Mechanisms involved in the vasorelaxant effect of (-)-stepholidine in rat mesenteric small arteries

European Journal of Pharmacology

Volumn 365, Issue 2-3, 1999, Pages 193-204

  Lei, Shi ^a   Orensanz, Luis M ^b   J Mulvany, Michael ^a   Simonsen, Ulf ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

( ) Stepholidine; Adrenoceptor; Dopamine receptor; Electrical field stimulation; Mesenteric small artery; Rat

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; DOPAMINE RECEPTOR BLOCKING AGENT; GLIBENCLAMIDE; NORADRENALIN; POTASSIUM CHLORIDE; STEPHOLIDINE; TETRYLAMMONIUM;

ANIMAL TISSUE; ARTERY; ARTICLE; CONTROLLED STUDY; ENANTIOMER; ENDOTHELIUM; IN VITRO STUDY; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

ANIMALS; BERBERINE; BERBERINE ALKALOIDS; CALCIUM CHANNELS; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; MALE; MESENTERIC ARTERIES; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; POTASSIUM CHANNELS; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC; RECEPTORS, MUSCARINIC; SEROTONIN;

EID: 0032908597     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00880-2     Document Type: Article

References (48)

1. 3H] Prazosin binding to central nervous system regions of male and female rats Neurosci. Lett. 49:1984;193-197.
2. Angus J.A., Broughton A., Mulvany M.J. Role of α-adrenoceptors in constrictor responses of rat, guinea pig and rabbit small arteries to neural activation. J. Physiol. 403:1988;495-510.
3. Arunlakshana O., Schild H.O. Some quantitative uses of drug antagonists. Br. J. Pharmacol. Chemother. 14:1959;48-58.
4. + channels in arterial and intestinal smooth muscle membranes. Pflug. Arch. 403:1985;120-127.
5. Bradford M.A. Rapid and sensitive method for the quantititation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
6. Brochmann-Hansen E., Richter W.J. Opium alkaloids XV: isolation of stepholidine. J. Pharm. Sci. 64:1975;1040-1041.
7. Brodde O.-E., Meyer F.-J., Schemuth W., Freist hler J. Demonstration of specific vascular dopamine receptors mediating vasodilation on the isolated rabbit mesenteric artery. Naunyn-Schmiedeberg's Arch. Pharmacol. 316:1981;24-30.
8. Cava M.P., Nomura K., Talapatra S.K., Mitchell M.J., Schlessinger R.H., Buck K.T., Beal J.L., Douglas B., Raffauf R.F., Weisbach J.A. The alkaloids of Stephania glabra. A direct chemical correlation of the absolute configuration of some benzyltetrahydroisoquinoline, proaporphine, and aporphine alkaloids. A new protoberberine alkaloid. J. Org. Chem. 33:1968;2785-2789.
9. Chen H., Fetscher C., Schafers R.F., Wambach G., Philipp T., Michel M.C. Effects of noradrenaline and neuropeptide Y on rat mesenteric microvessel contraction. Naunyn-Schmiedeberg's Arch. Pharmacol. 353:1996;314-323.
10. Cheng Y., Prusoff W.H. Relationship between the inhibition constant (K1) and the concentration of inhibitor. Biochem. Pharmacol. 22:1973;3099-3108.
11. Chiou W.-F., Liao J.-F., Shum A.Y.-C., Chen C.-F. Mechanisms of vasorelaxant effect of dehydroevodiamine: a bioactive isoquinolinocarboline alkaloid of plant origin. J. Cardiovasc. Pharmacol. 27:1996;845-853.
12. Chiou W.-F., Shum A.Y.-C., Liao J.-F., Chen C.-F. Studies of the cellular mechanisms underlying the vasorelaxant effects of rutaecarpine, a bioactive component extracted from an herbal drug. J. Cardiovasc. Pharmacol. 29:1997;490-498.
13. Christensen K.L., Mulvany M.J. Mesenteric arcade arteries contribute substantially to vascular resistance in conscious rats. J. Vasc. Res. 30:1993;73-79.
14. Chuliá S., Ivorra M.D., Lugnier C., Vila E., Noguera M.A., D'Ocon P. Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines. Br. J. Pharmacol. 113:1994;1377-1385.
15. Chuliá S., Ivorra M.D., Martinez S., Elorriaga M., Valiente M., Noguera M.A., Lugnier C., Advenier C., D'Ocon P. Relationships between structure and vascular activity in a series of benzylisoquinolines. Br. J. Pharmacol. 122:1997;409-416.
16. 1-receptor blockade and angiotensin converting enzyme inhibition on the renal actions of fenoldopam in anaesthetized dog. J. Hypertens. 9:1991;1143-1150.
17. Deng X.F., Chemtob S., Varma D.R. Characterization of alpha-1D-adrenoceptor subtype in rat myocardium, rat and other tissues. Br. J. Pharmacol. 119:1996;269-276.
18. Donoso M.V., Steiner M., Huidobro-Toro J.P. BIBP 3226, suramin, and prazosin identify neuropeptide Y, adenosine 5′-triphosphate and noradrenaline as sympathetic cotransmitters in the rat arterial mesenteric bed. J. Pharmacol. Exp. Ther. 282:1997;691-698.
19. Hahn R.A., MacDonald B.R. Primate cardiovascular responses by dopamine receptors: effects of N,N-di-n-propyldopamine and LY171555. J. Pharmacol. Exp. Ther. 229:1984;132-138.
20. Hall A.S., Bryson S.E., Vaughan P.F.T., Ball S.G., Balmforth A.J. Pharmacological characterization of the dopamine receptor coupled to cyclic AMP formation expressed by rat mesenteric artery vascular smooth muscle cells in culture. Br. J. Pharmacol. 110:1993;681-686.
21. 1-adrenoceptors in rat blood vessels. Eur. J. Pharmacol. 190:1990;97-104.
22. Heesen B.-J., De Mey J.G.R. Effects of cyclic AMP affecting agents on contractile reactivity of isolated mesenteric and renal resistance arteries of the rat. Br. J. Pharmacol. 101:1990;859-864.
23. 1) receptor agonists on human isolated subcutaneous and omental small arteries. Br. J. Pharmacol. 97:1989;950-956.
24. 1 antagonist. Eur. J. Pharmacol. 91:1983;153-158.
25. 1-receptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 339:1989;483-485.
26. 1A-adrenoceptors in rat mesenteric small arteries. Eur. J. Pharmacol. 336:1997;29-35.
27. 1-adrenoceptor and benzothiazepine binding site at the calcium channel. Br. J. Pharmacol. 106:1992;387-394.
28. 2+ channels. Eur. J. Pharmacol. 231:1993;165-174.
29. Jin G.-Z. (-)-Tetrahydropalmitine and its analogues as new dopamine receptor antagonists. Trends Pharmacol. Sci. 8:1987;81-82.
30. Jin G.-Z., Huang K.-X., Sun B.-C. Dual actions of (-)-stepholidine on dopamine receptor subtypes after substantia nigra lesion. Neurochem. Int. 20:1992;175S-178S.
31. Lokhandwala, M.F., DeFeao, M.L., 1988. Neuronal dopamine receptors. In: Bell, C., McGrath, B. (Eds.), Peripheral Actions of Dopamine. Macmillan, London, pp. 24-41.
32. Luchsinger A., Grilli M., Forte P., Morales E., Velasco M. Metoclopramide blocks bromocriptine induced antihypertensive effect in hypertensive patients. Int. J. Clin. Pharmacol. Ther. 33:1995;509-512.
33. 1A-adrenoceptor subtype. Br. J. Pharmacol. 119:1996;1563-1568.
34. Mulvany M.J., Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive rats. Circ. Res. 41:1977;19-26.
35. Mulvany M.J., Warshaw D.M. The active tension length curve of vascular smooth muscle related to its cellular components. J. Gen. Physiol. 74:1979;85-104.
36. 2-receptors in jejunal arteries of rabbits. J. Cardiovasc. Res. 18:1991;468-471.
37. Nielsen H., Pilegaard H.K., Hasenkam J.M., Mortensen F.V., Mulvany M.J. Heterogeneity of postjunctional α-adrenoceptors in isolated mesenteric resistance arteries from rats, pigs, and humans. J. Cardiovasc. Pharmacol. 18:1991;4-10.
38. Plane F., Garland C.J. Influence of contractile agonists on the mechanism of endothelium-dependent relaxation in rat isolated mesenteric artery. Br. J. Pharmacol. 119:1996;191-193.
39. + channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide. J. Pharmacol. Exp. Ther. 250:1989;261-271.
40. Schott C., Tetsi L., Heitz C., Stambach J.-F., Jung L., Stoclet J.C. Stereoselective blockade of α-adrenoceptors by berbine derivatives. Arzneim.-Forsch. Drug Res. 11:1988;1567-1571.
41. Seeman P., Van Tol H.H. Dopamine receptor pharmacology. Trends Pharmacol. Sci. 15:1994;264-270.
42. Singewald N., Philippu A. Involvement of biogenic amines and amino acids in the central regulation of cardiovascular homeostasis. Trends Pharmacol. Sci. 17:1994;356-363.
43. Sjöblom-Widfeldt N. Neuromuscular transmission in blood vessels: phasic and tonic components. Acta Physiol. Scand. 138(Suppl. 587):1990;1-52.
44. Soares da Silva, P., 1988. Dopamine storage in sympathetic nerves. In: Bell, C., McGrath, B. (Eds.), Peripheral Actions of Dopamine. Macmillan, London, pp. 24-41.
45. Sun B.-C., Jin G.-Z. Characteristics of (-)-stepholidine on the firing activity of substantia nigral dopamine neurons after repeated reserpine treatment. Biol. Signals. 1:1992;331-338.
46. 1B-adrenoceptor subtype. Br. J. Pharmacol. 114:1995;745-750.
47. Van der Graaf P.H., Saxena P.R., Shankley N.P., Black J.W. Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium independent relaxation of rat isolated small mesenteric arteries. Br. J. Pharmacol. 116:1995;3237-3242.
48. Yang S., Miao Y.-S., Han Q., Jiang M.-H., Jin G.-Z. Effects of (-)-stepholidine and tetrahydroberberine on high potassium evoked contraction and calcium influx in rat artery. Acta Pharmacol. Sin. 14:1993;235-237.