. J. infect. Dis. 179, 240-244 (1999).
4. BRODEUR, S.R., CHENG, G., BALTIMORE, D. and THORLEY-LAWSON, D.A., Localization of the major NF-κB-activating site and the sole TRAF3 binding site of LMP1 defines two distinct signaling motifs. J. biol. Chem., 272, 19777-19784 (1997).
5. DEVERGNE, O., HATZIVASSILIOU, E., IZUMI, K.M., KAYE, K.M., KLEUNEN, M.F., KIEFF, E. and MOSIALOS, G., Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation. Mol. cell. Biol., 16, 7098-7108 (1996).
6. ELIOPOULOS, A.G. and RICKINSON, A.B., Epstein-Barr virus: LMP1 masquerades as an active receptor. Curr. Biol., 8, R196-R198 (1998).
7. HU, L.F., ZABAROVSKY, E.R., CHEN, F., CAO, S.F., ERNBERG, I., KLEIN, G. and WINBERG, G., Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma. J. gen. Virol., 72, 2399-2409 (1991).
8. KIESER, A., KILGER, E., GIRES, O., UEFFING, M., KOLCH, W. and HAMMERSCHMIDT, W., Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade. EMBO J., 16, 6478-6485 (1997).
9. KNECHT, H., BACHMANN, E., BROUSSET, P., SANDVEJ, K., NADAL, D., BACHMANN, F., ODERMATT, B.F., DELSOL, G. and PALLESEN, G., Deletions within the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma. Blood, 82, 2937-2942 (1993).
10. KNECHT, H., BERGER, C., AL-HOMSI, A.S., MCQUAIN, C. and BROUSSET, P., Epstein-Barr virus oncogenesis. Crit. Rev. Oncol. Hematol., 26, 117-135 (1997).
11. LEE, S.P., THOMAS, W.A., MURRAY, R.J., KHANIM, F., KAUR, S., YOUNG, L.S., ROWE, M., KURILLA, M. and RICKINSON, A.B., HLA-A2.1-restricted cytotoxic T cells recognizing a range of Epstein-Barr virus isolates through a defined epitope in latent membrane LMP2. J. Virol., 67, 7428-7435 (1993).
12. LONGNECKER, R. and MILLER, C., Regulation of Epstein-Barr virus latency by latent membrane protein 2. Trends Microbiol., 4, 38-42 (1996).
13. MILLER, C.L., BURKHARDT, A.L., LEE, J.H., STEALEY, B., LONGNECKER, R., BOLEN, J.B. KIEFF, E., Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases. Immunity, 2, 155-166 (1995).
14. MILLER, W.E., CHESHIRE, J.L. and RAAB-TRAUB, N., Interaction of tumor necrosis factor receptor-associated factor signaling proteins with the latent membrane protein 1 PXQXT motif is essential for induction of epidermal growth factor receptor expression. Mol. cell. Biol., 18, 2835-2844 (1998).
15. RICKINSON, A.B. and KIEFF, E., Epstein Barr virus. In: B.N. Fields, D.M. Knipe, P.M. Howley, et al. (eds.). Fields virology (3rd ed.), pp. 2397-2446, Lipincott-Raven, Philadelphia (1996).
16. ROTHENBERGER, S., BACHMANN, E., BERGER, C., MCQUAIN, C., ODERMATT, B.F. and KNECHT, H., Natural 30 bp and 69 bp deletion variants of the LMP1 oncogene do stimulate NF-κB mediated transcription. Oncogene, 14, 2123-2126 (1997).
17. SANDBERG, M., HAMMERSCHMIDT, W. and SUGDEN, B., Characterization of LMP-1's association with TRAFI. TRAF2. and TRAF3. J. Virol., 71, 4649-4656 (1997).
18. SHEN, H.M., PETERS, A., BARON, B., ZHU, X. and STORB, U., Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes. Science, 280, 1750-1752 (1998).
19. SONGYANG, Z. and 16 OTHERS, SH2 domains recognize specific phosphopeptide sequences. Cell, 72, 767-778 (1993).
20. WALLING, D.M., CLARK, N.M., MARKOVITZ, D.M., FRANK, T.S., BRAUN, D.K., EISENBERG, E., KRUTCHKOFF, D.J., FELIX, D.H. and RAAB-TRAUB, N., Epstein-Barr virus confection and recombination in non-human immunodeficiency virus-associated oral hairy leukoplakia. J. Infect. Dis., 171, 1122-1130 (1995).
21. YAO, Q.Y., RICKINSON, A.B. and EPSTEIN, M.A., A re-examination of the Epstein-Barr virus carrier state in healthy seropositive individuals. Int. J. Cancer, 35, 35-42 (1985).
22. YAO, Q.Y., TIERNEY, R.J., CROOM-CARTER, D., COOPER, G.M., ELLIS, C.J., ROWE, M. and RICKINSON, A.B., Isolation of intertypic recombinants of Epstein-Barr virus from T-cell-immunocompromised individuals. J. Virol., 70, 4895-4903 (1996).