Novel esters and amides of nonsteroidal antiinflammatory carboxylic acids as antioxidants and antiproliferative agents

Journal of Medicinal Chemistry

Volumn 42, Issue 2, 1999, Pages 267-276

  Hellberg, Mark R ^a   Namil, Abdelmoula ^a   Delgado, Pete ^a   David, Karen C ^a   Kessler, Timothy L ^a   Graff, Gustav ^a   Haggard, Karen S ^a   Nixon, Jon C ^a  

^a ALCON RESEARCH LTD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 METHOXY ALPHA METHYLNAPHTHALENEACETIC ACID (3,4 DIHYDRO 6 HYDROXY 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 2 YL)METHYLAMIDE; 6 METHOXY ALPHA METHYLNAPHTHALENEACETIC ACID 2 (3,4 DIHYDRO 6 HYDROXY 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 2 YL)ETHYL ESTER; NAPROXEN DERIVATIVE; TROLOX C; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; DNA SYNTHESIS INHIBITION; DRUG CONFORMATION; DRUG POTENCY; DRUG SYNTHESIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; STRUCTURE ACTIVITY RELATION; VASCULAR ENDOTHELIUM;

AMIDES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; CARBOXYLIC ACIDS; CATTLE; CELL DIVISION; CELLS, CULTURED; CHILD, PRESCHOOL; DNA; ENDOTHELIUM, VASCULAR; ESTERS; FEMALE; HUMANS; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE;

EID: 0032908552     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980430o     Document Type: Article

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