In vivo skin penetration enhancement of acyclovir by theoretical design of prodrug-enhancer combination

International Journal of Pharmaceutics

Volumn 145, Issue 1-2, 1996, Pages 103-113

  Bando, Hiroto ^a   Sahashi, Mikiko ^a   Mohri, Saya ^a   Yamashita, Fumiyoshi ^a   Takakura, Yoshinobu ^a   Hashida, Mitsuru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

1 Geranylazacycloheptan 2 one; Acyclovir; Acyclovir prodrugs; In vivo percutaneous absorption; Penetration enhancement; Prodrug enhancer combination

Indexed keywords

1 GERANYLAZACYCLOHEPTAN 2 ONE; ACICLOVIR; ACICLOVIR DERIVATIVE; ACICLOVIR ISOVALERATE; ACICLOVIR PIVALATE; ACICLOVIR VALERATE; PENETRATION ENHANCING AGENT; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG EXCRETION; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME ACTIVITY; HYDROLYSIS; IN VITRO STUDY; INFORMATION PROCESSING; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION; SKIN ABSORPTION; SKIN PENETRATION; THIN LAYER CHROMATOGRAPHY; TOPICAL DRUG ADMINISTRATION;

EID: 0030573077     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(96)04751-5     Document Type: Article

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