Adenoviral-mediated gene transfer of a constitutively active form of the retinoblastoma gene product attenuates neointimal thickening in experimental vein grafts

Journal of Vascular Surgery

Volumn 29, Issue 5, 1999, Pages 874-883

  Schwartz, L B ^a   Moawad, J ^a   Svensson, E C ^a   Tufts, R L ^a   Meyerson, S L ^a   Baunoch, D ^a   Leiden, J M ^a   Matsumura, J ^a   Hoch, J ^a   Gloviczki, P ^a   O'Hara, P ^a   Greisler, H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; RETINOBLASTOMA PROTEIN;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; INTIMA; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; TUMOR SUPPRESSOR GENE; VEIN GRAFT;

EID: 0032911815     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(99)70215-6     Document Type: Article

References (42)

1. LB Schwartz MK O'Donohoe CM Purut EM Mikat P-O Hagen RL McCann Myointimal thickening in experimental vein grafts is dependent on wall tension J Vasc Surg 15 1992 176 186
2. LB Schwartz JC Pence BJ Kerns JD Iglehart RL McCann P Hagen Kinetics of experimental vein graft cell division and function Surg Forum 27 1991 363 365
3. WC Quist CC Haudenschild FW LoGerfo Qualitative microscopy of implanted vein grafts. Effects of graft integrity on morphologic fate J Thorac Cardiovasc Surg 103 1992 671 677
4. WC Quist FW LoGerfo Prevention of smooth muscle cell phenotypic modulation in vein grafts: a histomorphometric study J Vasc Surg 16 1992 225 231
5. PA Hamel RM Gill BL Phillips BL Gallie Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene Mol Cell Biol 12 1992 3431 3438
6. SK Tripathy E Goldwasser MM Lu E Barr JM Leiden Stable delivery of physiologic levels of recombinant erythropoietin to the system circulation by intramuscular injection of replication-defective adenovirus Proc Natl Acad Sci U S A 91 1994 11557 11561
7. DW Kim T Harada I Saito T Miyamura An efficient expression vector for stable expression in human liver cells Gene 134 1993 307 308
8. WM Struass Preparation of genomic DNA from mammalian tissue FM Ausubel R Brent RE Kingston Current protocols in molecular biology 1989 John Wiley & Sons New York 2.2.1 223
9. MERCATOR Study Group Does the new angiotensin-converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Circulation 86 1992 100 110
10. SG Ellis GS Roubin J Wilentz JS Douglas SB King Effect of 18- and 24-hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty Am Heart J 117 1989 777 782
11. KG Lehmann RJ Doria JM Feuer PX Hall DT Hoang Paradoxical increase in restenosis rate with chronic heparin use: final results of a randomized trial [abstract] J Am Coll Cardiol 17 1991 181A
12. Lovastatin Restenosis Trial Study Group Lovastatin restenosis trial: results in patients with cholesterol over 200 mg/dl [abstract] J Am Coll Cardiol 23 1994 407A
13. SE Epstein E Speir E Unger RJ Guzman T Finkel The basis of molecular strategies for treating coronary restenosis after angioplasty J Am Coll Cardiol 23 1994 1278 1288
14. GH Gibbons VJ Dzau Molecular therapies for vascular diseases Science 272 1996 689 693
15. MR Bennett SM Schwartz Antisense therapy for angioplasty restenosis: some critical considerations Circulation 92 1995 1981 1993
16. S Chen JM Wilson DWM Muller Adenovirus-mediated gene transfer of soluble vascular cell adhesion molecule to porcine interposition vein grafts Circulation 89 1994 1922 1928
17. JM Kupfer XM Ruan G Liu J Matloff J Forrester A Chaux High-efficiency gene transfer to autologous rabbit jugular vein grafts using adenovirus-transferrin/polylysine-DNA complexes Hum Gene Ther 5 1994 1437 1443
18. MA Golden Modification of vein graft adaptation using adenoviral vectors J Vasc Surg 24 1996 161 163
19. J Moawad LB Schwartz BL Gewertz MW Chang JM Leiden Efficiency of adenoviral-mediated gene transfer in experimental vein grafts Proceedings of the Twenty-first Annual Meeting of the Midwestern Vascular Surgical Society 1997 Sep 12–13 Chicago, Ill
20. PHA Quax MLM Lamfers J Grimbergen J Teeling G van Nieuw Amerongen VMW van Hinsbergh Effects of adenoviral infection on umbilical vein endothelial and smooth muscle cells [abstract] J Vasc Res 33 suppl 1 1996 320
21. KM Channon GJ Fulton JL Gray BH Annex GA Shetty MA Blazing Efficient adenoviral gene transfer to early venous bypass grafts: comparison with native vessels Cardiovasc Res 35 1997 505 513
22. MJ Mann GH Gibbons RS Kernoff FP Diet PS Tsao JP Cooke Genetic engineering of vein grafts resistant to atherosclerosis Proc Natl Acad Sci U S A 92 1995 4502 4506
23. GJ Fulton MG Davies RJ Lefkowitz E Svendsen WJ Koch P-O Hagen Transfection with b ARKCT reduces intimal hyperplasia in experimental vein grafts Surg Forum 47 1996 341 345
24. PHA Quax ML Lamfers JG Grimbergen JH Verheijen V van Hinsberg Inhibition of neointima formation in cultured human saphenous vein segments by an adenovirus expressing an urokinase receptor binding plasmin inhibitor [abstract] Circulation 96 suppl I 1997 I-669
25. T Matsumoto K Komori Y Yonemitsu R Morishita K Sueishi Y Kaneda Hemagglutinating virus of Japan-liposome-mediated gene transfer of endothelial cell nitric oxide synthase inhibits intimal hyperplasia of canine vein grafts under conditions of poor runoff J Vasc Surg 27 1998 135 144
26. R Morishita GH Gibbons M Horiuchi KE Ellison M Nakama L Zhang A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo Proc Natl Acad Sci U S A 92 1995 5855 5859
27. MJ Mann AD Whittemore MC Donaldson MA Belkin J Orav J Polak Preliminary clinical experience with genetic engineering of human vein grafts: evidence for target gene inhibition [abstract] Circulation 96 suppl I 1997 I-4
28. RE Hollingsworth Jr CE Hensey WH Lee Retinoblastoma protein and the cell cycle Curr Opin Genet Dev 3 1993 55 62
29. JA DeCaprio Y Furukawa F Ajchenbaum JD Griffin DM Livingston The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression Proc Natl Acad Sci U S A 89 1992 1795 1798
30. BA Karpinski GD Morle J Huggenvik MD Uhler JM Leiden Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element Proc Natl Acad Sci U S A 89 1992 4820 4824
31. CY Wang B Petryniak CB Thompson WG Kaelin JM Leiden Regulation of the Ets-related transcription factor Elf-1 by binding to the retinoblastoma protein Science 260 1993 1330 1335
32. LB Schwartz CM Purut MK O'Donohoe PK Smith P-O Hagen RL McCann Quantitation of vascular outflow by measurement of impedance J Vasc Surg 14 1991 353 363
33. LR Bandara NB La Thangue Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor Nature 351 1991 494 497
34. K Mihara XR Cao A Yen S Chandler B Driscoll AL Murphree Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product Science 246 1989 1300 1303
35. MW Chang E Barr J Seltzer YQ Jiang GJ Nabel EG Nabel Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product Science 267 1995 518 522
36. RC Smith KN Wills D Antelman H Perlman LN Truong K Krasinski Adenoviral constructs encoding phosphorylation-competent full-length and truncated forms of the human retinoblastoma protein inhibit myoctye proliferation and neointima formation Circulation 96 1997 1899 1905
37. KD Newman PF Dunn JW Owens AH Schulick R Virmani G Sukhova Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia J Clin Invest 96 1995 2955 2965
38. N Muzyczka Use of adeno-associated virus as a general transduction vector for mammalian cells Curr Top Microbiol Immunol 158 1992 97 129
39. F Rolling Z Nong S Pisvin D Collen Adeno-associated virus-mediated gene transfer into rat carotid arteries Gene Ther 4 1997 757 761
40. CM Lynch PS Hara JC Leonard JK Williams RH Dean RL Geary Adeno-associated virus vectors for vascular gene delivery Circ Res 80 1997 497 505
41. RM Kotin Prospects for the use of adeno-associated virus as a vector for human gene therapy Human Gene Ther 5 1994 793 801
42. EC Svensson DJ Marshall K Woodard H Lin F Jiang L Chu Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors Circulation 99 1999 201 205