Antioxidant-angioprotective actions of calcium dobesilate in diabetic rats

International Journal of Angiology

Volumn 8, Issue SUPPL. 1, 1999, Pages

  Hannaert, Patrick ^a   Brunet, John ^a   Farine, Jean Claude ^b   Garay, Ricardo P ^a  

^a INSERM   (France)

^b Vifor (International) Inc   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOBESILATE CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; CAPILLARY PERMEABILITY; CONFERENCE PAPER; DIABETIC ANGIOPATHY; DOSE RESPONSE; DRUG EFFECT; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 0032913841     PISSN: 10611711     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf01619841     Document Type: Conference Paper

References (21)

1. Leite E, Mota M, J. Faria de Abreu J, J. Cunha-Vaz J (1990) Effect of calcium dobesilate on the blood-retinal barrier in early diabetic retinopathy. Int Ophtalm 14:81-88.
2. Vojnikovic B (1991) Doxium® (calcium dobesilate) reduces blood hyperviscosity and intraocular pressure in patients with diabetic retinopathy and glaucoma. Ophtalm Res 23:12-20.
3. Widmer L, Biland L, Barras JP (1990) Doxium® 500 dans le traitement de l'insuffisance veineuse chronique: étude multicentre en dobule aveugle conter placebo. Int Angiol 9:105-110.
4. Beyer J, Meissner HJ, Cordes U (1980) Calcium dobesilate reduces microvascular permeability to plasma proteins in diabetes mellitus. Med Wochenschr 105:1604-1608.
5. Bijsterveld J, Janssen PT (1981) The effect of calcium dobesilate on albumin leakage of the conjunctival vessels. Curr Eye Res 1:425-430.
6. Baynes JW (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-77.
7. Doly M, Droy-Lefaix MT (1992) Lipid peroxidation in the pathology of the retina. In: Free radicals in the brain aging. Neurological and mental disorders, Packer L, Prilipko L, Christen Y (eds) (Berlin-Heidelberg) Springer-Verlag, pp 123-139.
8. Halliwell B (1993) The role of oxygen radicals in human disease with particular reference to the vascular system. Haemostasis 23:118-126.
9. Brunet J, Farine JC, Garay RP, Hannaert P (1998) In vitro antioxidant properties of calcium dobesilate. Fundam Clin Pharmacol 12:205-212.
10. Brunet J, Farine JC, Garay RP, Hannaert P (1998) Angioprotective action of calcium dobesilate against reactive oxygen species-induced capillary permeability in the rat. Eur J Pharmacol 358:213-220.
11. Tomlison KC, Gardiner SM, Hebden RA, Kenneth T (1992) Functional consequences of streptozotocin-induced Diabetes Mellitus, with particular reference to the cardiovascular system. Pharmacol Rev 44: 103-150.
12. Tucker BJ (1990) Early onset of increased transcapillary albumin escape in awake diabetic rats. Diabetes 89:918-928.
13. Parving H, Nielsen S, Bang L, Smidt U, Svendsen T, Chen J, Gall M, Rossing P (1996) Macro-angiopathy and endothelial dysfunction in NIDDM patients with and without diabetic nephropathy. Diabetologia 39:1590-1597.
14. Yamaji T, Fukuhara T, Kinoshita M (1993) Increased capillary permeability in diabetic rat myocardium. Circ Res 72:947-957.
15. Valensi P, Attali J, Behar A, Attalah M, Sebaoun J (1991) Increased capillary permeability to albumin and diabetic neuropathy. Diabetes Res Clin Pract 11:41-46.
16. Valensi P, Attali J, Behar A, Sebaoun J (1987) Isotopic test of capillary permeability to albumin in diabetic patients: effects of hypertension, microangiopathy, and duration of diabetes. Metabolism 36:834-839.
17. Viberti G (1983) Increased permeability in diabetes mellitus and its relationship to microvascular angiopathy. Am J Med 75:81-84.
18. Plante G, Chakir M, Ettaouil K, Lehoux S, Sirois P (1995) Consequences of alteration in capillary permeability. Can J Physiol Pharmacol 74:824-833.
19. Williamson JR, Puoliese G, Tilton R, Chang K, Kilo C (1990) In vivo vascular permeability changes in diabetes: experimental animals. Front Diabetes 9:48-90.
20. Kernell A, Arnqvist H (1983) Effect of insulin treatment on the blood-retinal barrier in rats with streptozotocin-induced diabetes. Arch Opthalmol 101:968-970.
21. Rota R, Pallotta M, Garay R, Giraud F, Courseau C, Hannaert P (1994) Activité pro-oedémateuse de la lacidipine, de la nitrendipine et de la nifédipine chez les rats spontanément hypertendu. Arch Mal Cœur 87:975-977.